ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009

Stem cell; cell based hair therapy
61

» if you read the mens health article that was posted in this forum, what
» there are doing did NOT work on a mouse. So I dont think they got there
» pre trails right.

What the article said was that injecting HUMAN cells into MICE didn’t work. But in clinical trials they’re injecting HUMAN cells into HUMANS.

»
» Thats what makes follica technique more impressive. Human hair on human
» skin. Yes it was on a mouse, but they understand that the immune system
» has to be suppressed. I don’t think these other companies understand this.

I’m sure the Aderans researchers are competent enough to know how to do research on mice. It’s pretty standard.

62

» » Histogen presented their 5 month data at the conference and the data so
» » far looks very good, but Rassman chose to ignore that point in his post
» » (probably because technically what follica and histogen are doing is
» not
» » hair clonning, but on the other hand what ICX and adernas are doing is
» not
» » cloning but multiplication which seems to be exceptably interchangable
» » phrases in hair restoration).
»
» No way. Histogen didn’t present the 5-month data, but rather the old 12
» week data. I asked Dr. Naughton via email, about this point, but she didn’t
» answer to this question in her reply (she said she would answer later, with
» an official answer, but I am still waiting).
»
»
» »» We can take it from this info that Rassmans insight comes from Farjo
» and
» » Gho only, who we all know failed along time ago.
»
» I think Washenik was also at the conference, I don’t know if he
» intervened. Anyone knows?

I just checked and your right it is just the 12 week data, thats a bit strange.
I assumed they would be showing the 24 week data seeing as the trial concluded a while ago and thats what we were led to believe they were presenting.
Maybe they will show aditional info from the end of the trial in the next few weeks? It finished weeks ago.
How long have you been waiting for a reply?
The 12 week data is still good news though in my opinion and they said that there was no safety issues and good efficiacy at the end of the 24 weeks so thats a good sign.

Washenik was there according to the programme as the ‘program chair’(I don’t think he was there on the same days as Rassmans discusions though), he also introduced the discusion of current non surgical and medical treatments, which was a review of current treatments such as minoxidil and treatments being studied such as dutasteride.
I doubt he would have given any information on Aderans trials seeing as they only recently started phase II and he was more like a host.

If you look here, page 11, http://www.ishrs.org/PDF/Prelim02_2009ASM_FULL.pdf

The discusion on HM was carried out by;
William Rassman as moderator,
Bassam Farjo,
Takashi Hirayama,
Demkerng Pathaomvanich
and
Coen Gho

We all know about Gho’s failure with HM and Farjo was overseeing ICX trial , however I have no Idea who the others are.

Bassam Farjo also participated in the discussion on growth factors amoung others and Nilofer Farjo also did and extra program on Cell therapy in hair restoration.

I think in Rassmans original post he was reffering to the companies he is aware of trials not going so well and HM being 10 years away at least, not that it’s an unlikely guess.

63

» Hair Multiplication or Hair cloning are already being overtaken rapidly by
» what Follica are doing. I’m not worried one bit by what Rassman or any
» other clown involved in hair transplants has to say, they’re sounding more
» and more desperate to cling on to their relevance.

People ask him about Follica and Histogen on his blog from time to time, I don’t think he’s convinced that they have anything.

This is what one of his blog entries about Follica says-
“What does this all mean for the future of hair cloning / multiplication? Well, that remains to be seen. This is exciting stuff and I hope the additional funds will bring this technology to the next level. As for when/if it’ll make it to market — well, I couldn’t say. Follica just came on the scene in late 2006 and I’d expect many years to come before anything of substance came out, if at all. Not to be a pessimist, but we’ve seen a number of failed attempts at these types of methods over the years. Lots of questions remain, and this is still the very, very early stages”

He seems to have a pretty realistic view I think, unlike the people who seem to think they will be on the market in 2 years.
However I don’t see how him being a transplant doc gives him any authiority on the matter, there are people on this board with far more knowledge on what Follica are doing than him.
He doesn’t have access to any more info than we do, he said it himself on his blog regarding Aderans.
At the end of the day his main goals are to sell propecia and HT’s.

