Recently in Germany conducted studies on Latanoprost.
google translation
In the current study, a 0.1% solution for 24 weeks was used by the subjects. The study was single center, double-blind, randomized created. Each subject covered a small area of scalp with the latanoprost solution, a different, balanced on the other side of the head with a placebo solution. Study participants were 23 to 35 years old, with dark blond to light brown hair and a recently developed androgenetic alopecia Hamilton grade II to III. Determined, the rate of hair growth, hair density, telogen to anagen and diameter ratio using the Trichoscans. Übersichtphotografien were fabricated, evaluated the tolerability and hair pigmentation.
Results:
After 24 weeks was demonstrated in the areas treated with latanoprost, a significant increase in hair density compared to baseline (starting at 8 week, 24 weeks +22%) and compared with the placebo-treated areas.
Evidence of a non-significant decrease and increase in the Anagenhaarrate Telogenhaarrate in both treatment groups.
Appearance of redness in 5 patients in the treated areas with latanoprost.
Assessment:
Latanoprost is to increase the ability of young men with androgenetic alopecia, in particular, the hair counts. Prostaglandin analogs may thus with, which is latanoprost, a new group of drugs for the treatment of androgenetic alopecia (AGA) are available. But it is unclear whether the therapy in older men (it is assumed) and also in more advanced stages of AGA is effective. Equally unclear is whether latanoprost is similarly effective in other areas of the scalp. At 1/3 of the patients there is redness of the scalp in the area treated with latanoprost come. Prior to application outside of a precise dose-finding studies is needed examine the maximum effect with minimal side effects. There is a lack of systemic absorption and possible statements to statements about systemic side effects.
I can’t imagine any drug company would be looking to get this approved for MPB, so if you’re interested, you’ll likely need to get a doctor to prescribe it, there is a generic for latanoprost available in the US.
so is this a higher or lower concentration of bimatoprost than is found in latisse? How many times more or less bimatoprost used on the test subjects scalps than found in lattise?
» Recently in Germany conducted studies on Latanoprost.
»
» Aktuelles - Haarerkrankungen.de
»
»
»
» google translation
»
» In the current study, a 0.1% solution for 24 weeks was used by the
» subjects. The study was single center, double-blind, randomized created.
» Each subject covered a small area of scalp with the
» latanoprost solution, a different, balanced on the other side of the head
» with a placebo solution. Study participants were 23 to 35 years old, with
» dark blond to light brown hair and a recently developed androgenetic
» alopecia Hamilton grade II to III. Determined, the rate of hair growth,
» hair density, telogen to anagen and diameter ratio using the Trichoscans.
» Übersichtphotografien were fabricated, evaluated the tolerability and hair
» pigmentation.
»
» Results:
» - After 24 weeks was demonstrated in the areas treated with latanoprost, a
» significant increase in hair density compared to baseline (starting at 8
» week, 24 weeks +22%) and compared with the placebo-treated areas.
» - Evidence of a non-significant decrease and increase in the Anagenhaarrate
» Telogenhaarrate in both treatment groups.
» - Appearance of redness in 5 patients in the treated areas with
» latanoprost.
»
» Assessment:
» Latanoprost is to increase the ability of young men with androgenetic
» alopecia, in particular, the hair counts. Prostaglandin analogs may thus
» with, which is latanoprost, a new group of drugs for the treatment of
» androgenetic alopecia (AGA) are available. But it is unclear whether the
» therapy in older men (it is assumed) and also in more advanced stages of
» AGA is effective. Equally unclear is whether latanoprost is similarly
» effective in other areas of the scalp. At 1/3 of the patients there is
» redness of the scalp in the area treated with latanoprost come. Prior to
» application outside of a precise dose-finding studies is needed examine the
» maximum effect with minimal side effects. There is a lack of systemic
» absorption and possible statements to statements about systemic side
» effects.
» I can’t imagine any drug company would be looking to get this approved for
» MPB, so if you’re interested, you’ll likely need to get a doctor to
» prescribe it, there is a generic for latanoprost available in the US.
