Acell vs Dr. Jones. Who is to blame? In depth analysis

I have compiled all the posts regarding this issue, and here is my analysis:

According to Jones,
1. Jones followed Acell’s instructions exactly. Jones insists on this several times.
2. Acell didn’t provide an alternative method for a second try, and that is why the project was abandoned.

According to Costanza (who contacted Acell):
Costanza posted 2 posts, which contradict each other:
-1st. Jones deviated from Acell instructions. Acell wanted the wound bandaged and moist, and powder reaplied. Jones simply let the scar to form alone.
-2nd. Jones followed Acell instructions but patient didn’t: Acell wanted wound not bandaged, just keeping moist by gauzes, (no mention of reapplying powder).
The patient didn’t apply gauzes, the wound dried, and experiment failed.

As you see, Costanza contradicts himself on who is to blame, and on the set of instructions provided by Acell.

Regarding the instructions provided by Acell:
In the first post, Costanza says that Acell wanted the wound bandaged and moist, and powder reaplied several times.
But in the second post, Costanza says that Acell just wanted the wound moist by applying wet gauzes, and doesn’t mention if the powder has to be reapplied.
(no mention of how the gauzes are supposed to be applied overnight).

Regarding who is to blame:
In the first post, Costanza says that Dr. Jones deviated from Acells instructions.
In the second post, Costanza says that Dr. Jones followed Acell’s instructions, but the patient didn’t.

Regarding repetition of experiment:
Jones expressed repeatedly his willingness to repeat the experiment if it failed first time. But he finally said that Acell didn’t provide an alternative protocol, so he wouldn’t try again.

Spanish Dude’s veredict: Unless further evidence is presented, I vouch for Jones. Sorry but my impression is that Acell reps, Manning and Rodney Bosley did a very poor job.

p.d: next on a separate post, I post all the messages by Jones and Costanza

Compilation of messages:
Costanza posted on Hairsite, Dr. Jones posted on his blog (except the final comment, that he posted on Hairsite). Only the relevant portions are posted here.
Jones’ blog: http://www.drrobertjones.com/acell.html

Dr. Robert Jones Tuesday, 2008-Nov-18-two weeks post-op
There have been many questions sent to me on the methods used and the expected outcome of this patient.The protocol that I used followed the suggestions put forward by a representative of the Acell company. I followed their suggestions as closely as I could and have been in phone contact with them several times discussing this patients progress.
If this is not successful, I plan to try another strategy along with the Acell company to try to make this work. I would ask that everyone be patient, since this is the first patient where Acell has been used in this application.

Dr. Robert Jones Wednesday, January 7, 2009–10 weeks post op
The protocol for this procedure was provided by the company that supplies the Acell product.

Costanza 8-Jan-2009:
Dr. Jones deviated from Acell’s instructions to try worst case scenario.
Spoke with Manning, the Acell rep, and learned that Dr. Jones was trying to see if the wound would heal under the worst case scenario conditions. Manning admitted that the wound should have been kept moist and under a bandaged for several weeks and that acell should have been reapplied several times.
Rodney Bosley, the VP from Acell who was instructing Jones wanted him to keep the wound bandaged and moist but apparently Jones hoped that the scab would be sufficient to keep the wound moist.
In any event, Manning said that they hoped to have photos from other physician on their site soon. This most likely means Spring but hopefully sooner rather than later.

Dr. Robert Jones Wednesday, January 28, 2009–12 weeks post-op
The acell was used following exact directions from the company.
If I see no growth over the next month, I will consult with representative from Acell again and consider trying another patient.

Costanza 29-Jan-2009:
It turns out that Dr. Jones told the patient to keep the wound moist by applying a gauze without the need to keep it bandaged. This was the instructions given to Jones by Acell via email. However, it does not look like the patient did this as the hairs around the wound would have been moist and pasty if he removed the gauze just for the photos.

Dr. Robert Jones Tuesday, April 14, 2009–5.5 months post-op
As I said before, I follow the instructions provided by the company exactly. I also spoke with the rep from Acell during the treatment to discuss treatment protocol and progress.

Dr. Robert Jones 15, April, 2009 --post at Hairsite
At this point, I am done with Acell. I didn’t see any results from the first patient and the company has not provided me with an alternative protocol so until I feel that I have a method that I think is viable I will not do another Acell procedure,

» I have compiled all the posts regarding this issue, and here is my
» analysis:
»
»
» According to Jones,
» 1. Jones followed Acell’s instructions exactly. Jones insists on
» this several times.
» 2. Acell didn’t provide an alternative method for a second try, and
» that is why the project was abandoned.
»
» According to Costanza (who contacted Acell):
» Costanza posted 2 posts, which contradict each other:
» -1st. Jones deviated from Acell instructions. Acell wanted the
» wound bandaged and moist, and powder reaplied. Jones simply let the scar to
» form alone.
» -2nd. Jones followed Acell instructions but patient didn’t: Acell
» wanted wound not bandaged, just keeping moist by gauzes, (no mention of
» reapplying powder).
» The patient didn’t apply gauzes, the wound dried, and experiment failed.
»
» As you see, Costanza contradicts himself on who is to blame, and on the
» set of instructions provided by Acell.
»
» Regarding the instructions provided by Acell:
» In the first post, Costanza says that Acell wanted the wound bandaged and
» moist, and powder reaplied several times.
» But in the second post, Costanza says that Acell just wanted the wound
» moist by applying wet gauzes, and doesn’t mention if the powder has to be
» reapplied.
» (no mention of how the gauzes are supposed to be applied overnight).
»
» Regarding who is to blame:
» In the first post, Costanza says that Dr. Jones deviated from Acells
» instructions.
» In the second post, Costanza says that Dr. Jones followed Acell’s
» instructions, but the patient didn’t.
»
»
» Regarding repetition of experiment:
» Jones expressed repeatedly his willingness to repeat the experiment if it
» failed first time. But he finally said that Acell didn’t provide an
» alternative protocol, so he wouldn’t try again.
»
»
» Spanish Dude’s veredict: Unless further evidence is presented, I
» vouch for Jones. Sorry but my impression is that Acell reps, Manning and
» Rodney Bosley did a very poor job.
»
»
» p.d: next on a separate post, I post all the messages by Jones and
» Costanza

In the Hitzig interview posted here the other day, Hitzig spoke of an HT doc, whose name Hitzig couldn’t remember, but whom Hitzig believed was in Canada, and how this doctor used ACell on a strip scar and the results were equivocal.

