This article seems to cover the PRP-produced growth pretty well. I found other articles which list pretty much the same growth factors.
I do not see Wnt7a, I do not see noggin, I do not see KGF, I do not see follistatin. I do see VEGF but that is the only key hair growth factor I see in the bunch. Also, getting these growth factors in this manner (your own blood PRP or CRP) seem like it might be less certain because PRP/CRP may not actually contain these growth factors, rather the PRP/CRP is expected to cause the production of these growth factors. Injecting this PRP/CRP is hardly the same as injecting Wnt7a, Follistatin, noggin, KGF, and I even think that it is up in the air wether or not you even get VEGF out of the deal because they make the point that the growth factor yield from each person’s blood may be different as if to say that some people’s blood may or may not prove a good vehicle for producing growth factors or that in each individuals case the growth factors may be of different quality.
This seems iffy. I am not really impressed with PRP or CRP although i do think that there is a place for Acell in hair growth treatments but the doctors need to accept that they need to add external growth factors if they want to be sure they get the correct external growth factors into the skin. if they won’t add external growth factors it may be best to wait for histogen.
When doctors tell us that all these other growth factors (Wnt7a, follistatin, KGF, noggin) are inside PRP they’re on pretty shaky ground. I do not see these specific growth factors in PRP. No wonder the results are not as good as the results you see with Histogen.
The only major hair growth factor produced by PRP is VEGF and the quality of even that varies from patient to patient. This PRP stuff seems pretty useless so in my view it seems like in these Acell + PRP treatments the only thing of value is the Acell, but without getting the correct growth factors into the mix then I don’t see how Acell can do much of anything. If these docs don’t add external growth factors I’m not interested. Histogen is going put them all out of business in about 2 years.
I could be totally misunderstanding this. But, if these growth factors exist in blood plasma, shouldn’t wounding alone bring elevated levels of these growth factors to the skin?
If this is the case, just growth factors alone couldn’t grow hair because we still need the signal from the Wnt pathway.
If so, could this be one of the reasons of the skin reverting to an embryonic stage?
» Do you have any info on whether these growth factors are involved in wound
» healing?
I don’t know if these growth factors are involved in wound healing or not. I just know that you now have quite a few very good analysis of PRP and other than VEGF I see little reason for PRP to aid in hair growth. I see no other hair growth factors than VEGF inside of PRP, although at least there does appear to be VEGF inside of there perhaps. But there are other growth factors in PRP even through none of the other growth factors are key factors associated with hair growth.
These doctors need to add: lithium gluconate, KGF, folistatin, and noggin.
No wonder the Acell doctors are not getting the great results that Histogen is getting. They are not using most of Histogen’s hair growth factors at all. Histogen is going to blow them out of the water - put them all out of business. Only a fool would get Acell + PRP now that we see it lacks most of the key growth factors. What a laugh!!! I am not getting Acell + anything until I am 100% sure that they have found a way to add the necessary growth factors. I pity the fools that have wasted money on this stuff.
» I don’t know if these growth factors are involved in wound healing or not.
» I just know that you now have quite a few very good analysis of PRP and
» other than VEGF I see little reason for PRP to aid in hair growth. I see
» no other hair growth factors than VEGF inside of PRP, although at least
» there does appear to be VEGF inside of there perhaps. But there are other
» growth factors in PRP even through none of the other growth factors are key
» factors associated with hair growth.
No my point is, if these growth factors are indeed involved in wound healing. Then that means that Follica and Histogen might be doing the exact same pathway. What I mean is when you open a wound, are these growth factors brought to the wound site to repair? See what I’m getting at?
The key signal that is believed to trigger neogenesis is believed to be Wnt, and both companies are using it, hence my interest.
» » I don’t know if these growth factors are involved in wound healing or
» not.
» » I just know that you now have quite a few very good analysis of PRP and
» » other than VEGF I see little reason for PRP to aid in hair growth. I
» see
» » no other hair growth factors than VEGF inside of PRP, although at least
» » there does appear to be VEGF inside of there perhaps. But there are
» other
» » growth factors in PRP even through none of the other growth factors are
» key
» » factors associated with hair growth.
»
» No my point is, if these growth factors are indeed involved in wound
» healing. Then that means that Follica and Histogen might be doing the exact
» same pathway. What I mean is when you open a wound, are these growth
» factors brought to the wound site to repair? See what I’m getting at?
»
»
» The key signal that is believed to trigger neogenesis is believed to be
» Wnt, and both companies are using it, hence my interest.
Ok Wnt is great. There aint none in Acell + PRP. There also isn’t any KGF, follistatin, or noggin either. I don’t even know why they bother using PRP. i guess the VEGF is why, but it aint enough by itself.
I think we are going to be stuck waiting 2 years for histogen because these Acell docs aren’t going to add the external growth factors.
Doesn’t that reinforce the concept that there is a long hair gene? In your case, you were the only one that had it. Anomalies happen in families too, and that doesn’t mean it’s not genetic.
I wholeheartedly buy into the concept. My mom, who is a 3ab natural who has never put a chemical other than henna in her hair for color, has never had hair longer than BSL – and she hasn’t cut her hair or worn her hair down in 40 years. My older sister has relaxed her thick, 4b hair maybe twice in her 43 years has never gone beyond BSL. My little sister, who has been a 3c-4a natural for almost 4 years now, has, you guessed it, between APL-BSL hair.
I am relaxed for just over two years now, and it has been a struggle for me to reach and maintain APL; shoulder length is easy, but making it beyond that without extreme efforts (NO heat, PS 90% of the time, moisturizing every day and sleeping in a satin scarf every night) is damn near impossible. I still have hopes of reaching BSL and beyond, but I do believe I would be fighting my genetics in doing so.
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