I read that Aderans phase II that just started is due to end in 2010, can anyonw confirm this? any more info?

64

Let’s not forget that Rassman is a hair transplant doctor, he has no vested interest to talk Histogen and Follica up.

oh yea, Aderans is officially in phase II now

65

I read that Aderans phase II that just started is due to end in 2010, can
anyonw confirm this? any more info?

i have now idea when they finish phase 2 but if i think about this a little that they will finish phase 2 at the end of 2010, then it takes so many years when hm is ready for market.

i see 2 scenarios:

scenario 1 - if they finish phase 2 at the of 2010 then this phase lasts about 2 years (do you know how long was phase 1?). then they collect and document all data which may take at least 1 year or possibly even longer. if everything goes what they hoped then they start preparations to phase 3 (phase 3 should be FDA proval phase like i understood?). it might take again 1 year and finally if they will launch phase 3 then this phase will took again about 2 years. if everything ok with phase 3 then there will go maybe 1-2 years more when they have got fda aproval. so, lets take a look back to my first scenario now and lets count the years when hm might be ready for us. i don’t wanna be pessimist but unfortunately i see there are minimum 7-8 years.

scenario 2 - they launched phase 2 and this lasts at the end of 2010 (about 2 years). then they collect and document data which take 1 year. if their results were crap then we are back to phase 2 again and we even don’t know when they start this base one more time (they start to look what they did wrong and then they start to create new ideas which leads to phase 2 again - so it’s very very long run when they start phase 2 again). this is the worst scenario and hopefully it’s not gonna happen but if it does then hm by aderans wont be on the market before 15-20 years or even possibly longer i think. And if they give up then we don’t have nothing. we all know that intercytex failed and it might happen to aderans as well. i belive that intercytex guys wanted to bring this product on the market too (look how much (investors)money they put in it and finally they haven’t got nothing - all these lost years and lost money) but unfortunately they couldnt.

66

» » if you read the mens health article that was posted in this forum, what
» » there are doing did NOT work on a mouse. So I dont think they got
» there
» » pre trails right.
»
» What the article said was that injecting HUMAN cells into MICE didn’t
» work. But in clinical trials they’re injecting HUMAN cells into HUMANS.
»

Right, there pre clinical trials did not go the way they were hoping like you stated. ARI is taking a two cell approach as compared to the one cell approach ICX tried. They are basically throwing darts at a dartboard and hoping something sticks. The only thing they have proven so far is what they are doing is safe.

» »
» » Thats what makes follica technique more impressive. Human hair on
» human
» » skin. Yes it was on a mouse, but they understand that the immune
» system
» » has to be suppressed. I don’t think these other companies understand
» this.
»
» I’m sure the Aderans researchers are competent enough to know how to do
» research on mice. It’s pretty standard.

67

» I just checked and your right it is just the 12 week data, thats a bit
» strange.
» I assumed they would be showing the 24 week data seeing as the trial
» concluded a while ago and thats what we were led to believe they were
» presenting.
» Maybe they will show aditional info from the end of the trial in the next
» few weeks? It finished weeks ago.
» How long have you been waiting for a reply?
» The 12 week data is still good news though in my opinion and they said
» that there was no safety issues and good efficiacy at the end of the 24
» weeks so thats a good sign.

I emailed her on Monday night, and she replied to me in 3 hours.
look here:
http://www.hairsite.com/hair-loss/forum_entry-id-55819-page-0-category-1-order-last_answer.html
but now I am waiting for the good answer.

