[quote][postedby]Originally Posted by jarjarbinx[/postedby]
The DP cells that Jahoda got from hairs could have developed their hair inducing trichogenicity while in follicles, and only because they were in follicles. It could be that by culturing them they revert back to ordinary DP cells, which is also what you would probably end up with by using iSP cells to create DP cells.
DP cells may have to be produced in the follicle environment in order to acquire hair induction trichogenicity.[/quote]
Not following you there. The whole point of this new stem cell development (in the article) is that now the researchers have discovered how to create “pristine” stem cells that are completely pluripotent and have the capacity to be turned into any kind of cell… which to me, would have to include DP cells.
“Ordinary” DP cells are highly trichogenic. Those are the kind that are growing everyday in most people’s scalps.
The ones that result from culturing are highly ABNORMAL. Indeed, they’re hardly DP cells anymore. They’re just the useless progeny of multiple passages of culturing DP cells.
Also, what you said is kind of circular reasoning. If you need a follicle environment to create useful DP cells, where do you get the healthy follicles to do it, if you don’t have them on your head?
You could say you grow them in a petri dish. But with what? Part of what you need is healthy DP cells.