Hitzig went on to say that doctor had not followed the proper use of ACell, saying among other things that the wound should be kept moist and yucky until it heals, which would mean no scabbing. And otherr things I forgot.

Whose to blame? I dunno.

Could be nobody. Could be ACell didn’t know the best way to use the stuff on scalp skin until more recently.

Probably Hitzig only knows Acell’s version of the story.

I think Acell reps, Manning and Rodney Bosley did a very poor job. Somehow, they didn’t instruct Jones correctly enough. But worse, they blamed Jones for the result, and I think Dr. Jones got upset. Probably because of this, Jones lost his interest in repeating the experiment.
Still, Dr. Jones says that Acell didn’t provide him with an alternative protocol. If this is true, then Acell would have double blame.

I don’t know, Jones was very transparent and honest with this experiment and the PRP experiment. And Acell lied about the finger story. So my vouch goes for Jones.

By the way, Hitzig and Kobren talked about the Acell finger story, but they didn’t mention that this was a total manipulation.

Also, Willy has not been mentioned by Cooley or Hitzig. I think this is not fair.

» » I have compiled all the posts regarding this issue, and here is my
» » analysis:
» »
» »
» » According to Jones,
» » 1. Jones followed Acell’s instructions exactly. Jones insists on
» » this several times.
» » 2. Acell didn’t provide an alternative method for a second try,
» and
» » that is why the project was abandoned.
» »
» » According to Costanza (who contacted Acell):
» » Costanza posted 2 posts, which contradict each other:
» » -1st. Jones deviated from Acell instructions. Acell wanted the
» » wound bandaged and moist, and powder reaplied. Jones simply let the scar
» to
» » form alone.
» » -2nd. Jones followed Acell instructions but patient didn’t:
» Acell
» » wanted wound not bandaged, just keeping moist by gauzes, (no mention of
» » reapplying powder).
» » The patient didn’t apply gauzes, the wound dried, and experiment
» failed.
» »
» » As you see, Costanza contradicts himself on who is to blame, and on the
» » set of instructions provided by Acell.
» »
» » Regarding the instructions provided by Acell:
» » In the first post, Costanza says that Acell wanted the wound bandaged
» and
» » moist, and powder reaplied several times.
» » But in the second post, Costanza says that Acell just wanted the wound
» » moist by applying wet gauzes, and doesn’t mention if the powder has to
» be
» » reapplied.
» » (no mention of how the gauzes are supposed to be applied overnight).
» »
» » Regarding who is to blame:
» » In the first post, Costanza says that Dr. Jones deviated from Acells
» » instructions.
» » In the second post, Costanza says that Dr. Jones followed Acell’s
» » instructions, but the patient didn’t.
» »
» »
» » Regarding repetition of experiment:
» » Jones expressed repeatedly his willingness to repeat the experiment if
» it
» » failed first time. But he finally said that Acell didn’t provide an
» » alternative protocol, so he wouldn’t try again.
» »
» »
» » Spanish Dude’s veredict: Unless further evidence is presented, I
» » vouch for Jones. Sorry but my impression is that Acell reps, Manning
» and
» » Rodney Bosley did a very poor job.
» »
» »
» » p.d: next on a separate post, I post all the messages by Jones and
» » Costanza
»
» In the Hitzig interview posted here the other day, Hitzig spoke of an HT
» doc, whose name Hitzig couldn’t remember, but whom Hitzig believed was in
» Canada, and how this doctor used ACell on a strip scar and the results were
» equivocal.
»
» Hitzig went on to say that doctor had not followed the proper use of
» ACell, saying among other things that the wound should be kept moist and
» yucky until it heals, which would mean no scabbing. And otherr things I
» forgot.
»
» Whose to blame? I dunno.
»
» Could be nobody. Could be ACell didn’t know the best way to use the stuff
» on scalp skin until more recently.

Answer: It’s Spanish DUD. He persecuted Willy; now he’s back pedaling on Acell.
Analysis complete.

» I have compiled all the posts regarding this issue, and here is my
» analysis:
»
»
» According to Jones,
» 1. Jones followed Acell’s instructions exactly. Jones insists on
» this several times.
» 2. Acell didn’t provide an alternative method for a second try, and
» that is why the project was abandoned.
»
» According to Costanza (who contacted Acell):
» Costanza posted 2 posts, which contradict each other:
» -1st. Jones deviated from Acell instructions. Acell wanted the
» wound bandaged and moist, and powder reaplied. Jones simply let the scar to
» form alone.
» -2nd. Jones followed Acell instructions but patient didn’t: Acell
» wanted wound not bandaged, just keeping moist by gauzes, (no mention of
» reapplying powder).
» The patient didn’t apply gauzes, the wound dried, and experiment failed.
»
» As you see, Costanza contradicts himself on who is to blame, and on the
» set of instructions provided by Acell.
»
» Regarding the instructions provided by Acell:
» In the first post, Costanza says that Acell wanted the wound bandaged and
» moist, and powder reaplied several times.
» But in the second post, Costanza says that Acell just wanted the wound
» moist by applying wet gauzes, and doesn’t mention if the powder has to be
» reapplied.
» (no mention of how the gauzes are supposed to be applied overnight).
»
» Regarding who is to blame:
» In the first post, Costanza says that Dr. Jones deviated from Acells
» instructions.
» In the second post, Costanza says that Dr. Jones followed Acell’s
» instructions, but the patient didn’t.
»
»
» Regarding repetition of experiment:
» Jones expressed repeatedly his willingness to repeat the experiment if it
» failed first time. But he finally said that Acell didn’t provide an
» alternative protocol, so he wouldn’t try again.
»
»
» Spanish Dude’s veredict: Unless further evidence is presented, I
» vouch for Jones. Sorry but my impression is that Acell reps, Manning and
» Rodney Bosley did a very poor job.
»
»
» p.d: next on a separate post, I post all the messages by Jones and
» Costanza

