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Retinol Grows Hair in Study


#1

How I Accidentally Grew Hair on My Left Temple with Retinol – Experiment Conclusion

This post is the rather surprising conclusion of my topical retinol experiment.

For the past six months, I’ve used retinol, a form of vitamin A, on the left side of my face. The idea was to see whether it improves fine wrinkles and increases collagen production like at least one study suggests.

I have to admit I haven’t seen much in terms of skin quality during these six months. I don’t really have wrinkles at this age, but the fine lines on my forehead and the small crow’s feet next to my eyes are still there.

I don’t doubt the quality of the product, however. Applying the cream on my face gives a slight tinge, and afterwards there is a small but notable peeling effect. This peeling effect is behind the effectiveness of stronger forms of vitamin A, like tretinoin. Retinol is not supposed to cause peeling, but at least the 2% cream I used seemed to do so.

The surprise is that I have grown a few new hairs on my left temple. Even though I have experimented with and reported on various substances that are supposed to grow hair, this experiment was not supposed to be about growing hair. It happened by accident.

I’m pretty sure my hairline has always been where it is now, and no hair has ever grown where these new hairs are suddenly sprouting up. I’m not sure yet whether they’re vellus hairs or terminal hairs, but it seems they’re still growing.

I attempted to capture the whole thing with a camera. The result is not that great, but you can see the areas where the 3-4 new hairs are growing from circled with red.


On the right temple where no retinol was applied, no new hair is growing, so I think it’s safe to conclude that the hair growth effect is due to the retinol cream. If you’ve read the blog before, you know that this is not my usual conclusion (for examples, see the conclusions to my MSM experiment and biotin experiment).

As you can see, it’s very modest: only a couple of new hairs are growing and you kind of have to zoom in to even see it. Still, I find the result interesting, since it proves that retinol is absorbed and does something to the skin. It’s effect on wrinkles may be too small to notice, but it’s effect on hair growth is visible.

Especially strange is that, as far as I know, this is not a part of the skin where hair used to grow and is now growing again, but a part of the skin where hair has never grown.

If you’re bald, I doubt retinol cream alone will grow you a new set of hair. Nonetheless, I think these results warrant further studies on how different forms of vitamin A affect hair growth. I’m probably going to give tretinoin a go next to see whether the stronger stuff has a stronger effect.

I would like to see these results replicated in other people, so if you’ve tried retinol or tretinoin, do drop a comment and tell about your experience!


#2

» How I Accidentally Grew Hair on My Left Temple with Retinol – Experiment
» Conclusion

»
» This post is the rather surprising conclusion of my topical retinol
» experiment.
»
» For the past six months, I’ve used retinol, a form of vitamin A, on the
» left side of my face. The idea was to see whether it improves fine wrinkles
» and increases collagen production like at least one study suggests.
»
» I have to admit I haven’t seen much in terms of skin quality during these
» six months. I don’t really have wrinkles at this age, but the fine lines on
» my forehead and the small crow’s feet next to my eyes are still there.
»
» I don’t doubt the quality of the product, however. Applying the cream on
» my face gives a slight tinge, and afterwards there is a small but notable
» peeling effect. This peeling effect is behind the effectiveness of stronger
» forms of vitamin A, like tretinoin. Retinol is not supposed to cause
» peeling, but at least the 2% cream I used seemed to do so.
»
» The surprise is that I have grown a few new hairs on my left temple. Even
» though I have experimented with and reported on various substances that are
» supposed to grow hair, this experiment was not supposed to be about growing
» hair. It happened by accident.
»
» I’m pretty sure my hairline has always been where it is now, and no hair
» has ever grown where these new hairs are suddenly sprouting up. I’m not
» sure yet whether they’re vellus hairs or terminal hairs, but it seems
» they’re still growing.
»
» I attempted to capture the whole thing with a camera. The result is not
» that great, but you can see the areas where the 3-4 new hairs are growing
» from circled with red.
»
»
»
»
» On the right temple where no retinol was applied, no new hair is growing,
» so I think it’s safe to conclude that the hair growth effect is due to the
» retinol cream. If you’ve read the blog before, you know that this is not my
» usual conclusion (for examples, see the conclusions to my MSM experiment
» and biotin experiment).
»
» As you can see, it’s very modest: only a couple of new hairs are growing
» and you kind of have to zoom in to even see it. Still, I find the result
» interesting, since it proves that retinol is absorbed and does something to
» the skin. It’s effect on wrinkles may be too small to notice, but it’s
» effect on hair growth is visible.
»
» Especially strange is that, as far as I know, this is not a part of the
» skin where hair used to grow and is now growing again, but a part of the
» skin where hair has never grown.
»
» If you’re bald, I doubt retinol cream alone will grow you a new set of
» hair. Nonetheless, I think these results warrant further studies on how
» different forms of vitamin A affect hair growth. I’m probably going to give
» tretinoin a go next to see whether the stronger stuff has a stronger
» effect.
»
» I would like to see these results replicated in other people, so if you’ve
» tried retinol or tretinoin, do drop a comment and tell about your
» experience!

It is not unusual to have hairs come and go well below your hairline. Copper peptides should work better than retinol in theory.


#3

» » How I Accidentally Grew Hair on My Left Temple with Retinol –
» Experiment
» » Conclusion

» »
» » This post is the rather surprising conclusion of my topical retinol
» » experiment.
» »
» » For the past six months, I’ve used retinol, a form of vitamin A, on the
» » left side of my face. The idea was to see whether it improves fine
» wrinkles
» » and increases collagen production like at least one study suggests.
» »
» » I have to admit I haven’t seen much in terms of skin quality during
» these
» » six months. I don’t really have wrinkles at this age, but the fine lines
» on
» » my forehead and the small crow’s feet next to my eyes are still there.
» »
» » I don’t doubt the quality of the product, however. Applying the cream
» on
» » my face gives a slight tinge, and afterwards there is a small but
» notable
» » peeling effect. This peeling effect is behind the effectiveness of
» stronger
» » forms of vitamin A, like tretinoin. Retinol is not supposed to cause
» » peeling, but at least the 2% cream I used seemed to do so.
» »
» » The surprise is that I have grown a few new hairs on my left temple.
» Even
» » though I have experimented with and reported on various substances that
» are
» » supposed to grow hair, this experiment was not supposed to be about
» growing
» » hair. It happened by accident.
» »
» » I’m pretty sure my hairline has always been where it is now, and no
» hair
» » has ever grown where these new hairs are suddenly sprouting up. I’m not
» » sure yet whether they’re vellus hairs or terminal hairs, but it seems
» » they’re still growing.
» »
» » I attempted to capture the whole thing with a camera. The result is not
» » that great, but you can see the areas where the 3-4 new hairs are
» growing
» » from circled with red.
» »
» »
» »
» »
» » On the right temple where no retinol was applied, no new hair is
» growing,
» » so I think it’s safe to conclude that the hair growth effect is due to
» the
» » retinol cream. If you’ve read the blog before, you know that this is not
» my
» » usual conclusion (for examples, see the conclusions to my MSM
» experiment
» » and biotin experiment).
» »
» » As you can see, it’s very modest: only a couple of new hairs are
» growing
» » and you kind of have to zoom in to even see it. Still, I find the
» result
» » interesting, since it proves that retinol is absorbed and does something
» to
» » the skin. It’s effect on wrinkles may be too small to notice, but it’s
» » effect on hair growth is visible.
» »
» » Especially strange is that, as far as I know, this is not a part of the
» » skin where hair used to grow and is now growing again, but a part of
» the
» » skin where hair has never grown.
» »
» » If you’re bald, I doubt retinol cream alone will grow you a new set of
» » hair. Nonetheless, I think these results warrant further studies on how
» » different forms of vitamin A affect hair growth. I’m probably going to
» give
» » tretinoin a go next to see whether the stronger stuff has a stronger
» » effect.
» »
» » I would like to see these results replicated in other people, so if
» you’ve
» » tried retinol or tretinoin, do drop a comment and tell about your
» » experience!
»
» It is not unusual to have hairs come and go well below your hairline.
» Copper peptides should work better than retinol in theory.

Fat Synthesizing Enzyme Is Key To Healthy Skin And Hair

ScienceDaily (Feb. 17, 2009) — Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair.

The enzyme is acyl CoA:diacylglycerol acyltransferase 1 or DGAT1. Mice that lack DGAT1 have many interesting characteristics. For example, they are lean, resistant to diet-induced obesity, are more sensitive to insulin and leptin, and have abnormalities in mammary gland development and skin.

When Gladstone researchers in the laboratory of Robert V. Farese, Jr. used genetic engineering to delete the enzyme in mice, they found that lack of DGAT1 caused levels of retinoic acid (RA) to be greatly increased in skin and resulted in the loss of hair. Their findings were reported in The Journal of Biological Chemistry.

“For some time, we have been studying the enzymes that make triglycerides,” said Robert V. Farese, Jr., senior investigator and senior author on the study. “We found that one of these enzymes is a major regulator of retinoic acid actions in the skin.”

RA, which comes from vitamin A (retinol) has been used to treat skin disorders, such as acne and psoriasis, and certain cancers, but it is fairly toxic and must be carefully controlled.

In mice without DGAT1, the skin was very sensitive to retinol. The loss of DGAT1 also caused alopecia, or hair loss. Both of these effects could be prevented by depriving the mice of a source of retinol in their diet. It turns out that DGAT1 can convert retinol to a relatively inert storage form. Without DGAT1, this ability is lost, and any excess retinol in the skin can be converted to RA.

“Our results show that DGAT1 is an important component for controlling retinoic acid levels in the skin of mice,” said Michelle Shih, the lead author on the study. “These findings may have implications for the treatment of human skin or hair disorders.”

Maureen A. Kane, Ping Zhou, C.L. Eric Yen, Ryan S. Streeper, Joseph L. Napoli, & Robert V. Farese Jr. also contributed to the research. Funding was provided by NIH grants DK-056084 to R.F. and DK36870 to JLN, and by an extramural research facilities grant from the National Center for Research Resources (C06 RR018928), and by the J. David Gladstone Institutes.


#4

» For the past six months, I’ve used retinol, a form of vitamin A, on the
» left side of my face. The idea was to see whether it improves fine wrinkles
» and increases collagen production like at least one study suggests.

I think it’s a bit misleading to say that retinol is “a form of vitamin A”. Retinol is vitamin A!

As for the part about improving fine wrinkles – are you confusing retinol (vitamin A) with Retin-A? :slight_smile:


#5

BRYAN, I HAVEN’T SHARED THIS WITH ANYONE, BUT HOW DO YOU EXPLAIN THIS…

I HAVE STOPPED USING MINOXIDIL FOR 3 WEEKS NOW (give or take) AND USE DUT ABOUT 1 - TIMES A WEEK FOR THE PAST 60 DAYS. MY CROWN IS STILL FILLING IN.

» » For the past six months, I’ve used retinol, a form of vitamin A, on the
» » left side of my face. The idea was to see whether it improves fine
» wrinkles
» » and increases collagen production like at least one study suggests.
»
» I think it’s a bit misleading to say that retinol is “a form of vitamin
» A”. Retinol is vitamin A!
»
» As for the part about improving fine wrinkles – are you confusing retinol
» (vitamin A) with Retin-A? :slight_smile:


#6

» BRYAN, I HAVEN’T SHARED THIS WITH ANYONE, BUT HOW DO YOU EXPLAIN THIS…
»
» I HAVE STOPPED USING MINOXIDIL FOR 3 WEEKS NOW (give or take) AND USE DUT
» ABOUT 1 - TIMES A WEEK FOR THE PAST 60 DAYS. MY CROWN IS STILL FILLING
» IN.

Beats me what’s going on there…