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@MikeWalters


#1

On what day did your skin start peeling after the multi-layered peel?
I’m a bit vague about when to deem it ‘Day One’ for purposes of application of the topicals. I’ve previously began applying topicals on about Day 3 or 4 post wounding after the skin shows signs of epithelization and maybe a little peeling.
I need to make a solid decision on when to apply the topicals and when to cease wnt inhibition and begin boosting.
For instance, I could orally inhibit wnt with quercetin and curcumin right from Day 1. This will also supplement the EGF inhibition.
Then on Day 4, I could begin applying the topical gefit and also a topical wnt inhibitor made from quercetin and curcumin.
On Day 10 I could cease the oral and topical wnt inhibition and just continue with the gefit until about Day 18.

The only thing I’m worried about is the possibility of the embryonic window being unique to the individual and also possibly influenced by exact depth of wound. These variables could possibly displace the window to an earlier or later point. What do you think?

P.S. I’m not asking because I’ve received your topical. I don’t expect to get that before the New Year due to the increased volume of post over the festive period.


#2

» On what day did your skin start peeling after the multi-layered peel?
» I’m a bit vague about when to deem it ‘Day One’ for purposes of
» application of the topicals. I’ve previously began applying topicals on
» about Day 3 or 4 post wounding after the skin shows signs of epithelization
» and maybe a little peeling.
» I need to make a solid decision on when to apply the topicals and when to
» cease wnt inhibition and begin boosting.
» For instance, I could orally inhibit wnt with quercetin and curcumin right
» from Day 1. This will also supplement the EGF inhibition.
» Then on Day 4, I could begin applying the topical gefit and also a topical
» wnt inhibitor made from quercetin and curcumin.
» On Day 10 I could cease the oral and topical wnt inhibition and just
» continue with the gefit until about Day 18.
»
» The only thing I’m worried about is the possibility of the embryonic
» window being unique to the individual and also possibly influenced by exact
» depth of wound. These variables could possibly displace the window to an
» earlier or later point. What do you think?
»
» P.S. I’m not asking because I’ve received your topical. I don’t expect to
» get that before the New Year due to the increased volume of post over the
» festive period.

I think I started peeling 3-4 days after. When to do EGFR inhibition is still a ?? to me so I started @ day 1. There is no mention of it being detrimental if started too early right? – and you do have enough for that. BTW, I applied getfitnib in early AM and @ 2pm and rinse off b4 I sleep with just water. I applied 2x’s a day in other words. Didn’t somebody mention that curcumin wouldn’t be a good inhibitor for some reason that I just can’t think of right now? I would definitely use quercetin, I’ve never inhibited wnt in either of my trys so it would be interesting to see what u get from this. Your plan sounds like a solid one. Look into curcumin for wnt inhibition, I’m not sure if you wnat to use that. Do u still have any lithium left? If u do, maybe from days 11-18 this should be applied, maybe 2 hours apart from getfitnib. I would join u on this one but it is still too early since my last run and I am seeing results. I’m guessing by March 2009, I hope to have a heathy looking harline to share with everyone here.:smiley:


#3

» I think I started peeling 3-4 days after. When to do EGFR inhibition is
» still a ?? to me so I started @ day 1. There is no mention of it being
» detrimental if started too early right? – and you do have enough for
» that. BTW, I applied getfitnib in early AM and @ 2pm and rinse off b4 I
» sleep with just water. I applied 2x’s a day in other words. Didn’t
» somebody mention that curcumin wouldn’t be a good inhibitor for some reason
» that I just can’t think of right now? I would definitely use quercetin,
» I’ve never inhibited wnt in either of my trys so it would be interesting to
» see what u get from this. Your plan sounds like a solid one. Look into
» curcumin for wnt inhibition, I’m not sure if you wnat to use that. Do u
» still have any lithium left? If u do, maybe from days 11-18 this should be
» applied, maybe 2 hours apart from getfitnib. I would join u on this one
» but it is still too early since my last run and I am seeing results. I’m
» guessing by March 2009, I hope to have a heathy looking harline to share
» with everyone here.:smiley:

Sounds good Mike. I actually received your package to day. I wasn’t expecting it until New Year but I can get started tomorrow. I would have started today but I went on an all day drinking session the day before and I’m feeling like crap as I write this.
Nice touch with the Christmas wrapping BTW. To get my hair back would be the best present I’ve ever had. Cheers m8 and I’ll keep you updated. I’ve also emailed you.


#4

» » I think I started peeling 3-4 days after. When to do EGFR inhibition is
» » still a ?? to me so I started @ day 1. There is no mention of it being
» » detrimental if started too early right? – and you do have enough for
» » that. BTW, I applied getfitnib in early AM and @ 2pm and rinse off b4
» I
» » sleep with just water. I applied 2x’s a day in other words. Didn’t
» » somebody mention that curcumin wouldn’t be a good inhibitor for some
» reason
» » that I just can’t think of right now? I would definitely use
» quercetin,
» » I’ve never inhibited wnt in either of my trys so it would be interesting
» to
» » see what u get from this. Your plan sounds like a solid one. Look
» into
» » curcumin for wnt inhibition, I’m not sure if you wnat to use that. Do
» u
» » still have any lithium left? If u do, maybe from days 11-18 this should
» be
» » applied, maybe 2 hours apart from getfitnib. I would join u on this
» one
» » but it is still too early since my last run and I am seeing results.
» I’m
» » guessing by March 2009, I hope to have a heathy looking harline to
» share
» » with everyone here.:smiley:
»
» Sounds good Mike. I actually received your package to day. I wasn’t
» expecting it until New Year but I can get started tomorrow. I would have
» started today but I went on an all day drinking session the day before and
» I’m feeling like crap as I write this.
» Nice touch with the Christmas wrapping BTW. To get my hair back would be
» the best present I’ve ever had. Cheers m8 and I’ll keep you updated. I’ve
» also emailed you.

Excellent news! Good luck!


#5

» Nice touch with the Christmas wrapping BTW. To get my hair back would be
» the best present I’ve ever had. Cheers m8 and I’ll keep you updated. I’ve
» also emailed you.

Wawww …I think you guys are falling in love :smiley:


#6

» » On what day did your skin start peeling after the multi-layered peel?
» » I’m a bit vague about when to deem it ‘Day One’ for purposes of
» » application of the topicals. I’ve previously began applying topicals on
» » about Day 3 or 4 post wounding after the skin shows signs of
» epithelization
» » and maybe a little peeling.
» » I need to make a solid decision on when to apply the topicals and when
» to
» » cease wnt inhibition and begin boosting.
» » For instance, I could orally inhibit wnt with quercetin and curcumin
» right
» » from Day 1. This will also supplement the EGF inhibition.
» » Then on Day 4, I could begin applying the topical gefit and also a
» topical
» » wnt inhibitor made from quercetin and curcumin.
» » On Day 10 I could cease the oral and topical wnt inhibition and just
» » continue with the gefit until about Day 18.
» »
» » The only thing I’m worried about is the possibility of the embryonic
» » window being unique to the individual and also possibly influenced by
» exact
» » depth of wound. These variables could possibly displace the window to
» an
» » earlier or later point. What do you think?
» »
» » P.S. I’m not asking because I’ve received your topical. I don’t expect
» to
» » get that before the New Year due to the increased volume of post over
» the
» » festive period.
»
»
» I think I started peeling 3-4 days after. When to do EGFR inhibition is
» still a ?? to me so I started @ day 1. There is no mention of it being
» detrimental if started too early right? – and you do have enough for
» that. BTW, I applied getfitnib in early AM and @ 2pm and rinse off b4 I
» sleep with just water. I applied 2x’s a day in other words. Didn’t
» somebody mention that curcumin wouldn’t be a good inhibitor for some reason
» that I just can’t think of right now? I would definitely use quercetin,
» I’ve never inhibited wnt in either of my trys so it would be interesting to
» see what u get from this. Your plan sounds like a solid one. Look into
» curcumin for wnt inhibition, I’m not sure if you wnat to use that. Do u
» still have any lithium left? If u do, maybe from days 11-18 this should be
» applied, maybe 2 hours apart from getfitnib. I would join u on this one
» but it is still too early since my last run and I am seeing results. I’m
» guessing by March 2009, I hope to have a heathy looking harline to share
» with everyone here.:smiley:
Mikewalters, do you really think you might get a full head of hair with your procedure? If you are getting decent results, then we can expect Follica to have a very good success.


#7

»
»
» Wawww …I think you guys are falling in love :smiley:

LOL!!!


#8

» » » On what day did your skin start peeling after the multi-layered peel?
» » » I’m a bit vague about when to deem it ‘Day One’ for purposes of
» » » application of the topicals. I’ve previously began applying topicals
» on
» » » about Day 3 or 4 post wounding after the skin shows signs of
» » epithelization
» » » and maybe a little peeling.
» » » I need to make a solid decision on when to apply the topicals and
» when
» » to
» » » cease wnt inhibition and begin boosting.
» » » For instance, I could orally inhibit wnt with quercetin and curcumin
» » right
» » » from Day 1. This will also supplement the EGF inhibition.
» » » Then on Day 4, I could begin applying the topical gefit and also a
» » topical
» » » wnt inhibitor made from quercetin and curcumin.
» » » On Day 10 I could cease the oral and topical wnt inhibition and just
» » » continue with the gefit until about Day 18.
» » »
» » » The only thing I’m worried about is the possibility of the embryonic
» » » window being unique to the individual and also possibly influenced by
» » exact
» » » depth of wound. These variables could possibly displace the window to
» » an
» » » earlier or later point. What do you think?
» » »
» » » P.S. I’m not asking because I’ve received your topical. I don’t
» expect
» » to
» » » get that before the New Year due to the increased volume of post over
» » the
» » » festive period.
» »
» »
» » I think I started peeling 3-4 days after. When to do EGFR inhibition
» is
» » still a ?? to me so I started @ day 1. There is no mention of it being
» » detrimental if started too early right? – and you do have enough for
» » that. BTW, I applied getfitnib in early AM and @ 2pm and rinse off b4
» I
» » sleep with just water. I applied 2x’s a day in other words. Didn’t
» » somebody mention that curcumin wouldn’t be a good inhibitor for some
» reason
» » that I just can’t think of right now? I would definitely use
» quercetin,
» » I’ve never inhibited wnt in either of my trys so it would be interesting
» to
» » see what u get from this. Your plan sounds like a solid one. Look
» into
» » curcumin for wnt inhibition, I’m not sure if you wnat to use that. Do
» u
» » still have any lithium left? If u do, maybe from days 11-18 this should
» be
» » applied, maybe 2 hours apart from getfitnib. I would join u on this
» one
» » but it is still too early since my last run and I am seeing results.
» I’m
» » guessing by March 2009, I hope to have a heathy looking harline to
» share
» » with everyone here.:smiley:
» Mikewalters, do you really think you might get a full head of hair with
» your procedure? If you are getting decent results, then we can expect
» Follica to have a very good success.

I’m keeping my fingers crossed! All I can do is wait and report. I will definitely show photos if it gets good enough. I would say March 2009 I would know for sure. The hairs definitely popped up all over, the question is whether or not it will grow out and become normal hairs.


#9

»
» I’m keeping my fingers crossed! All I can do is wait and report. I will
» definitely show photos if it gets good enough. I would say March 2009 I
» would know for sure. The hairs definitely popped up all over, the question
» is whether or not it will grow out and become normal hairs.

I think someone mentioned that curcumin is too large molecularly to be of any use topically, Of course, the same might be said of quercetin and apple polyphenols too. With this in mind, during the wnt inhibition period, I will be taking apple polyphenols, curcumin and quercetin as well as green tea. I will take these all ORALLY until about Day 8 when I will cease wnt inhibition and begin boosting via topical lithium.
I’ve just done the peel and it hurt like a bitch! Four consecutive passes of tca 30%. Visibly, it looks very underwhelming. No redness really and it just feels a little tender in places. I’m going to begin topical tacro application immediately and maybe start with the topical gefit donated by Mike Walters tomorrow.


#10

Mike,
From the start of this procedure, did you wash your hair or allow any water to touch the wound? I would love to try this again on my temples but I can’t go without washing my hair. I am wondering if there some type of bandage I could apply to the dermabraded area that would prevent water from entering… Also, do you think water touching the wounded areas makes a difference? I generally wash my hair daily with nizoral.


#11

» Mike,
» From the start of this procedure, did you wash your hair or allow any
» water to touch the wound? I would love to try this again on my temples but
» I can’t go without washing my hair. I am wondering if there some type of
» bandage I could apply to the dermabraded area that would prevent water from
» entering… Also, do you think water touching the wounded areas makes a
» difference? I generally wash my hair daily with nizoral.

I find it difficult to believe that water on it’s own would affect the process. But you certainly shouldn’t rub it during the epithelization/peeling stage. My biggest fear is if I start smelling like a rotten cabbage due to the dmso. But I’m prepared to suffer the few days of exposure in work in the New Year.


#12

» My biggest fear is if I start smelling like a
» rotten cabbage due to the dmso. But I’m prepared to suffer the few days of
» exposure in work in the New Year.

Baccy,

I heard from some other places that really “clean” 99.9%+ pharmaceutical grade DMSO should not make you particularly smelly. Only the industrial type, lower grade DMSO supposedly does that. The smell would be the result of the contaminants in the bad DMSO being pushed into your body. Have you considered trying another brand/type of DMSO?

I bought a 99.9% DMSO from Nature’s Gift, but I have not tried it yet, so I can’t vouch for it.

/p


#13

Update: I’ve just done another pass with the 30% peel. That makes 5 applications in all. That should definitely be sufficient and area covered is all over the top of my scalp, hairline area and everything down to where my monk hairline begins on the side of my head. Scalp is nice and red and shiny now. Hurt like a btd but like Mike, I’ve got confidence in this procedure.


#14

» »
» » I’m keeping my fingers crossed! All I can do is wait and report. I
» will
» » definitely show photos if it gets good enough. I would say March 2009
» I
» » would know for sure. The hairs definitely popped up all over, the
» question
» » is whether or not it will grow out and become normal hairs.
»
» I think someone mentioned that curcumin is too large molecularly to be of
» any use topically, Of course, the same might be said of quercetin and apple
» polyphenols too. With this in mind, during the wnt inhibition period, I
» will be taking apple polyphenols, curcumin and quercetin as well as green
» tea. I will take these all ORALLY until about Day 8 when I will cease wnt
» inhibition and begin boosting via topical lithium.
» I’ve just done the peel and it hurt like a bitch! Four consecutive passes
» of tca 30%. Visibly, it looks very underwhelming. No redness really and it
» just feels a little tender in places. I’m going to begin topical tacro
» application immediately and maybe start with the topical gefit donated by
» Mike Walters tomorrow.

“Underwhelming” – that was the way I felt when I did 4 passes on my 2nd try. I did another 2 peels a say after. I don’t you need to do that. Now u know what I mean when I say 1-2 is not enough?