Dr Jones stated his willingness to try Acell once more provided he was given new protocols. Might I suggest we stop humoring Spanish Dud’s self-serving posts in favor of bringing the new protocols to Dr Jone’s attention?

» In the Hitzig interview posted here the other day, Hitzig spoke of an HT
» doc, whose name Hitzig couldn’t remember, but whom Hitzig believed was in
» Canada, and how this doctor used ACell on a strip scar and the results were
» equivocal.
»
» Hitzig went on to say that doctor had not followed the proper use of
» ACell, saying among other things that the wound should be kept moist and
» yucky until it heals, which would mean no scabbing. And otherr things I
» forgot.
»
» Whose to blame? I dunno.
»
» Could be nobody. Could be ACell didn’t know the best way to use the stuff
» on scalp skin until more recently.

» Answer: It’s Spanish DUD. He persecuted Willy; now he’s back
» pedaling on Acell.
» Analysis complete.

I didn’t expect more of you. Thanks for your effort, though.

»
»
» » I have compiled all the posts regarding this issue, and here is my
» » analysis:
» »
» »
» » According to Jones,
» » 1. Jones followed Acell’s instructions exactly. Jones insists on
» » this several times.
» » 2. Acell didn’t provide an alternative method for a second try,
» and
» » that is why the project was abandoned.
» »
» » According to Costanza (who contacted Acell):
» » Costanza posted 2 posts, which contradict each other:
» » -1st. Jones deviated from Acell instructions. Acell wanted the
» » wound bandaged and moist, and powder reaplied. Jones simply let the scar
» to
» » form alone.
» » -2nd. Jones followed Acell instructions but patient didn’t:
» Acell
» » wanted wound not bandaged, just keeping moist by gauzes, (no mention of
» » reapplying powder).
» » The patient didn’t apply gauzes, the wound dried, and experiment
» failed.
» »
» » As you see, Costanza contradicts himself on who is to blame, and on the
» » set of instructions provided by Acell.
» »
» » Regarding the instructions provided by Acell:
» » In the first post, Costanza says that Acell wanted the wound bandaged
» and
» » moist, and powder reaplied several times.
» » But in the second post, Costanza says that Acell just wanted the wound
» » moist by applying wet gauzes, and doesn’t mention if the powder has to
» be
» » reapplied.
» » (no mention of how the gauzes are supposed to be applied overnight).
» »
» » Regarding who is to blame:
» » In the first post, Costanza says that Dr. Jones deviated from Acells
» » instructions.
» » In the second post, Costanza says that Dr. Jones followed Acell’s
» » instructions, but the patient didn’t.
» »
» »
» » Regarding repetition of experiment:
» » Jones expressed repeatedly his willingness to repeat the experiment if
» it
» » failed first time. But he finally said that Acell didn’t provide an
» » alternative protocol, so he wouldn’t try again.
» »
» »
» » Spanish Dude’s veredict: Unless further evidence is presented, I
» » vouch for Jones. Sorry but my impression is that Acell reps, Manning
» and
» » Rodney Bosley did a very poor job.
» »
» »
» » p.d: next on a separate post, I post all the messages by Jones and
» » Costanza

Spanish Dude,

I did mention Hitzig…although at first, I wasn’t sure of his name. Here is my first post about him:

There is another doctor in New York who is testing the product…I don’t know what his name is. Another forum member has e-mailed me about this doctor.

Here is the link to that post:

http://www.hairsite.com/hair-loss/forum_entry-id-39431.html

Here is a copy of the e-mail (I removed the names to protect people’s identities. I didn’t remove Hitzig’s name…it was never mentioned)

Acell Saturday, July 19, 2008 11:45 PM From: “xxxxxxxxxx” <xxxxxxxxxxhotmail.com>Add sender to Contacts
To: billy550catyahoodotcom

Hello Bill,

Your brother gave me your email. I have a hair transplant doctor who wants to try Acell as soon as it released. The first thing he wanted to try is plucking hair and dipping them in Acell and implanting them .

Acell is interested in hair transplants so I do not think there will be a problem getting it when its released.

Here is a reply I got. Please do not post this----I do not want a bunch of guys calling him.

Dear xxxx,

Thank you for your interest in Acell.

We do not currently have product available for human use, but we expect it within the year.

This is an area of interest for ACell, and I would like to speak with you about potential for our product in this area.

Please register on our website to stay up with the news.

Please give me the name of your facility and if you have done research in the area of hair regrowth.

Thanks again for your interest.

Sincerely,

xxxxxxxxxx

ACell, Inc.

5850 Waterloo Rd.

Suite 140

Columbia, Md. 21045

I think it will also work in the donor area for strip and FUE, Please let me know when Acell is ready for release.

Best xxxxx

If he wasn’t talking about Dr. Hitzig…IT IS A REAL COINCIDENCE!!!

