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Here\'s one that i have a measure of high hopes for


#1

Sm04554

https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=364645


#2

Thanks for the info, jarjar.

Very interesting… the trials are taking place in Australia, but another company in San Diego appears to be behind this… Samumed

http://www.samumed.com/

San Diego is literally a hotbed of anti-MPB research!

This does look interesting, even though again it is a topical and not cell-based. But the Samumed website explains how their approach is to induce progenitor cells via the wnt pathway.


#3

I really WNT my pathways back. :frowning:


#4

A couple of quick observations about this:

  1. They say one of the study’s exclusion criteria is “males who are sexually active and have a partner who is capable of becoming pregnant”, and not on reliable birth control. So they think this stuff might cause birth defects or something? Not exactly sure why they put that caveat in there, but it might mean this product is suspected of being dangerous for use by any man who might get a woman pregnant. It also says that the subjects must be willing to inform any women they’re having sex with of the use of this product, as “potential harm to a fetus is unknown.” This does not look too good. If potential harm to a fetus is suspected as a possibility but unknown, it will most likely take many years to disprove the risk and get it through the FDA, if it happens at all.

  2. The measure they’re using for effectiveness is the increase in the number of non-vellus hairs. This also doesn’t sound too promising. Obviously, they have to have some way of assessing effectiveness, but you’d think they would know something about the potential of this product. If they’ve set the bar that low, it sounds like they’re not very optimistic about substantial regrowth. This makes it sound like yet another Minoxidil (and so many other topicals and drugs we’ve seen), where patients are desperately scrutinizing peach fuzz in the mirror for months and maybe years before they come to the conclusion that the stuff will never grow their hair back.