any of you two ?
Sorry, for my insistence, but i am thinking a lot of getting a HT, but at the same time Histogen looks promising in my eyes.
what do you believe?
what do you suggest?
I don’t expect from histogen that they’ll able to wake up all my sleeping follicle, this sounds too good to be possible, however to plan a strategy we need to know almost how many chance we have to see the procedure hit the market in the next 1-2 years, and all depend on how much you can and want to wait, personally i won’t wait more than 2 years, so i’ll get an HT for sure in the next 2y, at least after that I’ll choose aderans or histogen the year after that date to boost density upon my head, but my hairline have to come back to the owner
we’re talking about the goal they can achieve but there are realistic info about how many years they can need to end their research? It should be cool if in 2013 the procedure will be avaiable, considering we’re near 2011 atm
» what if someone has had a HT on that bald scalp?.
» obviously during HT, the natural pattern is being destroyed right?
» The ‘‘doctor’’ will place the grafts randomly, destroying at the same time
» the natural pattern.
» If Histogen doesn’t create new follicles, all Htpatients will face
» unexpected results after Histogen’s injections.
» If this is the case , that means that if someone really believes that
» Histogen will work sometime in the future, must re-think to go for a HT
» now.
» what do you think?
What (or who) brought you to all these thoughts?
Actually, there is no need to read any boring and/or complicated medical science or something else, because sometimes is something just intuitive.
And sometimes can give you just carefully reading of short informations many answers (or not):
I think it has the potential to wake up 95-100% of your dormant follicles. This trail was the minimum dosage and only ONE injection in a large space, the amount of area that was affected by one injection and how much growth it stimulated is actually incredible. Think about it, one tiny injection added that many hairs plus made pretty much all the hair terminal looking at the pictures, the hair on the right side always looks thicker and darker and all of this is from one minimal dose injection over a pretty large space. Think about multiple injections of a higher dose over the same space, could potentially revitalize all your follicles and give you a patch of “teenage density” hair.
That’s just my two cents. I’m clearly being optimistic but considering these results are from this trail that was meant to just test efficacy with a small dose and one injection, this is pretty incredible.
-Eric
Hey dont be so cokky 
lets assume 70% to be more realistic at first cause there is always a space upwards
And you are right the injection did something amazing to hiy donor or the area around his bald spot, his hair looks younger in some strange kind of way
Teenage density yes is absolutely possible cause you are right.
But we have to see this one was just a test injection and the results well lets face it are pretty good. And most important the hair is dht resistant.
Even if your hair will fall out around 15 years later after thre treatment, who cares, because then we will have plenty of possibilities to get our hair back.
The only thing which really sucks right now, i speak for myself i think, is the waiting time and iam not conclusive if i wann have a frontal restoration with the maximum density possible or to wait there als.
But iam glad i dont have to care for my crown any more, cause this little piece of shot sucks grafts like hell
Anyway thanks Eric for a very nice argumentation here
» I think it has the potential to wake up 95-100% of your dormant follicles.
» This trail was the minimum dosage and only ONE injection in a large space,
» the amount of area that was affected by one injection and how much growth
» it stimulated is actually incredible. Think about it, one tiny injection
» added that many hairs plus made pretty much all the hair terminal looking
» at the pictures, the hair on the right side always looks thicker and darker
» and all of this is from one minimal dose injection over a pretty large
» space. Think about multiple injections of a higher dose over the same
» space, could potentially revitalize all your follicles and give you a patch
» of “teenage density” hair.
»
» That’s just my two cents. I’m clearly being optimistic but considering
» these results are from this trail that was meant to just test efficacy with
» a small dose and one injection, this is pretty incredible.
»
» -Eric
» » furthermore, virtually every treatment and drug has side-effects as i’m
» » certain Histogen will have too… side effects do not mean the immediate
» » termination of clinical trails… it all depends on the severity of the
» » side-effects.
»
» histogen works like aderans with your own stem cells or i’m wrong on this?
No, Histogen just uses growth factors. They don’t need to take a biopsy of the back of your head. This is a big plus. This reduces costs dramatically. The product is universal, can be injected to anyone, while ARI needs to make a product specifically for you (they culture your cells).
unfortunately, its impossible to make reliable predictions.
Back in 1998, people thought that HM was 1 year away.
» any of you two ?
»
» Sorry, for my insistence, but i am thinking a lot of getting a HT, but at
» the same time Histogen looks promising in my eyes.
»
» what do you believe?
»
» what do you suggest?
In 1998 we never had the infromation from today nor the technologie. In 1998 FUE was just in the early beginnings.
And nobody would have said HM is 1 year away
Or do you have proof and link for your claims, we are all waiting
» unfortunately, its impossible to make reliable predictions.
» Back in 1998, people thought that HM was 1 year away.
»
» » any of you two ?