I also mentioned Dr. Hitzig here (although I spelled his name wrong):

There is a company called Acell which has released an ExtraCellular Matrix (ECM) that POSSIBLY has the potential to regenerate removed donor tissue and hair in a HT. Several doctors (Dr. Umar, Dr. Jones, Dr. Hitzgee (sp?)) have already tried this product and we are waiting for results. I sent an e-mail to a list of doctors (also listed) about the product trying to spark an interest in them to at least test the product and a few of them are doing so. Here is the copy of the e-mail that I sent to them and the list of doctors that it was sent to:

Here is the link:

http://www.hairsite.com/hair-loss/forum_entry-id-40523.html

I also mentioned him here (again, spelling his name wrong):

http://www.hairsite.com/hair-loss/forum_entry-id-40579.html

I didn’t know about Cooley’s interest…I think he only became interested after Hitzig showed him some results.

I don’t want to criticize Dr. Jones, but there is one issue that I would like to point out regarding this issue. I appreciate that he tried Acell and shared his results with this forum. I personally believe that he made mistakes in his trial and I don’t know why he didn’t make another attempt.

The issue that I would like to point out is that I feel Dr. Jones was not completely forthcomming with how he came to learn about Acell. If you read his blog regarding Acell he states:

"I first heard of Acell four months ago, learned it is a product that has been used in Veterinary medicine for years. Acell provides a basement membrane surface which allows for epithelial cell growth, or more simply skin regeneration. It caught my interest because in veterinary use it not only regenerates skin, but regenerates skin with normal hair follicles. Further, Acell has been approved for wound care in humans, and in patients where it has been used, the hair follicles regenerate as well as the skin. Excessive scarring is a problem all hair restoration surgeons encounter. It is always a concern of the patient, that their donor site scar will be unattractive and visible. I immediately wondered what great things this would do to help repair patients old scars and I couldn’t help but imagine that using Acell in the hair transplant procedure would possibly produce an undetectable scar, and perhaps to even regenerate the donor area.

Here is the link to that:

http://www.hairsite.com/hair-loss-articles/391-acell-wound-regeneration.htm

He didn’t have to IMAGINE what possibilities Acell had…THEY WERE DESCRIBED TO HIM IN BLACK AND WHITE! (in the original e-mail sent to him).

Here is the section of the original e-mail that I am speaking of:

Recently, in researching hair restoration on a website called Hairsite, I’ve been informed of a company named Acell. This company has developed a product called an extracellular matrix that is amazing in it’s capabilities for regeneration. It has been used extensively in vet. medicine for wound care but has recently been released for human use. In previous cases (in vet medicine), the Acell material not only regenerated the skin tissue of a wounded animal but also REGENERATED THE HAIR in the wounded area. If this can be replicated in humans, it would solve the limiting factor of donor hair in regards to a hair transplant. That is, the doctor could perform a conventional hair transplant, apply the Acell extracellular matrix to the wound (rather than stitching it up) and allow the tissue AND HAIR to regenerate, thus providing a LIMITLESS DONOR SUPPLY. I have since had several conversations with Acell and they have informed me that they are confident that the extracellular matrix will be capable of doing this. If this does prove to be the case, hair transplant doctors will finally be able provide the full head of hair that their patients seek, thus opening a WHOLE NEW MARKET OF PROSPECTIVE PATIENTS.

Here is the link to that:

http://www.hairsite.com/hair-loss/forum_entry-id-35124-page-0-category-1-order-time.html

I GUESS IT’S NOT TOO POPULAR TO ADMIT THAT YOU GOT AN IDEA ABOUT A MEDICAL PROCEDURE FROM A NON-MEDICAL PROFESSIONAL ON AN INTERNET FORUM…TOTAL HONESTY…NOT REALLY!

I thought you said that I didn’t mention Cooley or Hitzig not vice versa…it has been a long day :frowning:

Anyways, I did notice that Hitzig stated that he became aware of Acell in 2004, but I find this hard to believe for a couple reasons.

  1. when I originally contacted Acell (in 2007) about using their ECM in hair transplants, they knew very little about HT’s. I would think that if they were dealing Hitzig since 2004, they would have know SOMETHING about HT’s

Here is a link to a post I made in 2008 about this original conversation:

http://www.hairsite.com/hair-loss/forum_entry-id-30763.html

  1. I was speaking to another forum member (via e-mail) about a doctor he was dealing with in NY that wanted to try using plucked hairs with Acell. Here is a copy of the e-mail (I removed names to protect identities…Hitzig’s name was not removed…it was never mentioned):

Acell Saturday, July 19, 2008 11:45 PM From: “xxxxxxxxxx” <xxxxxxxxxxhotmail.com>Add sender to Contacts
To: billy550catyahoodotcom

Hello Bill,

Your brother gave me your email. I have a hair transplant doctor who wants to try Acell as soon as it released. The first thing he wanted to try is plucking hair and dipping them in Acell and implanting them .

Acell is interested in hair transplants so I do not think there will be a problem getting it when its released.

Here is a reply I got. Please do not post this----I do not want a bunch of guys calling him.

Dear xxxx,

Thank you for your interest in Acell.

We do not currently have product available for human use, but we expect it within the year.

This is an area of interest for ACell, and I would like to speak with you about potential for our product in this area.

Please register on our website to stay up with the news.

Please give me the name of your facility and if you have done research in the area of hair regrowth.

Thanks again for your interest.

Sincerely,

xxxxxxxxxx

ACell, Inc.

5850 Waterloo Rd.

Suite 140

Columbia, Md. 21045

I think it will also work in the donor area for strip and FUE, Please let me know when Acell is ready for release.

Best xxxxx

I don’t know for sure if he was talking about Dr. Hitzig, but if he was not…IT IS A REAL COINCIDENCE! I don’t know of any other doctors that were using plucked hairs. Also, if this guy was speaking of Dr. Hitzig, and Dr. Hitzig was in contact with Acell since 2004…why were they asking me to let them know when Acell was released? Why were they speaking to me at all?

