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TRC results


#1

We we heard today was astounding news.

“All patients have now been treated in the Phase II trial of ICX-TRC, our hair regeneration product, and the results so far are promising.”

This means that phase 2 is close to completion since everyone has been treated. Remember that today’s report was upto 31st dec 2007. We are 12 weeks past that stage now.

"These data are consistent with the earlier data reported last September and the hypothesis that new hair production is improved by pre-stimulation of the scalp, leading to an interaction between the injected cells and the resident hair producing cells."

They tried a few variations but I think they’ve found the winning formula ie “pre - stimulation”

“We made considerable progress in 2007 in all of our programmes, generating clinical data across the product portfolio in a greatly expanded patient base. We are seeing very encouraging efficacy which gives us great confidence in the application of our technology and our commercial prospects.”

Their products are very close the market.

“As a company we have achieved much in a short time and with relatively modest cash resources.”

The fact that they want to complete their trials after phase II is down to cash not results.

“The barrier to commercial success for ICX-TRC is relatively low, being the ability to increase hair count in transplanted or thinning areas.”

There is no risk of getting to the market. There are so many people who want to use TRC.

Essentially what today’s report showed that TRC will follow a similar commercial path to vavaleta i’e no need for phase 3.

Bosley already has the set up so it makes sense for them to sell TRC.


#2

lets hope you are right…but the lack of pictures is extremely dismaying at this point.

they ought to have restored a pretty good crop of hair to a few gents before selling this, and we should be seeing that hair. I wont go and buy jackSHIIIT until I see a guy who was balding with some pretty darn good hair. Sorry, no dice.

WHERE ARE THE PICS!!!


#3

I hope you are right Nathan. They didn’t give any conclusive data to substantiate their claims. There are no pictures. No hair count.

Who spends money, time and effort to stop the development of a product that could make them billionares?

Time will tell if this is good or bad news.


#4

n/t


#5

Benji they have the photos but deciding to make them public or not at this stage has no bearing on TRC. They have shown us 1 set of pics. Remember, they have at least 3 compeitors so they need to be careful.

“All patients have now been treated in the Phase II trial of ICX-TRC, our hair regeneration product, and the results so far are promising. We have been assessing delivery variations in the trial and we have filed a patent application covering techniques which appear to improve the increase in hair count observed.”

I cant udderstand why some people are whining. If the results were not good then why on earth would they want to apply for a patent ??? If the results were disasterous then they wouldn’t careless who would copy they technology.

The fact that they want to bypass phase 3 is nothing knew. Just look back at the 2006 results. TRC will be available after phase 2 somewhere on earth which is fantastic.


#6

i hope nathan you’re right but the doubts still in my mind as the sun still in the centre of the solar system


#7

all whats requried is logical thought

Read the report properly

“ICX-TRC overcomes one of the principal drawbacks of conventional transplants which is that the outcome is limited by the amount of donor hair available. By using the Intercytex cell therapy technique almost limitless hair regeneration is possible in a less invasive procedure.”

Dont u think it would crazy to imply the above and then contradict yourself and say “TRC HAS BEEN SCRAPPED”

The great news is that all participants have been treated and secondly Phase 3 is being bypassed. The product is sellable right now hence they are seeking a partner.


#8

Intercytex & Bosley Distribution Agreement:

"With respect to the distribution agreement between Intercytex and Bosley that was previously reported on HairSite back in 2004, Dr. Kemp clarified that it is an “option” that Bosley can exercise upon completion of the phase II trial. There is no formal agreement in place at this point that will make Bosley the exclusive distributor of ICX-TRC. But Bosley will be given the first rights to negotiate."
This was old news that all of us knew back in 2004. It isn’t the end of the world. To me this implies that Intercytex is clearly looking to negotiate for a partnership (financial crutch) to help push TRC to the market. Intercytex must feel that the company can go “under” if they try to attempt phase III trials on their limited budget. They do have more than a few products in their pipeline, all putting a financial strain on their budget. Intercytex still has the potential to make alot of money, remember:

Intercytex will manufacture ICX-TRC for Europe and the US from its own manufacturing facilities. In October 2006, Intercytex was awarded a grant from the DTI to develop a robotic system with The Automation Partnership for the commercial scale production of patients’ autologous DP cells. The robotic system has an established track record in processing many different cell samples simultaneously, so that at this scale, in which large numbers of different patients’ cells are handled, all samples remain isolated throughout the multiplication process.

