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For Cal and TAGOHL


#1

I recieved getfitinib in the mail today. I’ll be trying it myself soon.

I intend to wound, wait three days…and then use getfitinib, an antihistamine, an anti-inflammatory (fish oil), finasteride, and minoxidil foam…which I will probably incorporate around day five or so. Im looking into an anti-microbial, but might just wash right before wouding with nizoral with some cedarwood oil therein before the wound. Ketoconazole was mentioned in the patent, so I dont think it would screw up the process being in evidence in the skin. Cedarwood is anti-microbail and anti-bacterial. I intend to water-wash for the next 7 days after wounding.

Thats it. If that doesnt’ work…Ive got cylcosporin ordered, but might try a topical immunosuppressant used for eczema.

Interesingly, the anti-histamine is correlated with interdicting some autoimmune responses if you read up on it.

I have a little hypothesis that the anti-histamine, anti-inflammatory, anti-microbial, antibacterial in the patent are to keep the immune system from getting interested in the wound so an immunosuppressant ISNT necessary. However, they add the immunosuppressant to the patnet just in case it ends up being needed anyway. Haroldo posted info once about how hair WOULD NOT FORM in baby mice if there was certain amounts of inflammation, thus he theorized COX inhibitors might be very helpful in hairloss. Ive seen patents that actually suggest anti-histamines and anti-microbials to TREAT hairloss, and apparently are filed under the belief that histamine inflammation in response to an event in the infidula (whatever antigen) is the reason for the immunological resonse to androgenic alopecia period. Thyme, interestingly enough, is supposed to be a natural antihistamine----but I dont want to use any topical that the patent doesnt explicity mention.

In the mice experiemetns, minox was used on day 11 and hair germs were detected on day 15. Day 11 is the post-epilithialization date in the mice, but it apparently comes much sooner in humans. As early as day 3 in the patent literature. I’ll probably do the minox on day four or five…depending on the depth of my wounding and what the abraded areas look like.

Well guys…assuming this is genuine getfitinib (Geftinat generic anyway) and not a phoney medication…I suppose this is it.
Wish me luck :lookaround:

BTW----Im not going to depilate beforehand on this pass…the two weird growth photos we’ve seen had plenty of density and they didn’t…plus I want to get the ball rolling.


#2

» I recieved getfitinib in the mail today. I’ll be trying it myself soon.
»
»
»
»
»
» I intend to wound, wait three days…and then use getfitinib, an
» antihistamine, an anti-inflammatory (fish oil), finasteride, and minoxidil
» foam…which I will probably incorporate around day five or so. Im
» looking into an anti-microbial, but might just wash right before wouding
» with nizoral with some cedarwood oil therein before the wound. Ketoconazole
» was mentioned in the patent, so I dont think it would screw up the process
» being in evidence in the skin. Cedarwood is anti-microbail and
» anti-bacterial. I intend to water-wash for the next 7 days after wounding.
»
»
»
»
» Thats it. If that doesnt’ work…Ive got cylcosporin
» ordered, but might try a topical immunosuppressant used for eczema.
»
»
»
» Interesingly, the anti-histamine is correlated with interdicting some
» autoimmune responses if you read up on it.
»
»
» I have a little hypothesis that the anti-histamine, anti-inflammatory,
» anti-microbial, antibacterial in the patent are to keep the immune system
» from getting interested in the wound so an immunosuppressant ISNT
» necessary. However, they add the immunosuppressant to the patnet just in
» case it ends up being needed anyway. Haroldo posted info once about how
» hair WOULD NOT FORM in baby mice if there was certain amounts of
» inflammation, thus he theorized COX inhibitors might be very helpful in
» hairloss. Ive seen patents that actually suggest anti-histamines and
» anti-microbials to TREAT hairloss, and apparently are filed under the
» belief that histamine inflammation in response to an event in the infidula
» (whatever antigen) is the reason for the immunological resonse to
» androgenic alopecia period. Thyme, interestingly enough, is supposed to be
» a natural antihistamine----but I dont want to use any topical that the
» patent doesnt explicity mention.
»
»
» In the mice experiemetns, minox was used on day 11 and hair germs were
» detected on day 15. Day 11 is the post-epilithialization date in the mice,
» but it apparently comes much sooner in humans. As early as day 3 in the
» patent literature. I’ll probably do the minox on day four or
» five…depending on the depth of my wounding and what the abraded areas
» look like.
»
»
»
» Well guys…assuming this is genuine getfitinib
» (Geftinat generic anyway) and not a phoney medication…I suppose
» this is it.
» Wish me luck :lookaround:
»
»
»
»
»
» BTW----Im not going to depilate beforehand on this pass…the two
» weird growth photos we’ve seen had plenty of density and they
» didn’t…plus I want to get the ball rolling.