»
» Washenik was there according to the programme as the ‘program chair’(I
» don’t think he was there on the same days as Rassmans discusions though),
» he also introduced the discusion of current non surgical and medical
» treatments, which was a review of current treatments such as minoxidil and
» treatments being studied such as dutasteride.
» I doubt he would have given any information on Aderans trials seeing as
» they only recently started phase II and he was more like a host.
»
» If you look here, page 11,
» http://www.ishrs.org/PDF/Prelim02_2009ASM_FULL.pdf
»
» The discusion on HM was carried out by;
» William Rassman as moderator,
» Bassam Farjo,
» Takashi Hirayama,
» Demkerng Pathaomvanich
» and
» Coen Gho
»
» We all know about Gho’s failure with HM and Farjo was overseeing ICX trial
» , however I have no Idea who the others are.
»
» Bassam Farjo also participated in the discussion on growth factors amoung
» others and Nilofer Farjo also did and extra program on Cell therapy in hair
» restoration.
»
» I think in Rassmans original post he was reffering to the companies he is
» aware of trials not going so well and HM being 10 years away at
» least, not that it’s an unlikely guess.

Ok, I don’t know if Rassman talked to Washenik about ARI’s progress, but when Rassman is making that grim prediction, I would assume he is well informed about ARI’s progress and he included ARI in his judgement.

68

» we all know that intercytex failed and it might happen to aderans as well. i
» belive that intercytex guys wanted to bring this product on the market too
» (look how much (investors)money they put in it and finally they haven’t got
» nothing - all these lost years and lost money) but unfortunately they
» couldnt.

krapok:
you must note that ICX allocated a ridiculous amount of money to TRC. Almost all their money went to ICX PRO. PRO trials were large trials. TRC had very very small cohorts, just about a dozen trialists in phase II.

ARI is enrolling, AFAIK, about 100 trialists for phase II. It is a multicenter trial. They are spending a decent amount of money.

TRC’s failure doesn’t mean that ARI is going to fail. ARI has much more chances to succeed than TRC, IMO.

Of course, you can say: If ICX-PRO failed, with lots of resources, ARI can also fail. This would be a good reasoning.

69

» » we all know that intercytex failed and it might happen to aderans as
» well. i
» » belive that intercytex guys wanted to bring this product on the market
» too
» » (look how much (investors)money they put in it and finally they haven’t
» got
» » nothing - all these lost years and lost money) but unfortunately they
» » couldnt.
»
» krapok:
» you must note that ICX allocated a ridiculous amount of money to TRC.
» Almost all their money went to ICX PRO. PRO trials were large trials. TRC
» had very very small cohorts, just about a dozen trialists in phase II.
»
» ARI is enrolling, AFAIK, about 100 trialists for phase II. It is a
» multicenter trial. They are spending a decent amount of money.
»
» TRC’s failure doesn’t mean that ARI is going to fail. ARI has much more
» chances to succeed than TRC, IMO.
»

» Of course, you can say: If ICX-PRO failed, with lots of resources, ARI can
» also fail. This would be a good reasoning.

I live in one of the trial areas. They just started advertising in the free daily paper again. I hadn’t seen an ad in about three months, now they’re in there every day again.
ARI is at least 10 years off. Thats a guess, obviously, but it doesnt seem to have any chance of being on the market any time sooner. I would say 10 years is actually pretty optimistic.
In my view, if we’re very lucky, Histogen or Follica will have something in 7 years or so. Is that hair permanent? Probably not. Is it going to look ok? Who knows.
A full, permanent head of hair ain’t coming any time soon.

70

» Right, there pre clinical trials did not go the way they were hoping like
» you stated. ARI is taking a two cell approach as compared to the one cell
» approach ICX tried. They are basically throwing darts at a dartboard and
» hoping something sticks. The only thing they have proven so far is what
» they are doing is safe.
»

If the pre-clinical trials produced poor results, and phase I produced poor results, would Aderans proceed with a multi-center 100+ tiralists phase II? You be the judge.

71

I read this on another message board and have already posted it in another thread on here, but i’ll post it again because yet again people are pulling timelines out of their arses. It was written by someone who was sick of people being misinformed about trials.