» »
» » Sorry, for my insistence, but i am thinking a lot of getting a HT, but
» at
» » the same time Histogen looks promising in my eyes.
» »
» » what do you believe?
» »
» » what do you suggest?
» In 1998 we never had the infromation from today nor the technologie. In
» 1998 FUE was just in the early beginnings.
»
» And nobody would have said HM is 1 year away
»
» Or do you have proof and link for your claims, we are all waiting
are you asking me for links? Are you going to post your ARI email? Or the Gho patient you saw with your own eyes (with donor regrowth)?
yes, I have links but I will post them in due time.
»
» » unfortunately, its impossible to make reliable predictions.
» » Back in 1998, people thought that HM was 1 year away.
» »
» » » any of you two ?
» » »
» » » Sorry, for my insistence, but i am thinking a lot of getting a HT,
» but
» » at
» » » the same time Histogen looks promising in my eyes.
» » »
» » » what do you believe?
» » »
» » » what do you suggest?
I hoe those links are not tampered with or you left important sentence frgments like “We can do HM in a year… if we can overcome some serious problems” ibet you would cut the last part
» » In 1998 we never had the infromation from today nor the technologie. In
» » 1998 FUE was just in the early beginnings.
» »
» » And nobody would have said HM is 1 year away
» »
» » Or do you have proof and link for your claims, we are all waiting
»
» are you asking me for links? Are you going to post your ARI email? Or the
» Gho patient you saw with your own eyes (with donor regrowth)?
» yes, I have links but I will post them in due time.
»
»
» »
» » » unfortunately, its impossible to make reliable predictions.
» » » Back in 1998, people thought that HM was 1 year away.
» » »
» » » » any of you two ?
» » » »
» » » » Sorry, for my insistence, but i am thinking a lot of getting a HT,
» » but
» » » at
» » » » the same time Histogen looks promising in my eyes.
» » » »
» » » » what do you believe?
» » » »
» » » » what do you suggest?
» No, Histogen just uses growth factors. They don’t need to take a biopsy of
» the back of your head. This is a big plus. This reduces costs dramatically.
» The product is universal, can be injected to anyone, while ARI needs to
» make a product specifically for you (they culture your cells).
thanks for the info, now I know that… this is a surprise for me, how can a “simply” growth factor be better than your stem cells? I wonder if the hair will be DHT resistant and will have a natural life for years as my hair does in the donor
Well, if they manage to bring back 70%+ of hair you are pretty much covered… Don’t they say people don’t even realize they are losing hair until they’ve lost 50% from the scalp… I’m not being cokky, I don’t work for Histogen but I do believe they have the chance to bring 100% back with more injections and higher doses, we shall see, lets keep our fingers crossed Leeroy and hope it does (knock on wood, make wishes, pray, hope for the best…). Anyway man, it’s nice to see some real progress.
» Hey dont be so cokky lets assume 70% to be more realistic at first
» cause there is always a space upwards
»
» And you are right the injection did something amazing to hiy donor or the
» area around his bald spot, his hair looks younger in some strange kind of
» way
»
» Teenage density yes is absolutely possible cause you are right.
»
» But we have to see this one was just a test injection and the results well
» lets face it are pretty good. And most important the hair is dht
» resistant.
»
» Even if your hair will fall out around 15 years later after thre
» treatment, who cares, because then we will have plenty of possibilities to
» get our hair back.
»
» The only thing which really sucks right now, i speak for myself i think,
» is the waiting time and iam not conclusive if i wann have a frontal
» restoration with the maximum density possible or to wait there als.
»
» But iam glad i dont have to care for my crown any more, cause this little
» piece of shot sucks grafts like hell
»
» Anyway thanks Eric for a very nice argumentation here
»
» » I think it has the potential to wake up 95-100% of your dormant
» follicles.
» » This trail was the minimum dosage and only ONE injection in a large
» space,
» » the amount of area that was affected by one injection and how much
» growth
» » it stimulated is actually incredible. Think about it, one tiny
» injection
» » added that many hairs plus made pretty much all the hair terminal
» looking
» » at the pictures, the hair on the right side always looks thicker and
» darker
» » and all of this is from one minimal dose injection over a pretty large
» » space. Think about multiple injections of a higher dose over the same
» » space, could potentially revitalize all your follicles and give you a
» patch
» » of “teenage density” hair.
» »
» » That’s just my two cents. I’m clearly being optimistic but considering
» » these results are from this trail that was meant to just test efficacy
» with
» » a small dose and one injection, this is pretty incredible.
» »
» » -Eric
I agree with you GoGiants. Histogen could be THE answer if they don’t get blocked by safety or other problems. It’s not a “cure” in the idealized genetic-modification sense, but it could become the kind of real-world treatment method that gets the problem out of our daily lives.
Finasteride/Dutasteride/RU58841/etc are not MPB regrowth methods, they are just damage control.
