Apologize for adding a new post to the previous, but I hope a focus on the findings and research – rather than flaming – will contribute positively to the discussion on this forum.
It appears that minor structural variants on Ramatroban result in an entire blockage of PGD2. This is “insurmountable” according to the authors. The most “insurmountable” compound is TM-30089. It functionally shuts down PGD2. Moreover, this compound is highly selective (thus not affecting other pathways) and is entirely soluble in water.
You can purchase TM-30089 here: