Obesity & low-grade inflammation among young men with early-onset alopecia

Obesity and low-grade inflammation among young Finnish men with early-onset alopecia.

Dermatology. 2007;214(2):125-9

Previous investigations have revealed an association of androgenetic alopecia (AGA), especially in younger subjects with severe early-onset AGA, with ischemic heart disease.

To examine the possible association between early-onset alopecia and low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) that has been recommended for the assessment of the cardiovascular disease (CVD) risk.

The study population consisted of young men (n = 727, aged 25-34 years) participating in a national survey. The grade of alopecia was assessed by a trained nurse using the Norwood/Hamilton Classification Scale.

Men with moderate to extensive alopecia (17%) had a higher body mass index and larger waist, upper arm, hip and waist circumference than those with little to no alopecia (p < 0.05), and statistically insignificant differences were seen in the waist-to-hip circumference ratio (WHR), diastolic blood pressure and hs-CRP. With increasing hs-CRP, the mean WHR increased, but only among men with moderate to extensive alopecia (p = 0.043).

Our findings show a relation between moderate to extensive alopecia and low-grade inflammation–a predictor of a future CVD–especially combined with central obesity, among men younger than 35 years.

could be the guys with thinning hair get depressed, get not as many dates, and start sitting home and eating and getting chubby

unless they are certain that the guys started thinning AFTER they got chubby, the study is useless