I was doing some research about clinical trials the other day to dispel a lot of the rumors I had been hearing. As it turns out “research studies”, “clinical research”, and “human proof of concept studies” can all be used interchangeably for Phase 1 and Phase 2 clinical trials. Once these are done, Phase 3 takes about another year in most cases. Most of us, because we are so concerned, would be perfect candidates for Phase 3 and can have access to these treatments before they ever hit the market.

I don’t know how this is misconstrued as optimism. I am well aware, and have said repeatedly, that companies in Phase 2 often fail. But companies in Phase 2 also never take 10 years to market. This is just factual, it’s not “hopeful.”

72

Maybe you are right. I cannot prove you wrong about your prediction. I am an oldtimer here, and I know how easily optimistic predictions fail.
I think if everything goes well, ARI’s product could be launched in 3-4 years. This is a huge IF, of course.

Regarding ARI’s advertisements, are you referring to the recruitment ads for phase II, right?
how do you interpret the 3-months interval without advertisements?
is it possible that they recruited enough volunteers 3 months ago, then stopped recruitment, and now, after the first batch has been injected, they are seeking for more volunteers? this could confirm that they indeed are going to inject a lot of people.

Do you say that there are ads in the free daily paper? Only in the free paper? Is this just one paper? It would be interesting to see the ad. Can you scan it or barely describe it?

» » » we all know that intercytex failed and it might happen to aderans as
» » well. i
» » » belive that intercytex guys wanted to bring this product on the
» market
» » too
» » » (look how much (investors)money they put in it and finally they
» haven’t
» » got
» » » nothing - all these lost years and lost money) but unfortunately they
» » » couldnt.
» »
» » krapok:
» » you must note that ICX allocated a ridiculous amount of money to TRC.
» » Almost all their money went to ICX PRO. PRO trials were large trials.
» TRC
» » had very very small cohorts, just about a dozen trialists in phase II.
» »
» » ARI is enrolling, AFAIK, about 100 trialists for phase II. It is a
» » multicenter trial. They are spending a decent amount of money.
» »
» » TRC’s failure doesn’t mean that ARI is going to fail. ARI has much more
» » chances to succeed than TRC, IMO.
» »
»
»
» » Of course, you can say: If ICX-PRO failed, with lots of resources, ARI
» can
» » also fail. This would be a good reasoning.
»
» I live in one of the trial areas. They just started advertising in the
» free daily paper again. I hadn’t seen an ad in about three months, now
» they’re in there every day again.
» ARI is at least 10 years off. Thats a guess, obviously, but it doesnt seem
» to have any chance of being on the market any time sooner. I would say 10
» years is actually pretty optimistic.
» In my view, if we’re very lucky, Histogen or Follica will have something
» in 7 years or so. Is that hair permanent? Probably not. Is it going to look
» ok? Who knows.
» A full, permanent head of hair ain’t coming any time soon.

73

I think if the product works well, there will be plenty of money to push it ahead, and if the company is competent, the 3 trials could be done in 5 years.

Note that most tentative products don’t work well (at least at the beginning). Then the FDA will start nitpicking it, and investors will be coward.

» I read this on another message board and have already posted it in another
» thread on here, but i’ll post it again because yet again people are pulling
» timelines out of their arses. It was written by someone who was sick of
» people being misinformed about trials.
»
» I was doing some research about clinical trials the other day
» to dispel a lot of the rumors I had been hearing. As it turns out “research
» studies”, “clinical research”, and “human proof of concept studies” can all
» be used interchangeably for Phase 1 and Phase 2 clinical trials. Once these
» are done, Phase 3 takes about another year in most cases. Most of us,
» because we are so concerned, would be perfect candidates for Phase 3 and
» can have access to these treatments before they ever hit the market.
»
» I don’t know how this is misconstrued as optimism. I am well aware, and
» have said repeatedly, that companies in Phase 2 often fail. But companies
» in Phase 2 also never take 10 years to market. This is just factual, it’s
» not “hopeful.”

74

» Maybe you are right. I cannot prove you wrong about your prediction. I am
» an oldtimer here, and I know how easily optimistic predictions fail.
» I think if everything goes well, ARI’s product could be launched in 3-4
» years. This is a huge IF, of course.
»
» Regarding ARI’s advertisements, are you referring to the recruitment ads
» for phase II, right?
» how do you interpret the 3-months interval without advertisements?
» is it possible that they recruited enough volunteers 3 months ago, then
» stopped recruitment, and now, after the first batch has been injected, they
» are seeking for more volunteers? this could confirm that they indeed are
» going to inject a lot of people.
»
» Do you say that there are ads in the free daily paper? Only in the free
» paper? Is this just one paper? It would be interesting to see the ad. Can
» you scan it or barely describe it?
»
» » » » we all know that intercytex failed and it might happen to aderans
» as
» » » well. i
» » » » belive that intercytex guys wanted to bring this product on the
» » market
» » » too
» » » » (look how much (investors)money they put in it and finally they
» » haven’t
» » » got
» » » » nothing - all these lost years and lost money) but unfortunately
» they
» » » » couldnt.
» » »
» » » krapok:
» » » you must note that ICX allocated a ridiculous amount of money to TRC.
» » » Almost all their money went to ICX PRO. PRO trials were large trials.
» » TRC
» » » had very very small cohorts, just about a dozen trialists in phase
» II.
» » »
» » » ARI is enrolling, AFAIK, about 100 trialists for phase II. It is a
» » » multicenter trial. They are spending a decent amount of money.
» » »
» » » TRC’s failure doesn’t mean that ARI is going to fail. ARI has much
» more
» » » chances to succeed than TRC, IMO.
» » »
» »
» »
» » » Of course, you can say: If ICX-PRO failed, with lots of resources,
» ARI
» » can
» » » also fail. This would be a good reasoning.
» »
» » I live in one of the trial areas. They just started advertising in the
» » free daily paper again. I hadn’t seen an ad in about three months, now
» » they’re in there every day again.
» » ARI is at least 10 years off. Thats a guess, obviously, but it doesnt
» seem
» » to have any chance of being on the market any time sooner. I would say
» 10
» » years is actually pretty optimistic.
» » In my view, if we’re very lucky, Histogen or Follica will have
» something
» » in 7 years or so. Is that hair permanent? Probably not. Is it going to
» look
» » ok? Who knows.
» » A full, permanent head of hair ain’t coming any time soon.

The ads are in the medical research section of the Metro. The Metro is a free daily paper available in many of the world’s large cities.
If I remember right, the metro ad is basically the same as their “clinical updates” page.

75

» The ads are in the medical research section of the Metro. The Metro is a
» free daily paper available in many of the world’s large cities.
» If I remember right, the metro ad is basically the same as their “clinical
» updates” page.

ok, thanks. I guess that ad is enough to reach a lot of people.

76

These ARI “Hair Loss Study” ads are also appearing almost daily in Washington, DC’s “Express” free daily newspaper. It says they are looking for male and female test subjects between ages 18 and 65, for a “cell based hair restoration study in Washington, DC”.

77

great! thanks roger_that.
As we have little information supplied by ARI, these pieces of information are very valuable to help us evaluate how important/big are these trials.

if anyone else have seen ARI ads on any other paper, please post here about it.

» These ARI “Hair Loss Study” ads are also appearing almost daily in
» Washington, DC’s “Express” free daily newspaper. It says they are looking
» for male and female test subjects between ages 18 and 65, for a “cell based
» hair restoration study in Washington, DC”.

78

Information again from another place (copied text here)

The Doctor at the Aderans Interview Said Cloning Would Be Available in 5 Years
August 4 2009, 2:34 pm PT | Posted in: Drugs + Hair Cloning

Dear Dr. Rassman,

I am a 29 year old male. I became aware of thinning in my crown area in April of ‘09, and got on Propecia at the beginning of May. I volunteered for the Aderan’s phase II hair/cell replication study, but was told I had too much hair to be a subject. The Dr. at the clinic where I was interviewed said the cloning procedure would be available in about 5 years.You state that you see the cloning procedure as a decade off, so from the information you’ve gotten at this recent convention, is it reasonable to imagine that in my late thirties, around 2019 or so, that I can get hair restoration through a cloning procedure? And in the next few years, do you see a better drug, like an FDA approved version of Dutasteride coming to market?

Thank you for you time

The folks at Aderans predicted the cloning solution would be available in 5 years… and that was 5 years ago. So by that timeline, it should be here now… yet here we are, wondering where it is. I probed that question to those who are knowledgeable and found that no one really expects a cloning solution in 5 years. Perhaps ten years… and maybe more.

Dutasteride is already FDA approved to treat the prostate, but I’d like to think it’ll be available for treating hair loss at some point down the line, once any other studies are concluded and safety can be assured. It’s not up to me, and I’ve got my reservations about the medication already. There are no other new hair loss drugs like dutasteride that I know of coming in the next 5 year horizon. It takes years to clear it through the FDA so we will have plenty of notice when the process starts for a new medication.

79

Thanks Krapok, that is another useful post.
I see important information:
-ARI is seeking for very bald volunteers, not just thinning. This is a good sign. This was mentioned in the paper ads, but now it is confirmed by this volunteer applicant.
-ARI thinks they will be ready in 5 years.
-Rassman doesn’t believe this 5-year prediction, and according to his contacts, noone believes it either.

We will see… so far, Rassman’s negativity has been the winner.
But I don’t think that Rassman is so well informed as he says. A few months ago, he posted some positive comments about HM, specifically about ICX. And now we see that he was not right.

I was very hard to Dr, Washenik a few years ago, because he was behaving a bit weird, advertising HTs on TV for Bosley, and using HM as bait. And in an interview about HM, he spend most of the time praising Propecia and Minoxidil.

But now, I think he is doing well. He is not talking about it anymore in the media, but materializing real steps forward.

I think is possible that ARI has a product in less than 5 years.

» Information again from another place (copied text here)
»
» The Doctor at the Aderans Interview Said Cloning Would Be Available in 5
» Years
» August 4 2009, 2:34 pm PT | Posted in: Drugs + Hair Cloning
»
» Dear Dr. Rassman,
»
» I am a 29 year old male. I became aware of thinning in my crown area in
» April of ‘09, and got on Propecia at the beginning of May. I volunteered
» for the Aderan’s phase II hair/cell replication study, but was told I had
» too much hair to be a subject. The Dr. at the clinic where I was
» interviewed said the cloning procedure would be available in about 5
» years.You state that you see the cloning procedure as a decade off, so from
» the information you’ve gotten at this recent convention, is it reasonable
» to imagine that in my late thirties, around 2019 or so, that I can get hair
» restoration through a cloning procedure? And in the next few years, do you
» see a better drug, like an FDA approved version of Dutasteride coming to
» market?
»
» Thank you for you time
»
» The folks at Aderans predicted the cloning solution would be available in
» 5 years… and that was 5 years ago. So by that timeline, it should be here
» now… yet here we are, wondering where it is. I probed that question to
» those who are knowledgeable and found that no one really expects a cloning
» solution in 5 years. Perhaps ten years… and maybe more.
»
» Dutasteride is already FDA approved to treat the prostate, but I’d like to
» think it’ll be available for treating hair loss at some point down the
» line, once any other studies are concluded and safety can be assured. It’s
» not up to me, and I’ve got my reservations about the medication already.
» There are no other new hair loss drugs like dutasteride that I know of
» coming in the next 5 year horizon. It takes years to clear it through the
» FDA so we will have plenty of notice when the process starts for a new
» medication.

80

» Ok, nothing about the specifics of the trial:
» -Number of trialists.
» -Use of scaffolds or not.
» -Duration of the trial.
»
» We will see…
»
» They are being quite silent about it. this means that they are not using
» these trials for propaganda purposes, which is a good sign.

-Number of trialists.

There should be a lot of number of trialists because people can participate in 6 different countries. At the moment i’m interested how many people they already have found. I hope their trials going well at the moment and i hope they have anough people to conclude their studies.

-Duration of the trial.

This is interesting question. Made a little research and i found that Phase 2 expected to be completed by the end of 2009. Information comes from this site http://www.surviving-hairloss.com/Cloning.html (look below, i copied ARI’s information there too)

I don’t know from where they got this information (directly from ARI?) but i hope its true. If they gonna complete their studies by the end of 2009 (after 4 months) and if they started their trial by the end of Arpil 2009 then it means that they are already in halfway in their Phase 2. Someone should give them a call and ask how they are doing and what kind of progress they have seen during the first 4 months.

I’m interested about this that how many different ways they try to inject dp cells into human skin and how many different ways multiplied cells they are using. I hope they are trying inject a lot of ways multiplied cells in human skin. I read that they use DP cells which are combined with another type of cell known as Keratinocytes but i hope at the same time that they have more backups what they are using in their Phase 2 studies. More backups means more success because at the moment no one knows exactly what elicit hair growth in human skin.

If ARI’s studies are successful and they complete their Phase 2 by the end of this year then how long it takes exactly to bring this cure to market? I know that in US are FDA regulations and they must have Phase 3 too but how fast they can bring this cure to market in Europe where isn’t FDA regulations? Is it possible to bring this cure to market in Europe already after their succesful phase 2 or i’m wrong?

Reading previous post we see that ARI told they have HM during 5 years. Does it mean that they have HM cure during 5 years in all over the world or it might be available already before (before in Europe without FDA)? I really want to believe that they can bring this cure to market soon but at the same time i afraid again that it’s not that easy and we don’t see nothing during 5 years. I remember ARI has promised before that HM will be in market 2007, then by the end of 2010 and now when they deleted 2010 from their website and told to one guy that during 5 years then we have seen a lot of delays and those are bad news. Years are flying and no one dosn’t get younger. We don’t need only promises, we need something what really works and we need it fast. I don’t wanna wait another 5 years (by the end of 2014) to get new information that we need more 5 years :S

http://www.surviving-hairloss.com/Cloning.html

Another interesting entity that we should pay attention to is the Aderans Research Institute (ARI) based in Atlanta and Philadelphia. ARI is actually a research arm of the largest hair transplant network in the USA, more famously known as BOSLEY Group which has hair transplant franchises all over the country. (Bosley’s parent company itself is the large Japanese firm known as ADERANS Ltd, the largest wig manufacturer in the world.)

ARI is dedicated in developing and researching methods to perfect the hair cloning process. The research team is lead by Dr. Washenik and Dr. Stenn, both famous in the field of hair biology and restoration.

Aderans Research Institute is currently performing phase II trials of their hair cloning technique which slightly differs from the rest. Noting the process as ‘follicular neogenesis’ the technique involves more than just growing the dermal papilla cells alone but instead combining them in culture dishes with another type of cell known as Keratinocytes.

One of the major obstacles in hair cloning is that dermal papilla cells usually lose their ability to form hair follicles once they are cultured outside of the body. The suspected reason is because of the absence of other cells to ‘remind them’ of their purpose. Therefore, the team’s main approach is by hoping that if these cells are cultured together, it will help the dermal papilla cells to remember its ability and hopefully will be able to form hair follicles once inserted back into the scalp.

Currently phase II trials are taking place and it’s expected to be completed by the end of 2009.