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about Circumin & ARs in general:
How is any of the systemic stuff gonna target the scalp skin alone?
Wouldn’t all these systemic method of reducing AR activity (the Vitamin E thing for example) just be a more roundabout way of functionally decreasing all your androgens in your system?
Popping pills to affect ARs in some way . . . it all sounds kind of like just a different way to get the effects of oral Spiro to me. No thanks.
C urcumin has a number of biological actions in addition to being an anti-oxidant. It also inhibits 5a-reductase, which converts testosterone
to 5a-dihydrotestosterone.
The other actions -
Antibacterial
Antiprotozoan
Antiviral
Hypolipemic
Hypoglycemic
Anticoagulant
Antioxidant
Antitumour
Anticarcinogenic
www.ias.ac.in/currsci/jul102004/44.pdf
» 500 mg. of curcumin (concentrate)
» 100 mg. of resveratrol
» 60 mg. of tocotrienols (high absorption)
»
» For me, this means only three capsules per day (though the bottles may
» recommend twice as much).
» a…way of functionally decreasing all your androgens in your system?
All? Not all.
» Popping pills to affect ARs in some way . . . it all sounds kind of like
» just a different way to get the effects of oral Spiro to me. No thanks.
Oral Spiro? Heaven forbid!
No thanks? That just means more wine, curry, and fruit for the rest of us!
I am no longer experiencing any dandruff.
The Tragedy of Tumeric For Hairloss
From: The New Straits Times
04-28-08
TUMERIC is a very important in Ayurvedic medicine, the 5,000- year-old Indian healing system. It has been used through the ages as an "herbal aspirin" and "herbal steroid" to relieve swelling and pain.
The Materia Medica, a standard Ayurdevic reference, cites dozens of conditions in which turmeric can be helpful as an add on therapy for many ailments, including tissue injury and pain.
According to Mark Blumenthal, executive director of the American Botanical Council based in Austin, Texas, "The high degree of reverence for turmeric is evidenced by the fact that it is used in nearly all Asian cultures".
Turmeric is a very powerful, anti-inflammatory agent. It would be useful for any condition that is accompanied by pain and swelling. Taken orally, turmeric inhibits the response of the body to inflammation and pain causing agents both directly and indirectly.
It stimulates the production of natural steroid (corticosteroids) from the adrenal glands. They also make the cortisone receptor sites on cells more sensitive and prevent the breakdown of cortisol (the body's own natural steroid). This has a powerful effect on reducing swelling and reducing pain.
In fact, curcumin (one of the active molecules of turmeric) has been found to be every bit as effective as the pharmaceutical drugs cortisone, indometacin and phenylbutazone in clinical trials.
The anti-inflammatory effects are comparable in effectiveness to pharmaceutical drugs (such as phenylbutazone and indomethacin) but without the serious side effects.
Turmeric extracts prevented the synthesis of inflammatory chemicals in the body in a clinical trial of patients with rheumatoid arthritis.
Turmeric lowered concentration of the hormone-like substances responsible for the inflammation in arthritis and lessened the severity of morning stiffness, joint pain, and walking difficulty.
Despite all this good news, there is one very big tragedy with turmeric. It is poorly absorbed. In fact, less than one per cent of the oral dose actually gets into the blood.
"Nearly, all the effect of turmeric are on the walls of the intestines as hardly anything gets absorbed," said Dr Gulam Nabi Qazi, director of the Indian Institute of Integrative Medicine.
However, new extraction technology and the use of an oligosaccharide molecule now makes it possible for the turmeric extracts to be absorbed by up to 1,000 times.
The new technology increases solubility. This makes it possible to obtain fast action on inflammatory symptoms by guaranteeing bio equivalence of 1,200 mg/day (therapeutic daily dosage).
The new high blood levels of turmeric represents an advance over steroids, analgesics (paracetamol), non-steroidal anti-inflammatory drugs and painful Intra articular injection with steroids, and hyaluronic acids.
Sufficient dose levels can now be introduced into the blood. This allows for high level of composition in curcuminoids - vital to the anti-inflammatory effects. The new turmeric extract has an activity comparable to non-steroidal anti-inflammatory drugs without any side effects.
More importantly, it helps prevent cartilage degeneration - the cost of long term pain, disability and disfigurement in arthritis.
The Australian Therapeutic Goods Administration allows a claim of "may be used for the treatment of acute and chronic arthritic pain".
