Here is what I think of Exosomes.
On the Alvi Armani website, there is one set of “before and after” photos of a patient treated with Exosomes. The truth is, that there is almost no difference at all in the two pictures!
The only differences appear to be that in the “after” photo, the hair is a little bit darker. You can see that in the first photo, the patient had some gray hair. In the second photo, he appears to have died his hair dark brown or black, eliminating the gray. So it looks as if some of the bald areas grew some hair because of the color change. But if you really look carefully, there is no real difference in the size of the bald areas between the “before” and “after” photos.
I think what they are doing with Exosomes is this: They realize that stem cells are highly regulated, very much restricted by the FDA, and that it’s expensive and time consuming to get permission to use real stem cells. Plus, stem cells are not yet approved for use in hair treatments because they are still experimental, and several applications may be currently under study (such as Stemson Therapeutics), but none has been approved yet.
So they are using these exosomes, which are really cell fragments (portions of cells without a nucleus), to get around the restrictions on stem cell use in hair loss treatments. Exosomes are just fragments so they are not cells, and have no genetic material. Therefore it is easy for Alvi Armani (and maybe others) to use them. There is no time-consuming and expensive research and clinical trials process. No overhead for these hair transplant doctors. They can just isolate the exosomes and go.
NOW, the question is “Do exosomes really work?” And my answer is “Probably not”. There is no evidence that they work. This is all just speculation. It’s not speculation based on nothing, but it’s speculation based on very, very little.
They are speculating because they think that fragments of certain cells (possibly some stem cells and other cells) might contain some of the products of stem cells, like growth factors. And they are speculating that, even though these exosomes might have small amounts of these growth factors, those small amounts will be enough to grow hair for patients.
BUT just because they speculate this, and show a few pictures (which really aren’t great - in fact like I said if you look closely, they show no real difference) then that does not mean that hair will actually grow.
This kind of speculation is not reality, though. It’s just marketing to sell a treatment.
That’s my opinion about Exosomes.