Q: Do you have an update on your latest research about fgf-9?
No please refer to Dr. Cotsarelis Nature Medicine paper.
Q: MPB hair follicles grow as normal on immunodeficient mice is this because they do not produce pgd2?
That would be one guess that is potentially true given what we know.
Q: Why dont transplanted hairs get affected by pgd2?
The PGD2 does not travel very far, like all prostaglandins. Since transplanted hair bring their own dermis, they are spaced well from the high PGD2 follicles.
Q: Do you plan on testing(in the clinical trial) pro-growth factors (eg pge2) as well?
In the future If I had the funding I would do this.
Q: have you tested available substances on animal or human models to examine what happens when PGD2 or the GPR44 is inhibited.
We have no information on that at this moment.
Good ideas. Hopefully they work
Q:Does wounding and lithium grow terminal hairs?
Possible but we do not know.
Q:-You have demonstrated that Neogenesis+Lithium creates “neogenic-like” hair follicles in vivo in humans. Do these automatically become terminal hairs or is there another treatment necessary?
Not published yet so impossible to speculate.
Q:* Do you know anything about how your procedure will work on scalp areas which have already had HT work? Is normal HT recipient area scarring a major roadblock, possibly decreasing the density of the patch of new follicles generated? Growth direction issues? Etc? HT scarring varies from patient to patient but do you have any general comments?
HT should be fully compatible with any new technologies.
Q: in order to increase fgf9 what did you use in your experiments.
so far only wnts have been shown to turn on fgf9
and last one
Q:I want your future prediction about Is Follica going to put a breakthrough hair loss treatment into the marketplace in the next few months or years?
I would say years.