Professor Yves Henrotin, who is the Director of the Bone and Cartilage Research Unit at the University of Liege, Belgium sees this as a big new possibility, especially since there has been no real new innovation in the non-steroidal anti-inflammatory drug market globally.
The professor, who is in Malaysia now to meet opinion leaders and deliver a series of public lectures, said the turmeric extract delivers complete inflammatory mediators inhibition in the following ways and comparable to the most sophisticated pharmaceutical drugs:
Editor’s Note:
Curcumin has such potent therapeutic properties that even the miniscule absorption of whole tumeric, such as that used in the patented oral hair loss treatment, “Capsures” (Resveratrol Curcumin combination) was found to have hair growth promoting effects. This hair growth promoting effect, while not definitively known, is likely due to the release of Substance P.
Most commercially available preparations of curcumin have very poor bioavailability, impairing their ability to confer hair growth properties. Scientists have recently discovered a novel curcumin preparation with exceptional bioavailability. In a human study, this advanced curcumin preparation—termed BCM-95®—delivered up to seven times more curcumin to the bloodstream than a standard curcumin product. This increased bioavailability should greatly enhance curcumin’s benefits.
At MPB Research we utilize BCM-95, called “Super Bio-Curcumin” mentioned above , which results in higher and longer sustained blood levels. In fact each 400 mg capsule contains the equivilant of 2772 mg of commercially available 95% Curcumin extracts.
Capsures, the patented Resveratrol/Curcumin combo from Italy uses 82.4mg of a 95% Extract of Curcumin per capsule, 4 times a day, for a total of 350mg. Super Bio-Curcumin gives you their equivilant of 2772mg , which gives more benefits and is far more cost effective.I tried to order some of it, but it costs $20 to ship to Thailand. Maybe I’ll wait until I’m in the states again.
Perry, I am using Jarrow’s TOCO-SORB. It’s very good.
oh cool, I’ll have to check out the shipping on that company. Thanks.
» oh cool, I’ll have to check out the shipping on that company. Thanks.
Yes, please do. And iHerb.com sells TOCO-SORB at almost half the price as my local nutrition store.
Hi Guys
I have just ordered TOCO-8, I have a receeding hairline and I am desperate to stop it going any further, I have tried fin but got sides after just two weeks so I have decided to quit it. I was also using rogain foam but that only seemed to make my hairline worse. I am looking for a natural alternative. Judging by the above comments on curcumin and reservatol would this be the right product to take along with TOCO-8?
http://www.tattvasherbs.com/turmericplus.htm
Thanks
» Hi Guys
»
» I have just ordered TOCO-8, I have a receeding hairline and I am desperate
» to stop it going any further, I have tried fin but got sides after just two
» weeks so I have decided to quit it. I was also using rogain foam but that
» only seemed to make my hairline worse. I am looking for a natural
» alternative. Judging by the above comments on curcumin and reservatol would
» this be the right product to take along with TOCO-8?
»
» Sitemap
»
» Thanks
Helpme23, that’s a good find. It’s cheaper than Life Extension’s:
http://www.iherb.com/ProductDetails.aspx?c=1&pid=1991456822181762381
I am using Jarrow’s now, but I may switch to one these.
"Curcumin is the main primary component of turmeric, so it’s also sold under that name.
[The] ConsumerLab which is an independent lab that tests supplements [has] done testing on various brands of turmeric/curcumin supplements and discovered that some brands weren’t delivering what they promised. Some didn’t have the amount of curcuminoids they claimed and others were contaminated with lead.
Things to look for when you buy turmeric supplements:
Species of turmeric (look for Curcuma longa, although the use of the accepted common name “turmeric” is sufficient to denote this species)
Part of the plant used (should be “root” or “rhizome”)
Form of turmeric used (e.g., root/rhizome powder or extract)
Amount of turmeric per pill or dose in grams (g) or milligrams (mg) [1 gram = 1,000 milligrams]
These are things that are required on the labels by the FDA."
First Major Product Review of Potential “Life-Extending” Ingredient
(HealthNewsDigest.com) - WHITE PLAINS, NEW YORK — ConsumerLab.com reported today that its tests of supplements containing resveratrol – a compound promoted as “life-extending” – revealed two products providing only 27% and 58% of their listed amounts of resveratrol. A third product, which boasted several hundred milligrams of a “red wine grape complex,” contained only two milligrams of resveratrol. Several other products contained their listed amounts of resveratrol, although daily doses ranged from just 1 milligram to as much as 1,000 milligrams. None of the products were contaminated with lead or cadmium, which can occur in plant-based supplements.