#3

Sounds great Benji. Sounds like you will have covered everything short of the immunosuppressants with this round.

I think I may actually do the (topical) immunosuppressant next time. It’ll be a few more weeks for me though. I want to give my little test areas 2-2.5 months after the last abrasion before I hit them again.

(This long wait eventually might not turn out to be necessary. But if I don’t wait now and then nothing grows from the new attempt, it’ll just be another unwanted potential variable to wonder about.)


#4

» Sounds great Benji. Sounds like you will have covered everything short of
» the immunosuppressants with this round.
»
»
»
» I think I may actually do the (topical) immunosuppressant next time.
» It’ll be a few more weeks for me though. I want to give my little test
» areas 2-2.5 months after the last abrasion before I hit them again.
»
» (This long wait eventually might not turn out to be necessary. But if I
» don’t wait now and then nothing grows from the new attempt, it’ll just be
» another unwanted potential variable to wonder about.)

Anyone going to try immunosuppressants internally? I guess that would the last thing one would try. I just can’t imagine the technique will try to go through NDA with immuno’s taken internally. How are you planning on applying the immuno’s? Are you putting them on separately throughout the day or mixing it with the getfitinib?


#5

I Benji, i appreciate your try… but we need some before picture too… it don’t cost nothing, but is important for a final reliability of your work…
good luck!


#6

(Benji I guess this won’t apply to you if you’re not gonna depilate this time)

About the “before” pictures . . .

I wanted to mention to everyone that any “before” pictures would really need to be taken BEFORE any depilation as well as before the wounding itself. We need to see the truly original situation of the area in order evaluate what the test did. No point in depilating ___ hairs per cm and then praising Folica when that same amount re-sprouts again in a month.

Last time I almost forgot to do the before pics before the depilation.


#7

»
» BTW----Im not going to depilate beforehand on this pass…the two
» weird growth photos we’ve seen had plenty of density and they
» didn’t…plus I want to get the ball rolling.

I’ve my objections on this benji, are you sure they did’t ? First women do tend to depilate their noses quite often.As for the cancer patient he might had been a hard rasor shaving addict …is’t that a kind of depilation ?

Anyway that’s nota big deal as Baccy is going to try the depilation next round, so let’s see how it evolves for both and compare.

Good LUCK benj !


#8

One Question ,
Maybe it has no relation with this matter but I have to ask it.

We know that hair follicles are created in our body while we are still fetus.
We also know that MPB is due to a reaction of the inmune system.
why don´t we just wonder what is the difference between the inmune system of a fetus, wich allow to create a hair, and the inmune adult system?

Maybe it just work as an allergie, and should be enought the wound plus antihistaminic.

Just my opinion


#9

benji, are you gonna take drugs orally or apply them topically?


#10

» I recieved getfitinib in the mail today. I’ll be trying it myself soon.
»
»
»
»
»
» I intend to wound, wait three days…and then use getfitinib, an
» antihistamine, an anti-inflammatory (fish oil), finasteride, and minoxidil
» foam…which I will probably incorporate around day five or so. Im
» looking into an anti-microbial, but might just wash right before wouding
» with nizoral with some cedarwood oil therein before the wound. Ketoconazole
» was mentioned in the patent, so I dont think it would screw up the process
» being in evidence in the skin. Cedarwood is anti-microbail and
» anti-bacterial. I intend to water-wash for the next 7 days after wounding.
»
»
»
»
» Thats it. If that doesnt’ work…Ive got cylcosporin
» ordered, but might try a topical immunosuppressant used for eczema.
»
»
»
» Interesingly, the anti-histamine is correlated with interdicting some
» autoimmune responses if you read up on it.
»
»
» I have a little hypothesis that the anti-histamine, anti-inflammatory,
» anti-microbial, antibacterial in the patent are to keep the immune system
» from getting interested in the wound so an immunosuppressant ISNT
» necessary. However, they add the immunosuppressant to the patnet just in
» case it ends up being needed anyway. Haroldo posted info once about how
» hair WOULD NOT FORM in baby mice if there was certain amounts of
» inflammation, thus he theorized COX inhibitors might be very helpful in
» hairloss. Ive seen patents that actually suggest anti-histamines and
» anti-microbials to TREAT hairloss, and apparently are filed under the
» belief that histamine inflammation in response to an event in the infidula
» (whatever antigen) is the reason for the immunological resonse to
» androgenic alopecia period. Thyme, interestingly enough, is supposed to be
» a natural antihistamine----but I dont want to use any topical that the
» patent doesnt explicity mention.
»
»
» In the mice experiemetns, minox was used on day 11 and hair germs were
» detected on day 15. Day 11 is the post-epilithialization date in the mice,
» but it apparently comes much sooner in humans. As early as day 3 in the
» patent literature. I’ll probably do the minox on day four or
» five…depending on the depth of my wounding and what the abraded areas
» look like.
»
»
»
» Well guys…assuming this is genuine getfitinib
» (Geftinat generic anyway) and not a phoney medication…I suppose
» this is it.
» Wish me luck :lookaround:
»
»
»