#15

» » My biggest fear is if I start smelling like a
» » rotten cabbage due to the dmso. But I’m prepared to suffer the few days
» of
» » exposure in work in the New Year.
»
» Baccy,
»
» I heard from some other places that really “clean” 99.9%+ pharmaceutical
» grade DMSO should not make you particularly smelly. Only the industrial
» type, lower grade DMSO supposedly does that. The smell would be the result
» of the contaminants in the bad DMSO being pushed into your body. Have you
» considered trying another brand/type of DMSO?
»
» I bought a 99.9% DMSO from Nature’s Gift, but I have not tried it yet, so
» I can’t vouch for it.
»
» /p

I used 99.9% on my solution and the one I sent baccy.:slight_smile:


#16

»» I bought a 99.9% DMSO from Nature’s Gift, but I have not tried it yet, so
» I can’t vouch for it.
»
» /p

I’ve just checked. That is the EXACT brand I have. 99.9% and Nature’s Gift. It still made me stink but I applied it pure to the scalp.


#17

» I used 99.9% on my solution and the one I sent baccy.:slight_smile:

What brand do you use? Where did you buy it?

Merry Xmas!


#18

while i am waiting for my peel solution to arrive, sand papered a two inch area at the temple ( deep enough it bled)and will wait 4 days before applying topicals. I washed my hair will Nizoral and will continue to wash daily. I am going to try Lithium O again mixed with DMSO after 4 days.


#19

» while i am waiting for my peel solution to arrive, sand papered a two inch
» area at the temple ( deep enough it bled)and will wait 4 days before
» applying topicals. I washed my hair will Nizoral and will continue to wash
» daily. I am going to try Lithium O again mixed with DMSO after 4 days.

I’m following what Mike did and that is applying the topical gefit he provided right from Day 1. It’s hard to say when this damned window is but it’s best not to miss it. He provided a 40ml solution so in theory, I’ve got enough for 20 days application applying 1ml twice a day. Worryingly though, it looks like there isn’t going to be enough mixture for the duration although I’m telling myself that it’s just an illusion.
This is Day 3 and my scalp is epithelizing nicely. The skin is dry, numb and wrinkly but hasn’t started peeling yet. I’m not even sure that the topical applications are getting through the damaged skin but like Mike, I’m afraid of missing the window.
As far as wnt inhibition/boosting is concerned, I’ve been taking apple polys, curcumin and quercetin internally to initially inhibit wnt. I don’t want to inhibit it too long; just for the epithelization stage and then I will boost with topical lithium. If I inhibit for too long, it will eradicate any chance of neogenesis/rejuvenation so I’m not risking inhibiting for 10 days. The ten day figure came from mice and human skin epithelizes more quickly. In the human skin test (Experiment 7 in the patent), HF cells were present at Day 7 so I intend to cease inhibition maybe today. I may start applying the topical lith tomorrow, separately from the topical gefit. I have also been applying topical tacro from Day 1 for the immunosuppression aspect and I have been taking internal diphenhydramine for the anti-histamine aspect.
As always, I shall keep you all apprised.


#20

It’s now Day 5 and although the scalp hasn’t peeled yet, the entire area is rippling as fresh skin forms beneath. I reckon it will start peeling on Day 6 or 7. This seems to be the most uniform and comprehensive of my wounding experiments as it looks like the whole scalp is going to peel off in one piece. I suppose it’s taking longer to peel due to the fact that I did 5 consecutive peels. That’s probably several layers of the epidermis. I’ve been applying topical gefit from Day 1 and from Day 3 onwards, I introduced hair growth factors consisting of the noggin peptide (we all know about that one), keramin 2 (inhibits DKK1 and hence upregulates wnt) and Prohairin B4. I obtained this from a guy on another forum who bought in bulk from Caragen, a Korean biotech firm specialising in growth factors. I’m also applying topical tacro for immunosuppression and taking diphenhydramine tabs at nighttime for anti-histamine. I will commence with topical lithium today. All topicals are applied at different times of the day.
As it hasn’t peeled yet, I may be wasting time and money applying topicals as I don’t know whether they are getting through the damaged layers of skin. But I’d hate to miss the window so I’m doing it anyway. If it peels on Day 8, I will have enough topical gefit to apply for a further 12 days after the peel. I’m hoping that this will cover the window.