Minox is not an MPB regrowth method either. It’s an essentially unrelated growth method that we use to try to make up for the growth that we’ve lost to MPB. It is even farther away from addressing the core MPB problem than Finasteride/etc.
Histogen & ARI are the first methods of regrowth (not damage control) that address the MPB problem in any kind of direct way. I don’t think the patterns of effectiveness we’ve seen with treatments up to now are predictive for these new methods.
1 year after the injections, haircounts keep increasing, so I would say Histogen produces hairs that are DHT resistant. Don’t ask me why.
» » No, Histogen just uses growth factors. They don’t need to take a biopsy
» of
» » the back of your head. This is a big plus. This reduces costs
» dramatically.
» » The product is universal, can be injected to anyone, while ARI needs to
» » make a product specifically for you (they culture your cells).
»
» thanks for the info, now I know that… this is a surprise for me, how can
» a “simply” growth factor be better than your stem cells? I wonder if the
» hair will be DHT resistant and will have a natural life for years as my
» hair does in the donor
» 1 year after the injections, haircounts keep increasing, so I would say
» Histogen produces hairs that are DHT resistant. Don’t ask me why.
»
»
»
» » » No, Histogen just uses growth factors. They don’t need to take a
» biopsy
» » of
» » » the back of your head. This is a big plus. This reduces costs
» » dramatically.
» » » The product is universal, can be injected to anyone, while ARI needs
» to
» » » make a product specifically for you (they culture your cells).
» »
» » thanks for the info, now I know that… this is a surprise for me, how
» can
» » a “simply” growth factor be better than your stem cells? I wonder if
» the
» » hair will be DHT resistant and will have a natural life for years as my
» » hair does in the donor
That would be amazing if it somehow did provide DHT resistant hairs!
» » 1 year after the injections, haircounts keep increasing, so I would say
» » Histogen produces hairs that are DHT resistant. Don’t ask me why.
» »
» »
» »
» » » » No, Histogen just uses growth factors. They don’t need to take a
» » biopsy
» » » of
» » » » the back of your head. This is a big plus. This reduces costs
» » » dramatically.
» » » » The product is universal, can be injected to anyone, while ARI
» needs
» » to
» » » » make a product specifically for you (they culture your cells).
» » »
» » » thanks for the info, now I know that… this is a surprise for me, how
» » can
» » » a “simply” growth factor be better than your stem cells? I wonder if
» » the
» » » hair will be DHT resistant and will have a natural life for years as
» my
» » » hair does in the donor
»
»
» That would be amazing if it somehow did provide DHT resistant hairs!
I really don’t see how the hairs could be DHT resistant if its restimulating the same follicles.
That said … I really don’t care all that much if they were … I have no problems with this being a “Botox for hair” like treatment where you could go back every 6-12 months to get “topped off”. Of course DHT resistant would be ideal but going back every few months for a simple injection and more hair is ok by me.
I’d be happy if this can bring back 40% density of one’s original density … I mean I think that’s a pretty huge amount. Combine that with a decent HT and you should have a solution that effectively gives you solid coverage and lets you get on with your life. If it’s higher than that … obviously that would be great too.
I just want them to start the second phase of trials where the adminster a larger dose to start ASAP. We should know a lot more about this in a year or so.
» I really don’t see how the hairs could be DHT resistant if its
» restimulating the same follicles.
»
» That said … I really don’t care all that much if they were … I have no
» problems with this being a “Botox for hair” like treatment where you could
» go back every 6-12 months to get “topped off”. Of course DHT resistant
» would be ideal but going back every few months for a simple injection and
» more hair is ok by me.
»
» I’d be happy if this can bring back 40% density of one’s original density
» … I mean I think that’s a pretty huge amount. Combine that with a decent
» HT and you should have a solution that effectively gives you solid coverage
» and lets you get on with your life. If it’s higher than that … obviously
» that would be great too.
»
» I just want them to start the second phase of trials where the adminster a
» larger dose to start ASAP. We should know a lot more about this in a year
» or so.
Well the hair count and terminal hair count seem to keep going up past one year so there is a chance that these hairs will last a VERY long time.
» I really don’t see how the hairs could be DHT resistant if its
» restimulating the same follicles.
»
» That said … I really don’t care all that much if they were … I have no
» problems with this being a “Botox for hair” like treatment where you could
» go back every 6-12 months to get “topped off”. Of course DHT resistant
» would be ideal but going back every few months for a simple injection and
» more hair is ok by me.
»
» I’d be happy if this can bring back 40% density of one’s original density
» … I mean I think that’s a pretty huge amount. Combine that with a decent
» HT and you should have a solution that effectively gives you solid coverage
» and lets you get on with your life. If it’s higher than that … obviously
» that would be great too.