Benji- Can you please give more specifics on your protocol? Abrasion: method, specific administration. Where you got the getfitinib; dosage etc, an
antihistamine; what brand, dosage etc, an anti-inflammatory (fish oil), finasteride, and minoxidil; when and how do these get applied, brand and dosage. Just curious as I want to try this myself. Thanx again.


#11

» One Question ,
» Maybe it has no relation with this matter but I have to ask it.
»
» We know that hair follicles are created in our body while we are still
» fetus.
» We also know that MPB is due to a reaction of the inmune system.
» why don´t we just wonder what is the difference between the inmune system
» of a fetus, wich allow to create a hair, and the inmune adult system?
»
» Maybe it just work as an allergie, and should be enought the wound plus
» antihistaminic.
»
» Just my opinion

i’ve not posted this because i’m not sure - but i remember i 've read during the development of certain organ immune system is at very low level.

Maybe is obvious ,maybe is not , i’m not an expert but we should find the answer w/o too much trouble.


#12

» »
» »
» »
»
»
» Benji- Can you please give more specifics on your protocol? Abrasion:
» method, specific administration. Where you got the getfitinib; dosage etc,
» an
» antihistamine; what brand, dosage etc, an anti-inflammatory (fish oil),
» finasteride, and minoxidil; when and how do these get applied, brand and
» dosage. Just curious as I want to try this myself. Thanx again.

Last night I did a TCA peel (25%), and waited six damned minutes (they only want you to do it for 4). In a few spots, the stuff should have been on 7 minutes. To be certain the abrasion was “enough”, I went back over it all with some sandpaper this afternoon. You shouldn’t be anywhere near bleeding, but your skin should get pretty red during the abrasion. If its not crusting some by day three…you probably didn’t go deep enough.

If you followed the patent, here is what you would do:

You would depilate, and wait three days.

On the fourth days, you’d wound. I’d also suggest getting on finas at this
time.

About day 3 or 4 or 5 thereafter (depending on whether keratinocytes are covering the wounded area as described in the patent), you’d start taking getfitinib or whatever egf-antagonist you can get your hands on. You’d also start taking an antihistamine, an anti-inflammatory. Clariton and Aleve would be two right off the top of my head. Parabens in shampoo could act as antibacterials for you if you use shampoo in this time. I think washing with nizoral and leaving it in for a few minutes before you wound would take care of any microbials during the experimental period because keto stays in the dermis for about seven days. Applying minox to the wound around day 4 or 5 might be a good idea also. Its mentioned in the patent.

Keep using the stuff for a good six or seven days thereafter for certain. 10 is the longest they mention in the patent.

Thats about it. If you get hair, you’d probably be seeing it after about one month’s time.

If this doesnt’ work, then Im pretty sure they will end up having to use an immunosuppressant like the patent allowed for. Hopefully just a topical one.


#13

In regards to both the immunosuppressants and the EGF-R drugs, Let’s just hope all this stuff can work topically alone. If not, then we’re unlikely to get a commerical product out of it any time soon.

Although I might still try stuff at home orally if that’s what it required. I wonder if a milder oral dose combined with a strong topical dose might do the job. Oral EGF-R inhibition didn’t mess me up when I tried it last month, and immunosuppressants probably won’t wreck me in a week or two either as long as I’m healthy to begin with.