In Dr. Hitzig’s defense, he never dealt personally with me, so he wouldn’t know my name and PERHAPS he was just “off” on his dates…he did mention that he learned of it from a patient who did alot of “research” on the internet.

I think Dr. Cooley became interested in Acell when he saw Dr. Hitzig’s success, so he would never connect me with Acell.

Take Care,
Bill

Time will tell if Drs. Hitzig, Cooley, Rassman, ect…provide an effective treament with Acell to provide a better supply (hopefully limitless) for HT patients. I am cautiously optimistic but don’t want to get my (or anyone else’s) hopes up too much yet…WE WILL JUST HAVE TO WAIT AND SEE.

The fact that Dr. Jones’ attempt at using Acell didn’t prove effective at regenerating removed donor tissue/hair cast a negative light on Acell and made the forum members (myself included) lose hope in this product. Now, Dr. Hitzig and Dr. Cooley are claiming success with the use of Acell utilizing a different technique. This is why I felt it was so important to contact as many doctors as possible about this product…to prevent a false negative result from it. Here is the post:

http://www.hairsite.com/hair-loss/forum_entry-id-35201.html

Hi Willy:
yes, now you got me right. I was expecting Dr. Hitzig or Cooley mentioning you, considering that you emailed dozens of doctors about Acell, from Jul2008, before any doctor started trying it (Hitzig says he was the first one to try, on 19-Sept-2008 or shortly afterwards).

Re. your email, lets see if I understand it well:
A doctor from NY, around Jul-19,2008, who wanted to try Acell on plucked hairs? Well, that must be Hitzig, no doubt.
And this doctor… how did he express himself? Did he say that he already had a plan to use Acell, with already stablished contacts, or rather was he seeking to stablish contact with Acell from zero? Was this doctor interested in contacting you, Willy, to learn from Acell?

Hitzig has told Kobren that he first knew of Acell in 2004, thanks to a “researchy patient” who already knew it, and this patient suggested that Acell could be a good help for the plucked hairs. Hitzig says that he contacted Acell then in 2004, but as the product was not yet FDA-approved for humans, they decided to wait. Hitzig says that they (acell and Hitzig) kept in touch, and they developed plans together over the next few years, until Sept19,2008, when Acell called Hitzig to tell him that they got FDA-approval, and Hitzig started experimenting.

So, the 2004 date is not “off” at all. He says that he was in touch with Acell “over the years” until FDA approval in Sept-2008.
Mmmmhh…

(lets remember that you started emailing doctors in July 2008, I have just checked).

» I thought you said that I didn’t mention Cooley or Hitzig not vice
» versa…it has been a long day :frowning:
»
» Anyways, I did notice that Hitzig stated that he became aware of Acell in
» 2004, but I find this hard to believe for a couple reasons.
»
» 1) when I originally contacted Acell (in 2007) about using their ECM in
» hair transplants, they knew very little about HT’s. I would think that if
» they were dealing Hitzig since 2004, they would have know SOMETHING about
» HT’s
»
» Here is a link to a post I made in 2008 about this original conversation:
»
» http://www.hairsite.com/hair-loss/forum_entry-id-30763.html
»
»
» 2) I was speaking to another forum member (via e-mail) about a doctor he
» was dealing with in NY that wanted to try using plucked hairs with Acell.
» Here is a copy of the e-mail (I removed names to protect
» identities…Hitzig’s name was not removed…it was never mentioned):
»
»
» Acell Saturday, July 19, 2008 11:45 PM From: “xxxxxxxxxx”
» <xxxxxxxxxxhotmail.com>Add sender to Contacts
» To: billy550catyahoodotcom
»
» Hello Bill,
»
» Your brother gave me your email. I have a hair transplant doctor who wants
» to try Acell as soon as it released. The first thing he wanted to try is
» plucking hair and dipping them in Acell and implanting them .
»
» Acell is interested in hair transplants so I do not think there will be a
» problem getting it when its released.
»
» Here is a reply I got. Please do not post this----I do not want a bunch of
» guys calling him.
»
»
»
» Dear xxxx,
»
»
»
»
» Thank you for your interest in Acell.
»
»
»
» We do not currently have product available for human use, but we expect it
» within the year.
»
»
»
» This is an area of interest for ACell, and I would like to speak with you
» about potential for our product in this area.
»
»
»
» Please register on our website to stay up with the news.
»
»
»
» Please give me the name of your facility and if you have done research in
» the area of hair regrowth.
»
»
»
» Thanks again for your interest.
»
»
»
» Sincerely,
»
»
»
» xxxxxxxxxx
»
» ACell, Inc.
»
» 5850 Waterloo Rd.
»
» Suite 140
»
» Columbia, Md. 21045
»
»
»
» I think it will also work in the donor area for strip and FUE, Please let
» me know when Acell is ready for release.
»
»
»
» Best xxxxx
»
»
»
» I don’t know for sure if he was talking about Dr. Hitzig, but if he was
» not…IT IS A REAL COINCIDENCE! I don’t know of any other doctors
» that were using plucked hairs. Also, if this guy was speaking of Dr.
» Hitzig, and Dr. Hitzig was in contact with Acell since 2004…why were
» they asking me to let them know when Acell was released? Why were they
» speaking to me at all?
»
» In Dr. Hitzig’s defense, he never dealt personally with me, so he wouldn’t
» know my name and PERHAPS he was just “off” on his dates…he did mention
» that he learned of it from a patient who did alot of “research” on the
» internet.
»
» I think Dr. Cooley became interested in Acell when he saw Dr. Hitzig’s
» success, so he would never connect me with Acell.
»
» Take Care,
» Bill

Oooh, Willy, I didn’t know about this.
I thought that Jones was doing this experiment in touch with you, after you contacted him.
Are you telling me that Jones did the experiment without contacting you, without mentioning you, and pretending to have had the idea himself?
Did he reply to your emails?
It is ovious that he, at least, learned it from the internet forums, so he should have acknowledged so. And if he had the idea before your emails, he should have contacted you to tell you. Sidn’t he contact you?

