I spoke with Acell today and got answers to most of the questions asked by forum members.
- What denatures the ecm?
- Would the slightest denaturing put fibrous tissue were a hair follicle would be?
You should not use TOPICAL antibiotics or cleansers. The ECM has antibacterial properties already. Any denaturing would probably generate fibrous tissue where a hair follicle would be.
Have they seen Dr. Jones’ blog, what do they think of the results so far and is this typical?
Any incidence of side effects, rejection from the immune system, complications of any kind ? Doesn’t have to be hair related, but in general.
They have seen the blog and at this point, they feel that it looks like scar tissue has formed. Dr. Jones plans on trying several techniques to determine which procedure will be the most optimal.
They know of no incidence of side of effects or rejection at this point. Even though the use of Acell is fairly new at this point, ECM’S have been used on over 500,000 patients with no side effects or rejection. There is no rejection because no cells / cell markers from the pig are contained in the ECM. Our bodies accept the collegen / growth factors…similar to the TH2 response in pregnant women (there body sees the fetus as a foreign body but does not reject it).
please ask them if they intend to release an acell gel, if so when, thanks
Possible release of a Topical Gel but no timeframe at this point.
Do you have a confirm from some doctors using acell about a regrowth of hairs?
None in the donor area at this point…it’s too early at this point. One doctor did use Acell in conjunction with a BHT (beard hair). Growth of the hair was accomplished with the use of Acell and a section (where Acell was not used) had no growth.
When do they expect photos to be uploaded to their site?
Would hyaluronic acid (HA) denature the acell ecm? I am wondering if keeping an acell covered wound moist with HA in addition or instead of saline would be a better option than just saline alone. (Willy, if unfamiliar with HA, do a simple google search and you’ll understand why I ask this question.)
Will the acell gel be an injectable or just a topical.
Photos should be posted on the website fairly soon…but no exact timeframe.
HA acid should not be used with Acell
The gel will be a topical…no time frame at this point.
Have they talked with Dr. Jones about or do they know what Dr. Jones’ plans are for future testing with Acell? When will he start a new experiment?
Dr. Jones does plan on trying different protocols but no definate plans at this point.
See if they’ll confirm if Acell has ever regrown functioning hair follicles on ANY part of the human body.
They are not aware if Acell has ever regrown functioning hair follicles on any part of the human body. They have primarily treated (at this point) parts of the body where you wouldn’t see hair…fingers, diabetic ulcers,ect…
Willy, please ask what type of physicians, other than HT docs, are currently experimenting with acell.
I know of only one cosmetic surgeon (the one in New York) who used acell once and that was for a scar on the forehead. So please find out if he was the only other PS or derm using acell. Also, please ask when he expects photos from this patient (mentioned above). It’s been 6 months since the treatment and every time I speak with Mike Manning he says that he expects new photos shortly.
It has been used by plastic surgeons, hand centers, the military, ect…
The protocol calls for Acell to be applied weekly. You can bandage the area or apply hydrogel to keep the wound moist. In the future, they will have layered sheets (they will stay in longer before being absorbed.
At this point, they are still confident with their product…time will tell.
Hopefully this answers most of the questions you guys have. I don’t plan on calling them for another month or two.