Resveratrol products have proliferated following reports late last year of life-extending and athletic endurance-enhancing activity in animals. Laboratory research has also shown antioxidant, anti-inflammatory, anticancer, and other effects. Human studies of its effectiveness have not been reported, but at least one researcher in the field, Dr. David Sinclair at Harvard Medical School, is noted as taking resveratrol personally at a dose of approximately 350 mg per day.
Along with widely ranging dosage suggestions on products, ConsumerLab.com found similar variation in the cost of resveratrol. To obtain 100 mg of resveratrol from any product, the cost ranged from as little as $0.20 to as much as $45.57 – more than a 22,000% difference. Using the lowest cost product that passed ConsumerLab.com’s testing, the daily cost for a dose of 300 to 400 mg would be $0.60 to $0.80 per day. To get that dose from any of the products with single digit milligram amounts of resveratrol would be impractical – requiring hundreds of pills per day and costing as much as $159. For some products, the price difference may reflect the cost of additional ingredients.
“I am not surprised that some resveratrol supplements failed to meet their ingredient claims,” said Tod Cooperman, MD, President of ConsumerLab.com which has tested more than two thousand supplements since 1999. “When an ingredient quickly becomes popular as a supplement, we often see products rush to market that range widely in quality, dose, and price. There is still much to learn about resveratrol. At least now those who choose to use it can find out which products contain what they claim and which do not.”
The ConsumerLab.com report is available at http://www.consumerlab.com/results/resvera...ol_red_wine.asp. It includes findings for nine products selected by ConsumerLab.com as well as four that passed ConsumerLab.com’s Voluntary Certification Program. Brands included are French Parad’ox (Arkopharma), Purevinol (Pure Prescriptions), Resvert (Young Again), Resvera-Gold (Douglas Laboratories), Revatrol (Renaissance Health), Transmax (Biotivia), Vinotrol (NeXtten), and Zyflamend (New Chapter), as well as products from Country Life, Jarrow Formulas, Life Extension, Longevinex, and Swanson. The report also provides information regarding the dosage and possible side-effects.
"[ConsumerLab] tested 13 brands (not including NOW, RevGenetics, among others).
Found most complied with stated resveratrol content (and most of this ~98%, was trans-resveratrol, apparently), including Jarrow, Biotiva Transmax, Swanson.
Life Extension Foundation 20 mg tabs and Young Again tabs failed- [as they contained] much less [resveratrol than is stated on the their respective bottles]."
“Resveratrol exists in both trans-and cis-forms. However, published researched suggests that only the trans-form has considerable biological activity.”
"As seen on TV with Barbara Walters! Every capsule of [this] physician strength Resveratrol is equivalent to 35 glasses of red wine, plus healthy, life enhancing red wine polyphenols that will support:
Powerful cardiovascular benefits*
Antioxidant protection against harmful free-radicals*
Longevity, wellness & anti-aging*
No Alcohol - Healthy Vegetarian Capsules!
SOME “RED WINE” SUPPLEMENTS DELIVER LESS RESVERATROL THAN EXPECTED. PureVinol-25 is tested by Consumer Lab as being among
the most potent on the market. Don’t be fooled by brands of Resveratrol that claim that they are the best or most potent available. What really matters and what you need to know before you buy is that the Resveratrol supplement in question should clearly state the specific amount of trans-resveratrol.
PureVinol-25™ Resveratrol was tested and given the thumbs up by ConsumerLab.com, the leading provider of independent test results and information to help consumers and healthcare professionals evaluate health, wellness, and nutrition products."
According to GiGi’s website, antiagingnutritionnews.com:
“I’ve recently joined Consumer Lab which is an independent lab that tests supplements. They’ve done testing on various brands of turmeric/curcumin supplements and discovered that some brands weren’t delivering what they promised. Some didn’t have the amount of curcuminoids they claimed and others were contaminated with lead…Obviously, Consumer Lab did not test ALL turmeric supplements, but one brand that DID pass their testing was: New Chapter’s TumericForce.”