» I don’t want to criticize Dr. Jones, but there is one issue that I would
» like to point out regarding this issue. I appreciate that he tried Acell
» and shared his results with this forum. I personally believe that he made
» mistakes in his trial and I don’t know why he didn’t make another attempt.
»
»
» The issue that I would like to point out is that I feel Dr. Jones was not
» completely forthcomming with how he came to learn about Acell. If you read
» his blog regarding Acell he states:
»
» "I first heard of Acell four months ago, learned it is a
» product that has been used in Veterinary medicine for years. Acell provides
» a basement membrane surface which allows for epithelial cell growth, or
» more simply skin regeneration. It caught my interest because in veterinary
» use it not only regenerates skin, but regenerates skin with normal hair
» follicles. Further, Acell has been approved for wound care in humans, and
» in patients where it has been used, the hair follicles regenerate as well
» as the skin. Excessive scarring is a problem all hair restoration surgeons
» encounter. It is always a concern of the patient, that their donor site
» scar will be unattractive and visible. I immediately wondered what great
» things this would do to help repair patients old scars and I couldn’t help
» but imagine that using Acell in the hair transplant procedure would
» possibly produce an undetectable scar, and perhaps to even regenerate the
» donor area.
»
» Here is the link to that:
»
» http://www.hairsite.com/hair-loss-articles/391-acell-wound-regeneration.htm
»
»
»
»
» He didn’t have to IMAGINE what possibilities Acell had…THEY WERE
» DESCRIBED TO HIM IN BLACK AND WHITE! (in the original e-mail sent to him).
»
» Here is the section of the original e-mail that I am speaking of:
»
» Recently, in researching hair restoration on a website called
» Hairsite, I’ve been informed of a company named Acell. This company has
» developed a product called an extracellular matrix that is amazing in it’s
» capabilities for regeneration. It has been used extensively in vet.
» medicine for wound care but has recently been released for human use. In
» previous cases (in vet medicine), the Acell material not only regenerated
» the skin tissue of a wounded animal but also REGENERATED THE HAIR in the
» wounded area. If this can be replicated in humans, it would solve the
» limiting factor of donor hair in regards to a hair transplant. That is, the
» doctor could perform a conventional hair transplant, apply the Acell
» extracellular matrix to the wound (rather than stitching it up) and allow
» the tissue AND HAIR to regenerate, thus providing a LIMITLESS DONOR SUPPLY.
» I have since had several conversations with Acell and they have informed me
» that they are confident that the extracellular matrix will be capable of
» doing this. If this does prove to be the case, hair transplant doctors will
» finally be able provide the full head of hair that their patients seek,
» thus opening a WHOLE NEW MARKET OF PROSPECTIVE PATIENTS.
»
» Here is the link to that:
»
» http://www.hairsite.com/hair-loss/forum_entry-id-35124-page-0-category-1-order-time.html
»
»
» I GUESS IT’S NOT TOO POPULAR TO ADMIT THAT YOU GOT AN IDEA ABOUT A MEDICAL
» PROCEDURE FROM A NON-MEDICAL PROFESSIONAL ON AN INTERNET
» FORUM…TOTAL HONESTY…NOT REALLY!

No…Jones didn’t contact me. I wasn’t in contact with Hitzig either. I believe that Hitzig was in contact with the forum member who sent me the e-mail because it is too coincidental that the doc he was contacting was using a plucking procedure and Hitzig is using a plucking procedure and both his doc and Hitzig are from NY. I personally don’t believe that Hitzig was in contact with Acell in 2004. I believe that Dr. Hitzig’s internet researcher is the Hairsite forum member who e-mailed me and that his initial interest arose from posts on this forum. I could be wrong about that…but I doubt it. If Hitzig were in contact with Acell (for 3 years), why did they know so little about HT’s and I would think that they would have told me that they already have a relationship with a doctor (rather than speaking with me…a layperson). Also, if the e-mail I recieved were in regards to Dr. Hitzig (and Hitzig had a 3 year relationship with Acell)…why would this person ask me to let him know when it was released? Doesn’t make sense to me. Again, I personally believe that it is not to popular that (as a doctor) you learned of a medical procedure from a hairloss forum full of non-medical professionals…that is just my opinion.

Either way, I give Dr. Hitzig ALL THE CREDIT IN THE WORLD in developing his plucking technique. When I first read that e-mail (reguarding plucking), I thought that they were crazy and that it wouldn’t work…looks like they might be proving me wrong…I HOPE!!! Dr. Hitzig definately was “thinking outside of the box” with that one!

The only people that I maintained any contact with was Acell and Dr. Arvind. Dr. Arvind wanted to try Acell, but couldn’t get it because he is in India. I haven’t spoken to him in a long while, so I don’t know if he can get it now or not.

So you emailed dozens of doctors and only Dr. Arvind replied to you!!!???