» » I can’t imagine any drug company would be looking to get this approved
» for
» » MPB, so if you’re interested, you’ll likely need to get a doctor to
» » prescribe it, there is a generic for latanoprost available in the US.
»
»
» Doesn’t latanprost = bimatoprost?
» so is this a higher or lower concentration of bimatoprost than is found in
» latisse? How many times more or less bimatoprost used on the test subjects
» scalps than found in lattise?
»
This is NOT bimatoprost. Latanoprost.
Also this is generically available in US, so hopefully not expensive.
» » so is this a higher or lower concentration of bimatoprost than is
» found in
» » latisse? How many times more or less bimatoprost used on the test
» subjects
» » scalps than found in lattise?
» »
»
»
» This is NOT bimatoprost. Latanoprost.
»
» Also this is generically available in US, so hopefully not expensive.
They’re similar though. I think they both work by the same mode of action is what I mean. Also, they got 20% more hair with a .1% solution of latanoprost and that is a lot less active ingredient than minoxidil’s 5.0%. The amount of active latanoprost is about 1/50th as much as minoxidil in 5.0% rogaine so that means that .1% latanoptrost is at least 50 times as potent for hair growth as minoxidil. Keep in mind that the latanoprost .1% also grew more hair than 5% minoxidil does.
»
»
» They’re similar though. I think they both work by the same mode of action
» is what I mean. Also, they got 20% more hair with a .1% solution of
» latanoprost and that is a lot less active ingredient than minoxidil’s 5.0%.
» The amount of active latanoprost is about 1/50th as much as minoxidil in
» 5.0% rogaine so that means that .1% latanoptrost is at least 50 times as
» potent for hair growth as minoxidil. Keep in mind that the latanoprost .1%
» also grew more hair than 5% minoxidil does.
»
» Very interesting.
It’s probably more powerful than minox as it directly mimics prostaglandins I believe. Potentially could replace it. However, I doubt it will be approved for MPB, but it is worth experimenting with in lieu of bimatoprost, which is expensive.
» Anyways this is something that extends anagen phase, so should be something
» similar to minox, hopefully better.
But it works by the same mode of action as bimatoprost I believe and if that is the case then this bodes well for bimatoprost.
Also, it also means that if we had the guts to try a higher dose of latanprost we might do even better than the 20% regrowth that these test subjects got. They used a .1% dose so what would happen if you multiplied that dose by 10 and did 1% or even 50 and did 5%. Keep in mind that Rogaine has 5% minoxidil in its’ solution. I wonder what the highest safe topical dose of latanoprost is???
» Recently in Germany conducted studies on Latanoprost.
»
» Aktuelles - Haarerkrankungen.de
»
»
»
» google translation
»
» In the current study, a 0.1% solution for 24 weeks was used by the
» subjects. The study was single center, double-blind, randomized created.
» Each subject covered a small area of scalp with the
» latanoprost solution, a different, balanced on the other side of the head
» with a placebo solution. Study participants were 23 to 35 years old, with
» dark blond to light brown hair and a recently developed androgenetic
» alopecia Hamilton grade II to III. Determined, the rate of hair growth,
» hair density, telogen to anagen and diameter ratio using the Trichoscans.
» Übersichtphotografien were fabricated, evaluated the tolerability and hair
» pigmentation.
»
» Results:
» - After 24 weeks was demonstrated in the areas treated with latanoprost, a
» significant increase in hair density compared to baseline (starting at 8
» week, 24 weeks +22%) and compared with the placebo-treated areas.
» - Evidence of a non-significant decrease and increase in the Anagenhaarrate
» Telogenhaarrate in both treatment groups.
» - Appearance of redness in 5 patients in the treated areas with
» latanoprost.