»
» I just want them to start the second phase of trials where the adminster a
» larger dose to start ASAP. We should know a lot more about this in a year
» or so.
personally, i have strong doubts as to DHT resistance of the rejuvenated follicles. I see can think of no reasonable explanation as to why this would occur… yet perhaps i am wrong.
furthermore the “botox” solution would be fine as long as the treatment is available for far less than USD 5.000. Paying 10.000 USD per year would not result in an affordable solution for most.
I don’t know exactly what is the mechanism, but the fact that the hairs last more than 12 months (and thus, they don’t succumb to DHT) indicate that something special is happening.
In fact, hair counts keep increasing at 12 months, which is really interesting.
I think Histogen is making fundamental changes in the skin that bears the follicles and this is why they are not the same follicles as before, and this is why they are DHT resistant.
So, even if the results are not espectacular in terms of gained haircounts, there is a chance that Histogen is modifying the existing hairs and making them DHT resistant.
Lets supposse that the effects last 2 years. Being injected like Botox each 2 years seems plausible, as long as the price is economical. I think HSC can be manufactured in big quantities and low cost, so I think selling it at a low price is feasible.
On contrast, ARI’s product is inherently expensive because is a TAILOR MADE product, and requires a biopsy, and many injections. It cannot be manufactured in masse.
» » I really don’t see how the hairs could be DHT resistant if its
» » restimulating the same follicles.
» »
» » That said … I really don’t care all that much if they were … I have
» no
» » problems with this being a “Botox for hair” like treatment where you
» could
» » go back every 6-12 months to get “topped off”. Of course DHT resistant
» » would be ideal but going back every few months for a simple injection
» and
» » more hair is ok by me.
» »
» » I’d be happy if this can bring back 40% density of one’s original
» density
» » … I mean I think that’s a pretty huge amount. Combine that with a
» decent
» » HT and you should have a solution that effectively gives you solid
» coverage
» » and lets you get on with your life. If it’s higher than that …
» obviously
» » that would be great too.
» »
» » I just want them to start the second phase of trials where the adminster
» a
» » larger dose to start ASAP. We should know a lot more about this in a
» year
» » or so.
»
» personally, i have strong doubts as to DHT resistance of the rejuvenated
» follicles. I see can think of no reasonable explanation as to why this
» would occur… yet perhaps i am wrong.
»
» furthermore the “botox” solution would be fine as long as the treatment is
» available for far less than USD 5.000. Paying 10.000 USD per year would not
» result in an affordable solution for most.
» I don’t know exactly what is the mechanism, but the fact that the hairs
» last more than 12 months (and thus, they don’t succumb to DHT) indicate
» that something special is happening.
» In fact, hair counts keep increasing at 12 months, which is really
» interesting.
»
» I think Histogen is making fundamental changes in the skin that bears the
» follicles and this is why they are not the same follicles as before, and
» this is why they are DHT resistant.
»
» So, even if the results are not espectacular in terms of gained
» haircounts, there is a chance that Histogen is modifying the existing
» hairs and making them DHT resistant.
»
» Lets supposse that the effects last 2 years. Being injected like Botox
» each 2 years seems plausible, as long as the price is economical. I think
» HSC can be manufactured in big quantities and low cost, so I think selling
» it at a low price is feasible.
» On contrast, ARI’s product is inherently expensive because is a TAILOR
» MADE product, and requires a biopsy, and many injections. It cannot be
» manufactured in masse.
»
»
»
» » » I really don’t see how the hairs could be DHT resistant if its
» » » restimulating the same follicles.
» » »
» » » That said … I really don’t care all that much if they were … I
» have
» » no
» » » problems with this being a “Botox for hair” like treatment where you
» » could
» » » go back every 6-12 months to get “topped off”. Of course DHT
» resistant
» » » would be ideal but going back every few months for a simple injection
» » and
» » » more hair is ok by me.
» » »
» » » I’d be happy if this can bring back 40% density of one’s original
» » density
» » » … I mean I think that’s a pretty huge amount. Combine that with a
» » decent
» » » HT and you should have a solution that effectively gives you solid
» » coverage
» » » and lets you get on with your life. If it’s higher than that …
» » obviously
» » » that would be great too.
» » »
» » » I just want them to start the second phase of trials where the
» adminster
» » a
» » » larger dose to start ASAP. We should know a lot more about this in a
» » year
» » » or so.
» »
» » personally, i have strong doubts as to DHT resistance of the
» rejuvenated
» » follicles. I see can think of no reasonable explanation as to why this
» » would occur… yet perhaps i am wrong.
» »
» » furthermore the “botox” solution would be fine as long as the treatment
» is
» » available for far less than USD 5.000. Paying 10.000 USD per year would
» not
» » result in an affordable solution for most.
if you look at subject S1006 you will see the hair count has DECREASED from the 12 week count to the 1 year.
Possible effects of DHT