Willy, why don’t you email Acell to ask about the 2004 claim? (although maybe they don’t want to confront Hitzig)

» No…Jones didn’t contact me. I wasn’t in contact with Hitzig either. I
» believe that Hitzig was in contact with the forum member who sent me the
» e-mail because it is too coincidental that the doc he was contacting was
» using a plucking procedure and Hitzig is using a plucking procedure and
» both his doc and Hitzig are from NY. I personally don’t believe that
» Hitzig was in contact with Acell in 2004. I believe that Dr. Hitzig’s
» internet researcher is the Hairsite forum member who e-mailed me and that
» his initial interest arose from posts on this forum. I could be wrong
» about that…but I doubt it. If Hitzig were in contact with Acell (for 3
» years), why did they know so little about HT’s and I would think that they
» would have told me that they already have a relationship with a doctor
» (rather than speaking with me…a layperson). Also, if the e-mail I
» recieved were in regards to Dr. Hitzig (and Hitzig had a 3 year
» relationship with Acell)…why would this person ask me to let him know
» when it was released? Doesn’t make sense to me. Again, I personally
» believe that it is not to popular that (as a doctor) you learned of a
» medical procedure from a hairloss forum full of non-medical
» professionals…that is just my opinion.
»
» Either way, I give Dr. Hitzig ALL THE CREDIT IN THE WORLD in developing
» his plucking technique. When I first read that e-mail (reguarding
» plucking), I thought that they were crazy and that it wouldn’t
» work…looks like they might be proving me wrong…I HOPE!!! Dr.
» Hitzig definately was “thinking outside of the box” with that one!
»
» The only people that I maintained any contact with was Acell and Dr.
» Arvind. Dr. Arvind wanted to try Acell, but couldn’t get it because he is
» in India. I haven’t spoken to him in a long while, so I don’t know if he
» can get it now or not.

Most importantly, I think that Cooley and Hitzig have become public because there are other doctors trying, and they wanted to be the first ones. Even if it is too soon to ascertain success.

» Time will tell if Drs. Hitzig, Cooley, Rassman, ect…provide an
» effective treament with Acell to provide a better supply (hopefully
» limitless) for HT patients. I am cautiously optimistic but don’t want to
» get my (or anyone else’s) hopes up too much yet…WE WILL JUST HAVE TO
» WAIT AND SEE.
»
» The fact that Dr. Jones’ attempt at using Acell didn’t prove effective at
» regenerating removed donor tissue/hair cast a negative light on Acell and
» made the forum members (myself included) lose hope in this product. Now,
» Dr. Hitzig and Dr. Cooley are claiming success with the use of Acell
» utilizing a different technique. This is why I felt it was so important to
» contact as many doctors as possible about this product…to prevent a
» false negative result from it. Here is the post:
»
»
» http://www.hairsite.com/hair-loss/forum_entry-id-35201.html

Spanish Dude,

I had several replies from doctors about Acell…….but, Dr. Arvind was the only doctor that continued a dialog with me.

Here is the original e-mail that I received from Dr. Arvind:

Dear Bill,
From what I have read on the website and the cases that they have shown, I am optimistic about the product.
Like you, I too feel that if this product works the way they claim it does, then it can revolutionize HT.
After all, the limiting factor in HTs today is the donor.

My problem is that due to the distance and the time difference I am not possible to contact the company.

Is it possible to obtain a sample of the product? Can you find out how close they are to launching the product in the market, for medical uses other than hair transplants.

Thanks for your effort and will appreciate any help.
Regards,
Dr. A

We had several conversations over the next month or two about Acell, but Dr. Arvind was not able to get a shipment of the product because he was in India. I haven’t spoken with him in a while, and I really don’t know where he stands on trying Acell at this point.

I had several other “one time replies” from doctors when I e-mailed them about Acell. They replied to my original e-mail again, but I didn’t have continued conversations with them. I contacted Acell and sent them copies of those replies………here is a copy of the e-mail that I sent to Acell:

Hi XXXX,

I e-mailed over 60 doctors about Acell. I received several responses. I thought you might be interested so I am going to copy/paste them to this e-mail. There were two responses that were sent to another forum member also. I will include a paraphrased version of those.

Take Care,
Bill XXXXXX
Pittsburgh, PA

P.S. Sorry, I tried to alternate colors to make it easier to read…but not all of them would let me do it.

“Dr. Joseph Gallagher” jcg@drjgallagher.com

THANK YOU FOR YOUR INPUT HOWEVER, AS ANYONE WORTH HIS SALT I WOULD HAVE
TO EVALUATE THIS PRODUCT WITH SCIERNTIFIC DATA
WHICH WOULD INCLUDE A DOUBLE BLIND STUDY.
i THINK I WILL ASK THE COM[ANY IF THEY WOULD LIKE TO PARTICIPATE IN RESERCH.
iN ADDITION THIS PRODUCT WILL BE DISCUSSED AT THE HAIR SOCIETY MEETING
THIS FALL

THANK FOR YOUR INPUT

“Paul Rose” paultrose@yahoo.com

Dear Mr XXXXXX
Thanks for the email. I looked at the photos. the wound healing is very impressive.
I am not sure that the material promoted hair growth. I think that what we are seeing are the effects of wound contraction more than hair growth
Also canine fur grows differently than primate hair.
In any case the material may be very useful. I think they need to do a controlled study in humans with IRB approval.
It might be interesting to try in humans who undergo scalp surgery for removal of a skin cancer. In some of these situations we allow the wound to granulate in anyway.

Paul T. Rose MD, JD Past President ISHRS Board of Trustees, ISCLS cell 612 965 4247 office 813 259 9889 office 813 924 4247

“DrCarlBazan” doctor@itzan.com

Dear Bill

I am interested in any and all technologies that can improve the outcome of HT procedures and, better yet, improve/enlarge or multiply donor supply.

Of course, in my case it is very difficult to accept any research program for the improvement of hair loss patients because I spent many years trying methods to multiply hair and I failed in providing safety and consistency. After I announced that in my opinion I could not do it because it was beyond my budget (100% private funds, never obtained a single dollar from the donations or partmerships intended) I was severly attacked by a few members of known hairloss and HT boards.

Same happened to Conradus Gho and other doctors that on teir private funds attempted to multiply donor supply and failed.
So if this new case (acell) fails to achieve the expected regrowth it will result that for same reason people will attack the researcher as it is our fault that it ultimately does not work as originally planned.

