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Dr. Proctor

Any thoughts on topical dutasteride? Any way to limit systemic absorption with new technology, liposomes etc? Thanks

» Any thoughts on topical dutasteride? Any way to limit systemic absorption
» with new technology, liposomes etc? Thanks

I tried it, hair felt slightly thicker but don’t know for sure if it grew any hair or slowed down my hair loss.

» » Any thoughts on topical dutasteride? Any way to limit systemic
» absorption
» » with new technology, liposomes etc? Thanks
»
» I tried it, hair felt slightly thicker but don’t know for sure if it grew
» any hair or slowed down my hair loss.

Thanks ABC, did you have any side effects from systemic absortion?

» Any thoughts on topical dutasteride? Any way to limit systemic absorption
» with new technology, liposomes etc? Thanks

My wild guess it that, like finasteride, any effects fron topical dutasteride will be mostly due to systemic absorbtion. The problem is that the hair follicle is a major site of systemic absorbtion of topical agents. This makes it difficult to separate one from the other, particularly considering the weeks-long half-life of finasteride is much longer than any skin absorbtion time.

This is not true for spironolactone, partially because the agent is metabolized by skin to inactive products as it is absorbe systemically.

Peter H Proctor, PhD,MD

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