Home | News | Find a Doctor | Ask a Question | Free

Nizoral IS a DHT blocker


#1

Nizoral is a DHT blocker. Seems to be some debate on this.

See the list of Anti-Androgen drugs here: http://en.wikipedia.org/wiki/Antiandrogen

DHT is an Androgen:
"Dihydrotestosterone (DHT): a metabolite of testosterone, and a more potent androgen than testosterone in that it binds more strongly to androgen receptors"


#2

» Nizoral is a DHT blocker. Seems to be some debate on this.
»
» See the list of Anti-Androgen drugs here:
» http://en.wikipedia.org/wiki/Antiandrogen
»
» DHT is an Androgen:
» “Dihydrotestosterone (DHT): a metabolite of testosterone, and a more
» potent androgen than testosterone in that it binds more strongly to
» androgen receptors”
» http://en.wikipedia.org/wiki/Androgen

Ketoconazole is pretty non-specific on it’s impact on androgens. I believe this is part of the reason it works better than substances that target DHT only.


#3

Nizoral is not regulated by the FDA so when it was originally provided to the consumer, there were no clinical trials completed to establish its efficacy. The results vary quite a bit between patients. If it works favorably, by all means keep using it.


#4

» Nizoral is not regulated by the FDA so when it was originally provided to
» the consumer, there were no clinical trials completed to establish its
» efficacy. The results vary quite a bit between patients. If it works
» favorably, by all means keep using it.

It is prescribed and approved by the FDA as an anti-fungal; in the US the 2% concentration required a script.

The fact the WHO lists Ketoconazole as a potent chemical with a potentially serious impact on human endocrinology is a completely different thing.

The first is why many people don’t understand how Nizoral can impact hairloss, the second clearly explains it’s mechanism (e.g. thru action on all androgens). Interestingly Nizoral impacts Adrenal as well as HPTA endocrinology; this is part of the reason I believe it works so well for people that may not react to simple DHT treatments.


#5

» » Nizoral is not regulated by the FDA so when it was originally provided
» to
» » the consumer, there were no clinical trials completed to establish its
» » efficacy. The results vary quite a bit between patients. If it works
» » favorably, by all means keep using it.
»
» It is prescribed and approved by the FDA as an anti-fungal; in the US the
» 2% concentration required a script.
»
» The fact the WHO lists Ketoconazole as a potent chemical with a
» potentially serious impact on human endocrinology is a completely
» different thing.
»
» The first is why many people don’t understand how Nizoral can impact
» hairloss, the second clearly explains it’s mechanism (e.g. thru action on
» all androgens). Interestingly Nizoral impacts Adrenal as well as HPTA
» endocrinology; this is part of the reason I believe it works so well for
» people that may not react to simple DHT treatments.

where do you buy Nizoral cream from? link?


#6

» It is prescribed and approved by the FDA as an anti-fungal; in the US the
» 2% concentration required a script.
» The fact the WHO lists Ketoconazole as a potent chemical with a
» potentially serious impact on human endocrinology is a completely
» different thing.The first is why many people don’t understand how Nizoral can impact
» hairloss, the second clearly explains it’s mechanism (e.g. thru action on
» all androgens). Interestingly Nizoral impacts Adrenal as well as HPTA
» endocrinology; this is part of the reason I believe it works so well for
» people that may not react to simple DHT treatments.

gc1961, how do you make your Ketoconazole topical?
i found the ingredients in Nizoral cream as:
Nizoral cream contain the synthetic broad-spectrum antifungal agent, ketoconazole. Each gram contains 20 mg ketoconazole. The cream formulation consist of propylene glycol, stearyl alcohol, cetyl alcohol, sorbitan stearate, polysorbate, isoproply myristate, sodium sulphite and purified water.
from this link:
http://cgi.ebay.com/2x20g-NIZORAL-CREAM-where-to-buy-cheaper-cost-price_W0QQitemZ170115192547QQihZ007QQcategoryZ3193QQrdZ1QQssPageNameZWD1VQQcmdZViewItem

which contains a lot of alcohol substance. my skin is very sensitive to alcohol. thanks for any info.


#7

» » It is prescribed and approved by the FDA as an anti-fungal; in the US
» the
» » 2% concentration required a script.
» » The fact the WHO lists Ketoconazole as a potent chemical with a
» » potentially serious impact on human endocrinology is a completely
» » different thing.The first is why many people don’t understand how
» Nizoral can impact
» » hairloss, the second clearly explains it’s mechanism (e.g. thru action
» on
» » all androgens). Interestingly Nizoral impacts Adrenal as well as HPTA
» » endocrinology; this is part of the reason I believe it works so well
» for
» » people that may not react to simple DHT treatments.
»
» gc1961, how do you make your Ketoconazole topical?
» i found the ingredients in Nizoral cream as:
» Nizoral cream contain the synthetic broad-spectrum antifungal agent,
» ketoconazole. Each gram contains 20 mg ketoconazole. The cream
» formulation consist of propylene glycol, stearyl alcohol, cetyl alcohol,
» sorbitan stearate, polysorbate, isoproply myristate, sodium sulphite and
» purified water.
» from this link:
» http://cgi.ebay.com/2x20g-NIZORAL-CREAM-where-to-buy-cheaper-cost-price_W0QQitemZ170115192547QQihZ007QQcategoryZ3193QQrdZ1QQssPageNameZWD1VQQcmdZViewItem
»
» which contains a lot of alcohol substance. my skin is very sensitive to
» alcohol. thanks for any info.