I thank the kindness of your invitation and wish you the best luck in this great idea (acell).

Truly,
Carl Bazan, MD

FUE HT / Mexico

Dr. Greco grecophd@comcast.net
Thank you Bill for this information and I can see the excitement when you see the photos of animal wounds and hair re growth. I have also given you Case Studies of Equine wounds and rapid healing with hair regrowth with PRP and our natural protein matrix, but regrowing hair from a wound on an animal and regrowing hair after the follicle is removed from a human is very different.

We will continue in our research, that is also FDA approved and based our experience in 28,000 human procedures and the answers we are all working toward may fall somewhere in the middle. Lets keep in contact and share information as we are all in this together.

Dr. Cole michelle@forhair.com

Good Morning Bill,
I have forwarded this information to Dr. Cole and thanks… We have actually heard quite a bit about this product especially in the last few weeks…
Do you work for this company?

Thanks

When I responded that I do not work for the company:

Thanks Bill… I was just curious… we got so many sales people posing as patient
Thanks and we are taking a look at Acell…

Frank DeCarlo (Hairclub) fdecarlo@hcfm.com

Mr. XXXXXXX,
Thank you for the informative pieces of information. I will certainly forward this on to our medical team as well as review the materials myself. I too hope that an unlimited donor supply would be available. This would be a wonderful breakthrough.

Regards,
DeCarlo

“Alan J Bauman MD (Bauman Medical)” urgent@baumanmedical.com

Bill,
Thank you for your email. The video and photos were very interesting.
If I am not mistaken, ACell’s products currently consist of a porcine-derived protein sheet or matrix. There are a number of these types of products that have been on the market for years. In my training in General Surgery over 15 yrs ago, we used quite a bit of these types of products to help heal large surface area wounds all over the human body with good success. Personally, seven yrs ago in my hair restoration practice, I used a porcine sheet for a patient with a very large area of scalp which had been injured and removed down to the skull. Amazing regrowth of skin occurred via islands of tissue proliferating up through the exposed surface of the skull finally coalescing into complete (yet thin) coverage in a few months. Many of the natural components of skin were noted in the regrowth of these human patients I’ve seen personally. However, sadly, not hair follicles. That patient I personally treated here in Florida eventually needed transplants to cover the area.

With regard to patients achieving their goals with current levels of hair transplant ‘technology’ I believe your statement is partly false. We know through rigorous research projects undertaken by the ISHRS (International Society of Hair Restoration Surgery) that the average patient today reaches and maintains his hair restoration goal in an average of two sessions. My dad, a Norwood 7, needed three, btw. This is mainly due to the following factors:

1)Large amounts of follicles are moved in each transplant session.
2)A high density of small incisions often allow a ‘one pass’ result in bare areas
3)Medical treatments, when used correctly, stop the hair loss progression in the non-transplanted hair at least 90% of the time
4)The majority of patients treated today have never had old-style transplants (which depleted and wasted precious donor hair).

In other words, if you were completely satisfied after you painted your house with two coats of ‘permanent,’ weather-proof paint, what good would an unlimited supply of paint do for you?

A recent ‘cover’ article in The Hair Transplant Forum (our most prominent journal), in fact, highlighted the point that most patients today won’t really need some kind of ‘hair multiplication’ to achieve a satisfying result, despite the media’s fascination with that kind of technology. The key to treating hair loss is not really creating new follicles, but reversing and preventing their miniaturization at an early stage, before the hair loss is severe.

Therefore, it is my prediction that the recently available genetic testing for hair loss, will be the most significant breakthrough in hair loss this year.

Sincerely,
Dr. B.

“Hasson and Wong” info@hassonandwong.com

Bill,
Thank you for your email.

The doctors are aware of Acell and have been investigating it. I will forward your email to them as I am sure they will find the links very useful.

Thank you
Christina
Hasson & Wong
Phone: 604-739-4247
Fax: 604-739-4244
Toll Free: 1-800-859-2266

“I am already receiving samples of the material.
Thanks”

  • from Prohairclinic:

"We have very good relations with dr. Jones in Ontario. He is going to evaluate the product and report.
Depending on his findings we may be interested in using the product.

Greetings,
Bart
Prohairclinic"

I never spoke (via e-mail or on the phone) with Dr. Jones, Hitzig or Cooley. I e-mailed Dr. Jones about Acell, but never received a reply from him. I never contacted Dr. Hitzig……but, as I previously stated……I believe the other forum member (who contacted me about a doctor in NY who wanted to use Acell with plucked hair) was in contact with Dr. Hitzig (that is my opinion).

As far as contacting Acell as asking them about their 2004 claim……for what reason? What would it change? I personally believe that Dr. Hitzig learned about Acell from the “buzz” created on this forum…….but either way……HE IS THE ONE WHO THOUGHT OF USING IT WITH PLUCKED HAIRS AND MAY HAVE FOUND A WAY TO INCREASE OUR DONOR SUPPLY. If Acell does turn out to provide us with a breakthrough in hair transplant technology, I would like to think that I played a small part in this advancement (for my own ego’s sake………and I believe in my heart that I did), but my original and main reason for contacting the doctors about Acell has not changed…….I JUST WANT A FULL HEAD OF HAIR AGAIN!!!

Take Care,
Bill

…they’ve got a thing goin’ on… :slight_smile:

» Either way, I give Dr. Hitzig ALL THE CREDIT IN THE WORLD in developing
» his plucking technique. When I first read that e-mail (reguarding
» plucking), I thought that they were crazy and that it wouldn’t
» work…looks like they might be proving me wrong…I HOPE!!! Dr.
» Hitzig definately was “thinking outside of the box” with that one!
»

I too am most interested in autocloning using plucked donor, that is as good as hair multiplication in my opinion, I hope other doctors will try this too.