Silymarin (Milk Thistle) and epidermal growth factor

Stem cell; cell based hair therapy
1

A guy at HLT pointed out that silymarin (about 4-6% of milk thistle, but standardized to be 60% or so of Milk Thistle Extract) inhibits the epidermal growth factor receptor.

Ive looked around and could not find where this substnace inhibits the wnt pathway like the other natural egf-inhibitors (like green tea, apple polyphenols, quercetin, et cetera) do.

Could this be a “natural” that we could use instead of getfitinib? Interesting…

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» A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells - PubMed
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» A guy at HLT pointed out that silymarin (about 4-6% of milk thistle, but
» standardized to be 60% or so of Milk Thistle Extract) inhibits the
» epidermal growth factor receptor.
»
» Ive looked around and could not find where this substnace inhibits the wnt
» pathway like the other natural egf-inhibitors (like green tea, apple
» polyphenols, quercetin, et cetera) do.
»
»
» Could this be a “natural” that we could use instead of getfitinib?
» Interesting…

ok have to dig the stuff out from bellow my bed :slight_smile: