Questions about Aderans Phase 2

baldIsMe · January 14, 2010, 6:23am

I am wondering a few things about Aderans:

When is the current trial supposed to be completed? I remember hearing ‘end of 2009’ but I think this was said by some forum junkie and not the company itself.
I think ARI’s chance of success is remote. There are still too many problems with getting HM to work. Plus the company’s credibility has been dimished by Dr. W. What are your opinions?

cal · January 14, 2010, 8:54pm

I don’t know which major problems with HM that you refer to. Dermal Papillae cell methods of HM have not shown any problems with hair (the color, characteristics, growth direction, etc) than plagued the cloning-based HM projects. DP methods seem liable to either grow the hairs right or not at all.

Aderans has to get the cells multiplied right and get them re-inserted into the damaged follicles correctly. If they can do that, then IMHO the core science of their project should work.

krapok · January 15, 2010, 12:25pm

Someone who lives close them and speaks English fluently should give them a call and ask how they are doing. We know that they are already on phase 2 several months (about 9 months) and would be great if they can give answers to some simple questions (they probably don’t answer to specific questions) for example:

how successful their phase 2 studies have been until today
do they see signifficant hair growth most of their patients until today
if they have had successful studies until today then what they think how much time it would take to bring this cure to market.
We know that they removed from their website words “cure would be available by the end of the decade”. Does it mean that their studies isn’t so successful and they have no idea how many years it may actually take.
when they gonna finish phase 2 studies? from some articles in internet we can read that studies should be over by the end of 2009. Is it correct and have you finised them by now?
when do you publish your phase 2 results as a press release?

asking doesn’t cost anything and would be great to hear something about their studies

fckhrls · January 15, 2010, 8:49pm

» Someone who lives close them and speaks English fluently should give them a
» call and ask how they are doing. We know that they are already on phase 2
» several months (about 9 months) and would be great if they can give answers
» to some simple questions (they probably don’t answer to specific questions)
» for example:
»
» - how successful their phase 2 studies have been until today
» - do they see signifficant hair growth most of their patients until today
» - if they have had successful studies until today then what they think how
» much time it would take to bring this cure to market.
» - We know that they removed from their website words “cure would be
» available by the end of the decade”. Does it mean that their studies isn’t
» so successful and they have no idea how many years it may actually take.
» - when they gonna finish phase 2 studies? from some articles in internet
» we can read that studies should be over by the end of 2009. Is it correct
» and have you finised them by now?
» - when do you publish your phase 2 results as a press release?
»
» asking doesn’t cost anything and would be great to hear something about
» their studies

The only thing they might answer is when they anticipate publishing the Stage II trials. Their number is: 1-215-382-7705

hairman2 · January 15, 2010, 8:53pm

» » Someone who lives close them and speaks English fluently should give them
» a
» » call and ask how they are doing. We know that they are already on phase
» 2
» » several months (about 9 months) and would be great if they can give
» answers
» » to some simple questions (they probably don’t answer to specific
» questions)
» » for example:
» »
» » - how successful their phase 2 studies have been until today
» » - do they see signifficant hair growth most of their patients until
» today
» » - if they have had successful studies until today then what they think
» how
» » much time it would take to bring this cure to market.
» » - We know that they removed from their website words “cure would be
» » available by the end of the decade”. Does it mean that their studies
» isn’t
» » so successful and they have no idea how many years it may actually
» take.
» » - when they gonna finish phase 2 studies? from some articles in
» internet
» » we can read that studies should be over by the end of 2009. Is it
» correct
» » and have you finised them by now?
» » - when do you publish your phase 2 results as a press release?
» »
» » asking doesn’t cost anything and would be great to hear something about
» » their studies
»
» The only thing they might answer is when they anticipate publishing the
» Stage II trials. Their number is: 1-215-382-7705

and i wouldn’t even be too sure on that

Spanish_Dude · January 15, 2010, 11:14pm

Does anyone know if they are still advertising the trials for recruitment of trialists in those free newspapers?

roger_that · January 18, 2010, 11:48pm

» Does anyone know if they are still advertising the trials for recruitment
» of trialists in those free newspapers?

They were still advertising in the “Express” free newspaper Washington, DC up until about 2 - 2.5 months ago. I emailed them asking to be part of the trials about 3 weeks ago, and about 4 days ago I got an email back saying words to the effect of “We are not currently conducting trials in your area…”

Then WHY were they advertising in the DC area??? No explanation of that was given.

Spanish_Dude · January 19, 2010, 1:54am

» » Does anyone know if they are still advertising the trials for
» recruitment
» » of trialists in those free newspapers?
»
» They were still advertising in the “Express” free newspaper Washington, DC
» up until about 2 - 2.5 months ago. I emailed them asking to be part of
» the trials about 3 weeks ago, and about 4 days ago I got an email back
» saying words to the effect of “We are not currently conducting trials in
» your area…”
»
» Then WHY were they advertising in the DC area??? No explanation of that
» was given.

mmmh, maybe they meant “we are not recruiting trialists in your area anymore?”
If the adv was published 2-2.5 months ago, and you emailed them 3 weeks ago, it is possible that they already finished recruitment by the time you emailed them.

It is clear that they are indeed running trials in DC.
From ARI’s website:

roger_that · January 19, 2010, 2:25am

I live in the immediate DC area – about 7 miles from Washington. I gave them my address. Their email didn’t even say “not conducting trials in your area anymore.” It simply said they are not conducting trials in my area. It was a “form” email – not personalized.

Spanish Dude – maybe they were only recruiting in all these cities (like DC), but doing the trials only in a couple of cities like Philadelphia and Atlanta, where ARI has labs…? After all it’s only about 2.5 hours from here to Philadelphia. And maybe now they have enough trialists?

roger_that · January 19, 2010, 2:46am

Here is the Aderans email:

We are not doing any clinical trials in your area at this time.
We are recruiting for our Phase 2 clinical research study in the US. We must at least await the results of the study before we can provide an estimate of general availability with any assurance. We understand the interest and desire to have a cell-product such as ours available for treatment of hair loss, and are working diligently to meet the hopes of people such as you.
We suggest you monitor our website for updates, www.aderansresearch.com

Thank you for your interest,

Info Desk
Aderans Research
advancing hair regeneration™

Spanish_Dude · January 19, 2010, 12:35pm

My idea is that Bosley has clinics in all these cities. The trialist go to the Bosley clinic in his/her city, they take a biopsy (donor cells), and they send the biopsy to the ARI labs (Philadelphia or Atlanta or wherever). The cultured cells are sent back to the Bosley clinic for injection. And the followups also in the Bosley clinic.
This was my idea, but of course it could be that, as you suggest, the trialists had to travel to the labs for biopsy and for injection, and followups were done in the Bosley clinic. But in any case, if they are recruiting in DC, this means that there is a trial going on in DC, regardless of where do they take biopsies and make injectios. And the email should have specified.

The email doesn’t make sense. They answered that “we are not conducting trials in your area”, but even if the trialists had to travel to other city, this doesn’t warrant that answer.
It is irrelevant if they are conducting trials or not in your city, the proper subject is if they are recruiting or not, and the advertisement said that they were recruiting in DC. Well, in fact the advertisement said that they were “conducting a study in DC”.

so yes, you are right, the email doesn’t make sense. at all.

Maybe the trial was cancelled in DC???

» I live in the immediate DC area – about 7 miles from Washington. I gave
» them my address. Their email didn’t even say “not conducting trials in
» your area anymore.” It simply said they are not conducting trials in my
» area. It was a “form” email – not personalized.
»
» Spanish Dude – maybe they were only recruiting in all these cities (like
» DC), but doing the trials only in a couple of cities like Philadelphia and
» Atlanta, where ARI has labs…? After all it’s only about 2.5 hours from
» here to Philadelphia. And maybe now they have enough trialists?