» Saw palmetto has the highest amount of free form fatty acids of any natural
» substance. Saw Palmetto reduced DHT levels in the prostate by 32 percent in
» this study:
» http://www.ncbi.nlm.nih.gov/entrez/eutils/escan.fcgi?db=PubMed&uid=11337315&dopt=Citation&field=Title&DateField=MeshDate
»
» Here is the money sentence: “In the randomized trial, tissue DHT levels
» were reduced by 32% from 6.49 to 4.40 ng/g in the SPHB group (P <0.005),
» with no significant change in the placebo group”
»
»
»
»
» my opinion----saw palmetto would seemingly be helpful on paper, but not as
» much as finasteride. But we wont know unless there is a big trial and that
» ain’t gonna happen, so I suppose folks just have to make decisions based
» on current information.
»
»
»
»
» More on why Saw Palmetto “should” help DHT levels,…
»
» Assay Title: Determination of fatty acids in Serenoa repens (Saw Palmetto
» or sabel) by gas chromatography.
»
» Scope: This assay can be used to determine fatty acid distribution in Saw
» Palmetto fruit, oil extract, and blended powders. Determination is
» performed using gas chromatography, after transesterification of the
» triglycerides, followed by conversion into the methyl ester.
»
» Safety Precautions: Consult the Material Safety Data Sheet (MSDS) for any
» chemical used that is unfamiliar. All chemicals should be considered
» hazardous - avoid direct physical contact. For more safety information,
» see http://hazard.com/msds/.
»
» Background: Saw palmetto fruit contains several principles thought to have
» physiological activity, including fatty acids such as caproic, capric,
» lauric, myristic, oleic, palmitic, stearic, and 1 to 2% essential oils.
» Furthermore, it contains sterols and high molecular weight
» polysaccharides. Purified ethanolic or CO2 extracts of saw palmetto
» usually contain 70 to 80% free fatty acids. The fatty acids present are in
» several forms - free fatty acids, fatty acid esters of the fatty alcohols,
» and fatty acid esters of the phytosterols. This oil is commonly blended
» with excipients to form a dry powder at 30% free fatty acids
» concentration.
»
» Standards: Note: This is not an all-inclusive listing of sources for
» reference standards. World wide there are many reputable suppliers of
» botanical reference standards whose product may be used. However quality
» control protocol and/or government regulation may mandate further
» qualification of the materials for proper identity and purity.
»
» Apparatus
»
» FAME Carbon Chain Indofine Cat. No. Nu-Chek Prep Cat. No. Sigma Cat. No.
» Hexanoic (Caproic) C6:0 02-3324S N-6-M C5049
» Octanoic (Caprylic) C8:0 02-2853S N-8-M C3375
» Nonanoic (Pelargonic) C9:0 02-2834 N-9-M N5627
» Decanoic (Capric) C10:0 02-3321S N-10-M C2125
» Dodecanoic (Lauric) C12:0 02-3114 N-12-M L7272
» Tetradecanoic (Myristic) C14:0 02-3141 N-14-M M3378
» Hexadecanoic (Palmitic) C16:0 02-3177 N-16-M P5177
» Heptadecanoic (Margaric) C17:0 02-3467 N-17-M H4515
» Octadecanoic (Stearic) C18:0 02-3195 N-18-M S5376
» 9-Octadecenoic (Oleic) C18:1 02-2762S N-46-M O4754
» 9,12- Octadecadienoic (Linoleic) C18:2 02-3344S N-59-M L1876
» 9,12,15- Octadecatrienoic (Linolenic)
»
»
» Of these, the myrsitic, linolenic, palmitic, and lauric have been shown if
» memeory serves to inhibit alpha five reductase at varrying concentrations.
»
»
» Sterols probably just block androgen receptors more than inhibit alpha
» five reductase enzymes. Especially beta sitosterol.
»
»
»
»
» An old study posted by hairsite done in Italy showed that Saw Palmetto
» reduced sebum, improved hair growth when given to men and a saw palmetto
» topical also helped the results further.
Saw Palmetto is one of the weakest DHT blockers out there, but some guys myself included respond extremely well to it,
Beta sis is 3000 times more powerful than Saw Palmetto, so I added that
pygeum and nettles will strenthen considerably , a natural dht blocker regimen, I feel they all work through different pathways since the more dht blockers I added the better my hair does
dont listen to the Natural, he has no clue of what he is talking about