Home | News | Find a Doctor | Ask a Question | Free

FOLLICA - Bald scalp retains hair follicle stem cells/ lacks progenitor cells


#1

Source http://www.follicabio.com/news/follica-co-founder-and-scientific-advisor-george-cotsarelis-md-publishes-new-research-on-hair-follicle-stem-cells-in-ithe-journal-of-clinical-investigationi-44/

Follica Co-founder and Scientific Advisor, George Cotsarelis, M.D. Publishes New Research on Hair Follicle Stem Cells in The Journal of Clinical Investigation
(Tuesday, January 04, 2011) PHILADELPHIA - In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, M.D., chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, Follica co-founder and Scientific Advisory Board member, has found that hair follicle stem cells are preserved in bald scalp from men. These findings, based on studies of human cell samples from bald scalp and non-bald scalp, showed that bald areas had the same number of stem cells as normal scalp in the same person, but lacked a more mature cell type called a progenitor. These findings support Follica’s approach towards treating androgenetic alopecia, which targets activation of stem cells to induce hair follicle neogenesis.


http://www.jci.org/articles/view/44478


#2

"An overseas human clinical study of Follica’s drug-device combo treatment for baldness is under way, Ju says. He declined to share key specifics of the ongoing study, such as where exactly it is taking place, yet he did say that the firm eventually plans to pursue approval of the treatment in the U.S.

“I will say that the trial is being done in a very quality fashion outside the United States,” Ju says. “They are being done under the same standards as one would see in the United States under FDA [oversight].”

SOURCE - xconomy


#3

Hey rev, I thought you’re pissed about Follica?

I’ve never ever been pissed about Follica:

http://www.hairsite.com/hair-loss/board_entry-id-68449.html#p68449


#4

» Hey rev, I thought you’re pissed about Follica?
Follica’s lack of transparency has always pissed me off.

» I’ve never ever been pissed about Follica:
» http://www.hairsite.com/hair-loss/board_entry-id-68449.html#p68449
Congrats. Do you want a cookie lol? j/k.


#5

» » Hey rev, I thought you’re pissed about Follica?
» Follica’s lack of transparency has always pissed me off.
»
»
» » I’ve never ever been pissed about Follica:
» » http://www.hairsite.com/hair-loss/board_entry-id-68449.html#p68449
» Congrats. Do you want a cookie lol? j/k.

Thanks rev, but I have to refuse:

During the christmas time, I think I’ve eaten too much ‘cookies’ (it seems my girls baked too good cookies!). So, currently I try to “break up” the result of all these good cookies with alcohol, concerning occured overweight …


#6

» "An overseas human clinical study of Follica’s drug-device combo
» treatment for baldness is under way, Ju says. He declined to share key
» specifics of the ongoing study, such as where exactly it is taking place,
» yet he did say that the firm eventually plans to pursue approval of the
» treatment in the U.S.
»
» “I will say that the trial is being done in a very quality fashion outside
» the United States,” Ju says. “They are being done under the same standards
» as one would see in the United States under FDA [oversight].”

»
» SOURCE - xconomy

Finally! Some progress. Guess that was what the harvard trial back in 08 was all about.

But “under way” means soon to start, right? If so why are they talking of a “ongoing study”?. Confused.

Still. Good news from Follica!


#7

» » "An overseas human clinical study of Follica’s drug-device combo
» » treatment for baldness is under way, Ju says. He declined to share key
» » specifics of the ongoing study, such as where exactly it is taking
» place,
» » yet he did say that the firm eventually plans to pursue approval of the
» » treatment in the U.S.
» »
» » “I will say that the trial is being done in a very quality fashion
» outside
» » the United States,” Ju says. “They are being done under the same
» standards
» » as one would see in the United States under FDA [oversight].”

» »
» » SOURCE - xconomy
»
» Finally! Some progress. Guess that was what the harvard trial back in 08
» was all about.
»
» But “under way” means soon to start, right? If so why are they talking of a
» “ongoing study”?. Confused.
»

No, Z79, under way here means it’s already started, it’s ongoing.


#8

» Source
» http://www.follicabio.com/news/follica-co-founder-and-scientific-advisor-george-cotsarelis-md-publishes-new-research-on-hair-follicle-stem-cells-in-ithe-journal-of-clinical-investigationi-44/
»
» Follica Co-founder and Scientific Advisor, George Cotsarelis, M.D.
» Publishes New Research on Hair Follicle Stem Cells in The Journal of
» Clinical Investigation

» (Tuesday, January 04, 2011) PHILADELPHIA - In a new study, published in the
» Journal of Clinical Investigation, a team led by George Cotsarelis, M.D.,
» chair of the Department of Dermatology at the University of Pennsylvania
» School of Medicine, Follica co-founder and Scientific Advisory Board
» member, has found that hair follicle stem cells are preserved in bald scalp
» from men. These findings, based on studies of human cell samples from bald
» scalp and non-bald scalp, showed that bald areas had the same number of
» stem cells as normal scalp in the same person, but lacked a more mature
» cell type called a progenitor. These findings support Follica’s approach
» towards treating androgenetic alopecia, which targets activation of stem
» cells to induce hair follicle neogenesis.
»
» http://www.eurekalert.org/pub_releases/2011-01/uops-mpb010311.php
» http://www.jci.org/articles/view/44478

I hope they have ideas clear ,it doesn’t seem so

http://www.docstoc.com/docs/20346195/263_1_


#9

» I hope they have ideas clear ,it doesn’t seem so
»
»
» http://www.docstoc.com/docs/20346195/263_1_

It confirms my theory that MPB is related to the immune system attacking the hair follicle. That’s the ‘burning’ sensation we feel in our scalp and is consistent with the view that the follicle is treated as a foreign pathogen :

“Consistent with the loss of immunosurpressive CD200 protein, array based expression profiling demonstrates significant increase in inflammation associated genes in androgenic alopecia”.


#10

» » I hope they have ideas clear ,it doesn’t seem so
» »
» »
» » http://www.docstoc.com/docs/20346195/263_1_
»
» It confirms my theory that MPB is related to the immune system attacking
» the hair follicle. That’s the ‘burning’ sensation we feel in our scalp and
» is consistent with the view that the follicle is treated as a foreign
» pathogen :
»
» “Consistent with the loss of immunosurpressive CD200 protein, array based
» expression profiling demonstrates significant increase in inflammation
» associated genes in androgenic alopecia”.

MPB and Androgenic Alopecia is not the same condition.


#11

»
» MPB and Androgenic Alopecia is not the same condition.

Yes it is.