This all looks like the footworks for “setting up shop” so to speak. It is discouraging that they do not mention hair counts, no pictures, or even attempt to describe the hair that is growing. We need to wait and see what happens between Bosley & ICX. I think that if bosley gets the invention for “cheap” then TRC doesn’t produce great results and it needs refining. If Bosley doesn’t even offer on TRC then aderans isn’t even considering TRC a potential success. Regardless, these are exciting times! News is alot better than months & months of no news!


#9

They might not have specified the exact number of hairs but substantial = alot and limitless = an awful lot :slight_smile:


#10

» They might not have specified the exact number of hairs but substantial =
» alot and limitless = an awful lot :slight_smile:

Nathan what happened to your good news in Fall 2007 from ICX there was nothing now this. You say you know insider information about these companies ARI and Intercytex but really your all smoke and mirrors and know about as much as we do.


#11

»
» Nathan what happened to your good news in Fall 2007 from ICX there was
» nothing now this. You say you know insider information about these
» companies ARI and Intercytex but really your all smoke and mirrors and
» know about as much as we do.

Dude I still remember his “March 16th” changing the world predictions from 2006. That didn’t pan out either.


#12

if im 1 year off the mark i think i’ll be forgiven :slight_smile:

This was from 2006 so intercytex anticipated that funding will take them through to 2008 and likewise the launch of TRC in 2008. This wasnt unexpected.

A CAMBRIDGE-based company that is pioneering a hair cloning treatment for baldness will today announce plans to join London’s Alternative Investment Market in a deal valuing the business at £45 million.

Intercytex, which is also developing a treatment for wrinkles, is raising £15 million through the sale of 13.8 million new shares at 108p. The company is also placing a further £4 million worth of shares at the issue price with existing venture capital backers.

Dealings in the shares, which have already been placed by Piper Jaffray, the US investment bank, will begin on February 1.

Intercytex’s path to AIM has not been easy. Bankers pulled plans to raise £15 million last summer, in a deal that would have capitalised the company at £20 million to £30 million, after the biotech sector lost favour with City institutions. The company instead raised additional funds from its main backers, including Avlar, Merlin Biosciences and 3i.

Proceeds from the flotation will go towards funding new tests on the company’s baldness cure, ICX-TRC. The treatment, which is about to enter mid-stage clinical tests on patients, involves removing special cells from the base of the hair follicle — the cup-shaped “factory” from where individual hairs grow — and replicating them in large quantities in the laboratory.

Tens of thousands of cells are then transplanted back into the scalp, where they divide to create new follicles, which go on to generate new hair growth.

Nick Higgins, the chief executive, said that the fundraising would see the company through to at least 2008, when a version of ICX-TRC could be close to regulatory approval: “This is an elegant and sophisticated science — it’s not back-of-an-airline-magazine stuff.”


#13

no wonder that not one prediction of success made here has EVER come true. Think Gho, think Bazaan, think whoever.

To clarify your post:

  1. Intercytex DID NOT say they are bypassing phase 3 trials. We simply do not know how many trials will ultimately take place.

  2. You have no basis for saying when it will be available, where it will be available, or if it will be available.


#14

» if im 1 year off the mark i think i’ll be forgiven :slight_smile:

Just keep guessing every year. Maybe in 5-10 years, you’ll be right. :wink:

»
» This was from 2006 so intercytex anticipated that funding will take them
» through to 2008 and likewise the launch of TRC in 2008.

Where did they say they will launch in 2008?

Stop with the lies.


#15

Absolutley correct. This is getting farsical.


#16

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#17

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#18

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#19

+1

Nathan’s argumentation has always made me laugh my arse off. Nathan, do you take medications those days ? If you do drugs, diminish your doses. If you don’t do drugs, start NOW. In either case, stop basing your thoughts on the fact that what Intercytex says is the actual, unbiased, truth. De facto, there is no good or bad news. They just reported where they’re at now, and there is nothing to be particularly cheered of : very few guys have been tested, and they need prestimulation to increase hair count. Same as what was said many months ago. They never said ANYTHING about a possible commercialization schedule regarding TRC or being close to success as clearly as you might wanna see it. Stop amalgaming everything and let people have their opinions instead of preaching us some good Hm news which exists only in your fantasms.


#20

why do they want to complete both the clinical trials and commercialisation after phase 2 ?

why not just complete the clinical trials and leave it at that ? The fact that they also want to complete commercialisation tells us something.