Either way I’m still very hopeful that it’ll work topically. We all know there are topical immune suppression drugs for other things already. And Gentifilib looks like it’ll probably go that way too. So it all seems to add up to a likely topical option.

Folica itself must also think so if they’re expecting a commercial product from this project any time soon.


#14

» In regards to both the immunosuppressants and the EGF-R drugs, Let’s just
» hope all this stuff can work topically alone. If not, then we’re unlikely
» to get a commerical product out of it any time soon.
»
» Although I might still try stuff at home orally if that’s what it
» required. I wonder if a milder oral dose combined with a strong topical
» dose might do the job. Oral EGF-R inhibition didn’t mess me up when I tried
» it last month, and immunosuppressants probably won’t wreck me in a week or
» two either as long as I’m healthy to begin with.
»
»
»
»
»
» Either way I’m still very hopeful that it’ll work topically. We all know
» there are topical immune suppression drugs for other things already. And
» Gentifilib looks like it’ll probably go that way too. So it all seems to
» add up to a likely topical option.
»
» Folica itself must also think so if they’re expecting a commercial product
» from this project any time soon.

The “kit” patent calls for everything to be a topical. Nothing internal. Thats a good indication of what their hopes are. However Im sure they would resort to an internal if it proves necessary, but it probably wont.


#15

It is very probbably that there is something, becouse then, why the mother inmune system doesn´t attack the fetus? Or why the fetus inmmune system doesn´t react against mother´s fluids?.

SOmething related to the supression of the inmune system, or the IGG ( Allergy ) is what doesn´t let the stem cells in the adult to create new follicles.

It could also be possible that by the time that some company will put in the market a drug to avoid creation og IGGs or antobodies against transplanted organs, by cheating the body to recognice this new organ as a own organ, they will also discover as a side effect of the drug that big wounds in scalp in places where formerly had hair, new hair will grow.

» » One Question ,
» » Maybe it has no relation with this matter but I have to ask it.
» »
» » We know that hair follicles are created in our body while we are still
» » fetus.
» » We also know that MPB is due to a reaction of the inmune system.
» » why don´t we just wonder what is the difference between the inmune
» system
» » of a fetus, wich allow to create a hair, and the inmune adult system?
» »
» » Maybe it just work as an allergie, and should be enought the wound plus
» » antihistaminic.
» »
» » Just my opinion
»
» i’ve not posted this because i’m not sure - but i remember i 've read
» during the development of certain organ immune system is at very low
» level.
»
» Maybe is obvious ,maybe is not , i’m not an expert but we should find the
» answer w/o too much trouble.


#16

Good luck m8.


#17

» » »
» » »
» » »
» »
» »
» » Benji- Can you please give more specifics on your protocol? Abrasion:
» » method, specific administration. Where you got the getfitinib; dosage
» etc,
» » an
» » antihistamine; what brand, dosage etc, an anti-inflammatory (fish oil),
» » finasteride, and minoxidil; when and how do these get applied, brand
» and
» » dosage. Just curious as I want to try this myself. Thanx again.
»
»
»
»
» Last night I did a TCA peel (25%), and waited six damned minutes (they
» only want you to do it for 4). In a few spots, the stuff should have been
» on 7 minutes. To be certain the abrasion was “enough”, I went back over it
» all with some sandpaper this afternoon. You shouldn’t be anywhere near
» bleeding, but your skin should get pretty red during the abrasion. If its
» not crusting some by day three…you probably didn’t go deep
» enough.
»
»
» If you followed the patent, here is what you would do:
»
» You would depilate, and wait three days.
»
» On the fourth days, you’d wound. I’d also suggest getting on finas at
» this
» time.
»
» About day 3 or 4 or 5 thereafter (depending on whether keratinocytes
» are covering the wounded area as described in the patent), you’d start
» taking getfitinib or whatever egf-antagonist you can get your hands on.
» You’d also start taking an antihistamine, an anti-inflammatory. Clariton
» and Aleve would be two right off the top of my head. Parabens in shampoo
» could act as antibacterials for you if you use shampoo in this time. I
» think washing with nizoral and leaving it in for a few minutes before you
» wound would take care of any microbials during the experimental period
» because keto stays in the dermis for about seven days. Applying minox to
» the wound around day 4 or 5 might be a good idea also. Its mentioned in the
» patent.
»
»
» Keep using the stuff for a good six or seven days thereafter for
» certain. 10 is the longest they mention in the patent.
»
»
»
» Thats about it. If you get hair, you’d probably be seeing it after about
» one month’s time.
»
»
»
»
»
»
» If this doesnt’ work, then Im pretty sure they will end up having to
» use an immunosuppressant like the patent allowed for. Hopefully just a
» topical one.

