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» Jacob,
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» What do you know about silanol and its hair growth properties / mode of
» action?
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» Regards
» Pete
Not much…just what I’ve found below.
From a patent: http://www.patentstorm.us/patents/6001378-description.html
"Furthermore, the French patent FR-2,645,863 described silicon compounds in the form of molecular complexes of a silanol which are prepared by the reaction of an alkaline salt or ammonium salt of a silanol with an acid in the presence of a zeolite. These silanol complexes may, inter alia, be used for improving the re-growth of hair.
It is this type of complex which is used for the preparation of the product sold under the commercial trade name M 44 by Laboratoires CARILENE.
Such a product for stopping hair loss acts, due to the presence of organic silicon, as:
a tonic for the vascular walls, which leads to the improvement of the papillary vascularization,
a regulator of cell metabolism which favours the anagenic phase of the pilary cycle,
a stimulant of the synthesis of collagen and of elastin which enables the restructuration of the pilary stem,
a sebo-regulator, which leads to the decrease in the excess of sebum.
Pursuing his research with the view to improving the performances of the products for treating alopecia, the inventor of the present invention has noticed that combinations of peroxidised lipids and organic silicon derivatives, in particular silanol derivatives led to a considerable increase in the activities of the two products, enabling perfectly unexpected performances in the treatment of alopecia, in particular alopecia of the androgenetic type.
These combinations do in fact allow obtaining results at least equivalent to those obtained with minoxidil as well as preventing the drawbacks of the latter product, namely the lack of remanance of the observed effect once the treatment is stopped. Furthermore, another non-negligible advantage of these combinations with the respect to minoxidil is that they cause no increase in seborrhoea during treatment and necessitate only one application per day and not two.
A randomised controlled study of the effectiveness of these combinations has enabled demonstrating, without ambiguity, the effectiveness of these combinations. The effectiveness of these combinations was compared to that of minoxidil, the only current reference product in the treatment of androgenetic alopecia. The experimental method for making this comparison was that of phototrichograms, the only method recognised today as being perfectly reliable. The protocol and the results of this study are given in the examples of the present text.
Hence, according to a first aspect, the invention relates, as novel industrial product, to combinations of the two types of chemical products, namely peroxidised oils and organic silicon compounds, in particular silanol derivatives."
From another patent(or maybe from the same company as the other): Preparation for topical use with the function of combating hair loss - Guglielmo, Manuela
"[0028] Its purpose is to limit hardening of the tissues encouraging elasticisation of the follicle walls. In this way follicles are helped to maintain optimum physiological conditions for holding the hairs which they contain in their seats.
[0029] The cell-stimulating action of the complex of amino acids with silanol has been tested on human fibroblast cultures. The increase in cell growth was 46% when that active ingredient was present in the culture medium.
."
Here’s something else that seems to conain silanol: http://www.ar-pol.com/images/porost.pdf (search for it in there)
Silanols are also mentioned here: http://media.thecosmeticsite.com/documents/ATC_2005+Leonardi.pdf
i hope what’s inside as as good as whats on the outside.