New Chapter Turmericforce
Dual Extracted Full-Spectrum Turmeric
Researched for maintaining healthy inflammation response*
Maintains healthy cardiovascular and liver function*
World’s most important protective botanical
New Chapter has been in love with turmeric for decades. We grow it on our Biodynamic? farm in Costa Rica, which is nestled in the volcanic mountains adjoining the Children’s Eternal Rainforest. Turmeric has long been revered as the foundation of an herbal program for health. In India’s system of Ayurvedic medicine, turmeric has been recognized for thousands of years as a key balancing and detoxifying herb. In Indonesia’s traditional medical system known as Jamu, turmeric is considered the “Queen” of all herbs, and is the featured daily herb for tens of millions of Indonesians. In Japan and China, people embrace turmeric for its powerful yet safe liver detoxification, and there are societies in Japan where turmeric juice is consumed daily. In the Western medical and herbal traditions, turmeric is considered by many leading scholars to be the most important healing herb on earth.
We at New Chapter agree that turmeric is the world’s most important healing herb, and we are proud that Turmericforce is the world’s first and only supercritical full-spectrum turmeric extract. We take our full-spectrum turmeric, and without chemical solvents or heat stress, concentrate radiant turmeric oils as much as 200:1. This is combined with a full-spectrum hydroethanolic extract that potency assures it for at least 11% of the full curcuminoid fractions. This is not a mere isolate of standardized turmeric, offering just one or more of the curcuminoids. This is turmeric’s full healing glory.*
New Chapter’s Supercritical Herbal Extracts
“Supercritical” means Super Purity, Super Potency, Broad Spectrum, and No Chemical Solvents. We take nature’s finest herbs and then extract and highly concentrate (as high as 250 to 1) their precious ingredients. We do not isolate out single ingredients or spike our extacts with synthesized additives. We deliver the wisdom of nature, with the complexity and organic nuances of the natural herb preserved for you. In fact, the supercritical process is the gentlest way to extract these delicate plant compounds in a manner to optimally preserve their potency and stability. And when you take
New Chapter’s supercritical extracts, neither you, nor the environment, have to contend with chemical solvents.
*Certified Biodynamic by Demeter Association, P.O. Box1390, Philomath, OR 97370
The great thing about TumericForce is that you only need to take one capsule per day.
WHITE PLAINS, NEW YORK — FEBRUARY 6, 2008 — Turmeric supplements have become popular in recent years but ConsumerLab.com warned today that some products contain high amounts of lead. Recent tests found a popular brand to contain 18.7 mcg of lead in a daily serving — the highest amount ever reported by ConsumerLab.com. A daily serving of another brand was contaminated with 8.3 mcg of lead. These amounts are well above those to which people are normally exposed and should be avoided. The State of California, for example, requires supplements with more than 0.5 mcg of lead to carry a warning label. Lead-contaminated products should be particularly avoided by children — who can experience lead toxicity with only 6 mcg per day — and pregnant women.
Interest in turmeric’s anti-inflammatory and anti-oxidant activities has propelled sales from just $8 million in 2002 to $32 million in 2006 according to Nutrition Business Journal. Sales growth last year continued to be strong according to SPINSscan. Recent research has focused on compounds in turmeric called curcuminoids and, more specifically, curcumin, which gives turmeric its yellow color. Two products failed to pass ConsumerLab.com’s tests because they provided only 11.5% and 49.5%, respectively, of expected curcuminoids. A fifth product did not specify the part of the plant used — a FDA labeling requirement. ConsumerLab.com purchased the supplements from stores, catalogues, and online retailers. All deficiencies were confirmed in a second independent laboratory.
“Consumers should be very careful to select a turmeric product that is not contaminated and provides the expected amount of active compounds,” said Tod Cooperman, MD, President of ConsumerLab.com.
» Just posted by “jasonlv” on another BB.
»
» Its a Vitamin E complex containing ALL 8 forms of Vitamin E in a powder
» form to add to water etc.
»
» It has received a US Patent for hair growth in 2007.
»
» US Patent # 7,211,274
» Hair growth formulation
» US Patent Issued on May 1, 2007
»
» In this Patent they claim their study showed an “increase in the number of
» hairs is 42.4 (±40.9%) over 5 months.”
»
» Its only $29 for a 60 day supply.
»
» TOCO-8 website:
» http://www.primordialperformance.com/toco.cfm
Hey Col, does it say that is from how many test subjects? Sorry, too lazy to go through the whole patent.
If this is from a large population, then I may consider trying.
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