Mine is simply 20mg Keto, purified water and dermovan cream.


#8

» » » It is prescribed and approved by the FDA as an anti-fungal; in the US
» » the
» » » 2% concentration required a script.
» » » The fact the WHO lists Ketoconazole as a potent chemical with a
» » » potentially serious impact on human endocrinology is a completely
» » » different thing.The first is why many people don’t understand how
» » Nizoral can impact
» » » hairloss, the second clearly explains it’s mechanism (e.g. thru
» action
» » on
» » » all androgens). Interestingly Nizoral impacts Adrenal as well as HPTA
» » » endocrinology; this is part of the reason I believe it works so well
» » for
» » » people that may not react to simple DHT treatments.
» »
» » gc1961, how do you make your Ketoconazole topical?
» » i found the ingredients in Nizoral cream as:
» » Nizoral cream contain the synthetic broad-spectrum antifungal agent,
» » ketoconazole. Each gram contains 20 mg ketoconazole. The cream
» » formulation consist of propylene glycol, stearyl alcohol, cetyl
» alcohol,
» » sorbitan stearate, polysorbate, isoproply myristate, sodium sulphite
» and
» » purified water.
» » from this link:
» »
» http://cgi.ebay.com/2x20g-NIZORAL-CREAM-where-to-buy-cheaper-cost-price_W0QQitemZ170115192547QQihZ007QQcategoryZ3193QQrdZ1QQssPageNameZWD1VQQcmdZViewItem
» »
» » which contains a lot of alcohol substance. my skin is very sensitive to
» » alcohol. thanks for any info.
»
» Mine is simply 20mg Keto, purified water and dermovan cream.

ok thanks. but do you buy the ingredients individually from somewhere and mix them up? or you buy it already made? WHERE do you order it from (website link)? thanks mate.


#9

the_one,

click on that ebay link and look closer. “ketoconazole 20mg per 1G”. I believe that IS nizoral 2% cream. That’s exactly where I bought my nizoral cream from…ebay. That’s the exact same product I bought too.

Perry

http://cgi.ebay.com/2x20g-NIZORAL-CREAM-where-to-buy-cheaper-cost-price_W0QQitemZ170115192547QQihZ007QQcategoryZ3193QQrdZ1QQssPageNameZWD1VQQcmdZViewItem
» » »
» » » which contains a lot of alcohol substance. my skin is very sensitive
» to
» » » alcohol. thanks for any info.
» »
» » Mine is simply 20mg Keto, purified water and dermovan cream.
»
» ok thanks. but do you buy the ingredients individually from somewhere and
» mix them up? or you buy it already made? WHERE do you order it from
» (website link)? thanks mate.


#10

that seems to be the standard way of listing 2 percent is by that ratio


#11

» that seems to be the standard way of listing 2 percent is by that ratio

thanks guys. but don’t you get skin irritation and rushes because of alcohol content?


#12

» » that seems to be the standard way of listing 2 percent is by that ratio
»
» thanks guys. but don’t you get skin irritation and rushes because of
» alcohol content?

i suppose anything could cause a reaction with some people

I have not noticed boardmembers complaining of that problem,


#13

I don’t get any rash from it at all. I guess it depends on the person though.


#14

gc1961, do you think nizoral might though impact the sex hormonal balance and induce a slight feedback to the pituitary gland??


#15

who cares. doesn’t grow hair.


#16

» who cares. doesn’t grow hair.

yes gc1961 pics are fake right and the japanese study pics are fake

and all those new hairs in my frontal temple and hairline are just my imagination, ah ok thanks for your expertise in this matter


#17

» gc1961, do you think nizoral might though impact the sex hormonal balance
» and induce a slight feedback to the pituitary gland??

Use is ONLY as a topical and you should be ok; should be far less effect than using systemic drugs like Finasteride or Dutasteride.

Nizoral (Ketoconazole) impacts a broader set of hormones (DHEA, Estrogen, etc) so should only be used topically.


#18

If you look at the recent Japan nizoral study they say it works by suppressing the androgen receptor and also by being a non androgen related growth stimulator. So its not blocking DHT like propecia does.

» » gc1961, do you think nizoral might though impact the sex hormonal
» balance
» » and induce a slight feedback to the pituitary gland??
»
» Use is ONLY as a topical and you should be ok; should be far less effect
» than using systemic drugs like Finasteride or Dutasteride.
»
» Nizoral (Ketoconazole) impacts a broader set of hormones (DHEA, Estrogen,
» etc) so should only be used topically.


#19

» If you look at the recent Japan nizoral study they say it works by
» suppressing the androgen receptor and also by being a non androgen related
» growth stimulator. So its not blocking DHT like propecia does.

“suppressing the androgen receptor” = blocking DHT.

DHT is an androgen. Supressing the receptor is stopping it from being receptive to androgens (DHT), ie. blocking androgens (DHT).


#20

» » If you look at the recent Japan nizoral study they say it works by
» » suppressing the androgen receptor and also by being a non androgen
» related
» » growth stimulator. So its not blocking DHT like propecia does.
»
» “suppressing the androgen receptor” = blocking DHT.
»
» DHT is an androgen. Supressing the receptor is stopping it from being
» receptive to androgens (DHT), ie. blocking androgens (DHT).

agreed that is whey they are called DHT blockers,