»
» Assessment:
» Latanoprost is to increase the ability of young men with androgenetic
» alopecia, in particular, the hair counts. Prostaglandin analogs may thus
» with, which is latanoprost, a new group of drugs for the treatment of
» androgenetic alopecia (AGA) are available. But it is unclear whether the
» therapy in older men (it is assumed) and also in more advanced stages of
» AGA is effective. Equally unclear is whether latanoprost is similarly
» effective in other areas of the scalp. At 1/3 of the patients there is
» redness of the scalp in the area treated with latanoprost come. Prior to
» application outside of a precise dose-finding studies is needed examine the
» maximum effect with minimal side effects. There is a lack of systemic
» absorption and possible statements to statements about systemic side
» effects.
It’s from May last year. Latanoprost has a greater likelihood of darkening the iris than bimatoprost does; something to keep in mind if anyone has beautiful light eyes they’d prefer to keep
» »
» »
» » They’re similar though. I think they both work by the same mode of
» action
» » is what I mean. Also, they got 20% more hair with a .1% solution of
» » latanoprost and that is a lot less active ingredient than minoxidil’s
» 5.0%.
» » The amount of active latanoprost is about 1/50th as much as minoxidil
» in
» » 5.0% rogaine so that means that .1% latanoptrost is at least 50 times as
» » potent for hair growth as minoxidil. Keep in mind that the latanoprost
» .1%
» » also grew more hair than 5% minoxidil does.
» »
» » Very interesting.
»
»
» It’s probably more powerful than minox as it directly mimics prostaglandins
» I believe. Potentially could replace it. However, I doubt it will be
» approved for MPB, but it is worth experimenting with in lieu of
» bimatoprost, which is expensive.
»
»
» Prostaglandin analogs for hair growth: Great Expectations
Latanoprost is sitting there on the market, totally available, and it’s even cheap. It’s in a .1% solution but it would be easy to increase the dose just by applying more when you apply it, or by applying it more often, or a combination of both. In any case, it would be cheap to test to see if a higher dose would grow hair but who is going to test the higher dose. It might actually be a big breakthrough but who will test it at higher doses?
»
» Latanoprost is sitting there on the market, totally available, and it’s
» even cheap. It’s in a .1% solution but it would be easy to increase the
» dose just by applying more when you apply it, or by applying it more often,
» or a combination of both. In any case, it would be cheap to test to see if
» a higher dose would grow hair but who is going to test the higher dose. It
» might actually be a big breakthrough but who will test it at higher doses?
Go for it, I’d try it if I could get a script for it. Then again, my dermatologist doesn’t know the difference between proscar and avodart. fail.
» »
» » Latanoprost is sitting there on the market, totally available, and it’s
» » even cheap. It’s in a .1% solution but it would be easy to increase the
» » dose just by applying more when you apply it, or by applying it more
» often,
» » or a combination of both. In any case, it would be cheap to test to see
» if
» » a higher dose would grow hair but who is going to test the higher dose.
» It
» » might actually be a big breakthrough but who will test it at higher
» doses?
»
» Go for it, I’d try it if I could get a script for it. Then again, my
» dermatologist doesn’t know the difference between proscar and avodart.
» fail.
I can’t get a script for it and remember you would want to use a higher dose than .1% so you would need a lot of it.
Yes, there is generic Latanoprost, but it’s not cheap and it’s not 0.1% solution.
Unless you could tell me where I can buy 0.1% solution, all available online is 0.005% which according to studies had little or no impact on trialists?
Studies were completed last november.
» Yeah we need to use a dose 10x stronger than the one that is marketed, at
» least according to data in stump-tailed macaques.
It’s easier to grow hair on macaques than humans so you would have to go higher than 10x since it is harder to grow hair on humans. Also, it’s my recollection that the macaques did not get full regrowth at 10x the standard dose. They merely got marked regrowth. So that is another thing you would have to compensate for.
» Yes, there is generic Latanoprost, but it’s not cheap and it’s not 0.1%
» solution.
» Unless you could tell me where I can buy 0.1% solution, all available
» online is 0.005% which according to studies had little or no impact on
» trialists?
» Studies were completed last november.
.1% is not strong enough either. You should get some hair back but not enough to satisfy you. Would you be happy with just about 20% more hair? If you would then just maybe do Acell + PRP and it might get you 20% more hair. I think it is best to use at least 1% or even higher. Remember that rogaine is 5%.
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