» » And if I read about time-released biotin one more time…(ALL of
» » Maxi-Hair is time-released…the niacin in it, being time-released, is
» » exactly a good thing. See previous posts on that)
» what would you rather do , release all the niacin at once? and stress your
» heart and blood vessels? or gradually release it?
» the first time you take a large amount of non timed release niacin all at
» once u will understand what i mean
» makes you flush red, nauseous, pricky skin…from the vasodilating
First of all…there is no-flush niacin out there. But this isn’t about that. You should know this, since it’s been brought up numerous times.
"Niacin is available in time-release tablets, and these products have less flushing reaction. These products release niacin slowly throughout the intestinal tract, which still presents the liver with a large niacin load. Simple, time-released niacin products have been associated with elevated liver enzymes in some users.
The niacin used in Schiff Flush Free Niacin is Inositol Hexanicotinate, a different kind of time-release niacin. Inositol hexanicotinate is absorbed by the body, and inside of tissues, enzymes normally present in all cells slowly release niacin from the inositol. This allows niacin from inositol hexanicotinate to avoid flushing and provide what the cells really want - niacin in the right place at the right time in the right amounts.
Niacinamide, another form of Vitamin B3 commonly used in dietary supplements and found in foods, does not cause flushing at any dose, but also does not have the cardiovascular health effects that niacin has. Niacin is involved in numerous reactions inside of cells that convert food into cellular energy. Niacin helps operate enzymes that transport and break down fats, carbohydrates, proteins and other molecules formed from food. A normal function of niacin is to help remove fats (triglycerides) from tissues and the bloodstream."
"Yet, because of the flush, some people have turned to time-released niacin. Yet I have also heard reports describing problems arising from this time-released niacin.
DURK: Yes. There were a few reports in medical journals; for example, one in JAMA reported on a few cases - I’m not sure about the exact number, but it was very small - where the subjects had elevated liver enzymes with time-released niacin. However, when they replaced the time-released niacin with regular niacin, the enzyme problems went away. Then when they returned to the time-released niacin, the liver problems returned. It was quite clear something was going on. Unless people have found out what the mechanism is or are willing to be tested over a period of time when they switch from regular niacin to the time-released niacin, they’re taking the chance of elevating their enzyme levels. We have no idea how many people could be affected by this type of problem."
"Some B vitamins have narrow absorption windows, so a time release pill might release them in the wrong place and they won’t get absorbed.
Once B vitamins get coenzymated, they stick around in the body for a long time so there’s no need to steadily dribble them into the system. I just take them in one dose like I would a fat-soluble vitamin.
We also know that the liver prefers to get niacin in an isolated chunk. Time release niacin is more toxic"
Now do you remember? :lookaround:
BTW…that “narrow absorption window” is another issue brought up before…for other nutrients as well.