Thanks Benji. BTW where did you get the getfitinib?


#18

» » » »
» » » »
» » » »
» » »
» » »
» » » Benji- Can you please give more specifics on your protocol? Abrasion:
» » » method, specific administration. Where you got the getfitinib; dosage
» » etc,
» » » an
» » » antihistamine; what brand, dosage etc, an anti-inflammatory (fish
» oil),
» » » finasteride, and minoxidil; when and how do these get applied, brand
» » and
» » » dosage. Just curious as I want to try this myself. Thanx again.
» »
» »
» »
» »
» » Last night I did a TCA peel (25%), and waited six damned minutes
» (they
» » only want you to do it for 4). In a few spots, the stuff should have
» been
» » on 7 minutes. To be certain the abrasion was “enough”, I went back over
» it
» » all with some sandpaper this afternoon. You shouldn’t be anywhere near
» » bleeding, but your skin should get pretty red during the abrasion. If
» its
» » not crusting some by day three…you probably didn’t go deep
» » enough.
» »
» »
» » If you followed the patent, here is what you would do:
» »
» » You would depilate, and wait three days.
» »
» » On the fourth days, you’d wound. I’d also suggest getting on finas
» at
» » this
» » time.
» »
» » About day 3 or 4 or 5 thereafter (depending on whether keratinocytes
» » are covering the wounded area as described in the patent), you’d start
» » taking getfitinib or whatever egf-antagonist you can get your hands on.
» » You’d also start taking an antihistamine, an anti-inflammatory.
» Clariton
» » and Aleve would be two right off the top of my head. Parabens in
» shampoo
» » could act as antibacterials for you if you use shampoo in this time. I
» » think washing with nizoral and leaving it in for a few minutes before
» you
» » wound would take care of any microbials during the experimental period
» » because keto stays in the dermis for about seven days. Applying minox
» to
» » the wound around day 4 or 5 might be a good idea also. Its mentioned in
» the
» » patent.
» »
» »
» » Keep using the stuff for a good six or seven days thereafter for
» » certain. 10 is the longest they mention in the patent.
» »
» »
» »
» » Thats about it. If you get hair, you’d probably be seeing it after
» about
» » one month’s time.
» »
» »
» »
» »
» »
» »
» » If this doesnt’ work, then Im pretty sure they will end up having to
» » use an immunosuppressant like the patent allowed for. Hopefully just a
» » topical one.
»
»
» Thanks Benji. BTW where did you get the getfitinib?

Benji, dou you think to use DMSO to dissolve in gefitinib ?


#19

» I recieved getfitinib in the mail today. I’ll be trying it myself soon.

What about the lung issues associated with this drug? Aren’t you concerned about that anymore? Are you planning on taking the drug orally or topically?


#20

Well, I did read up about the lung (and overall death!) dangers before I took oral Leflunomide, which is the same situation as Genfilitib.

I came away thinking that the EGF-R drugs probably aren’t causing them in EVERY user. Probably not like Finasteride side effects. (I think Fin is probably always technically causing at least some amount of sides for everyone, and the only question is whether or not it’s enough for the user to feel it.)

I got the impression that the EGF-R lung risks have mainly been a problem where the users were starting out of the gate with notably compromised lungs to begin with. (Like, sometimes because of the rheumatoid arthritis that the drug is being administered to treat in the first place.) I came away thinking that a healthy set of lungs probably won’t be very vulnerable to the same damage.

I’m also totally caucasian. Asians have a worse risk of this damage than whites apparently.

In the case of Leflunomide, they’ve had this drug on the market for like 10 years and it’s been administered to over 200,000 people. Most of them for months and years at a time, not just the 10 days we’re talking about. It’s hurt some people, but they’re not having any big Vioxx-style widespread epidemic of lung damage over it.

So I just said “f*ck it” and swallowed the stuff. It’s been a month since I finished and there’s no lung damage that I can tell.