Dr. Cole will be in NYC on 7/20 - only 2 remaining appointments available for the much sought after exosome therapy.
Dr. Cole will be in New York City July 20 to provide consultations, discuss repair work, and provide regenerative medicine options for patients.
Exosome therapy is the latest in cell based regenerative medicine. Many in the stem cells research community consider Exosomes as the key ingredient for a varietly of anti-aging regenerative therapy including PRP, Amniotic Membrane, and Adipose Stem Cells. Dr. Cole is the first on HairSite to offer Exosome therapy for patients with hair loss or thinning hair.
Exosome Basics
Exosomes are small membrane vesicles secreted by most cell types. Notably, they contain proteins, lipids and genetic material of cytoplasmic origin. These nanoparticles are present in biological fluids wherein they travel to distant tissues and are involved in multiple physiological and pathological processes dictated by the cell-type-dependent proteins present on their surfaces.
From Formation to Target
Extracellular vesicles are formed either by budding of the plasma membrane, in which case they are known as ectosomes, shed vesicles, or microvesicles, or by the inward budding of intraluminal vesicles (IVE) within multivesicular endosomes (MVE).
When MVE fuse with the plasma membrane, ILV are released as exosomes. Alternatively, MVE can fuse with lysosomes, which degrade their contents. Once released, exosomes can enter a target cell in one of two ways: by being taken up by the target cell’s endocytic pathway or by fusing to the target cell’s membrane and releasing its contents directly into the cytoplasm.
Role of Exosomes in Anti-Aging Therapies
In the context of anti-aging treatments, exosomes offer a cell-free therapeutic strategy to enhance tissue regeneration, thereby mitigating the unwanted effects of aging while avoiding the risks of cell-based therapies. The many beneficial effects exosomes can provide include:
• Reversal of skin fibroblast aging resulting from UV-induced damage by increasing the expression of collagen type I and reducing expression of collagen-degrading enzymes MMP-1 and MMP-2 [1];
• Stimulation of fibroblast proliferation and migration [2], accelerating skin wound healing [3];
• Highly effective promotion and enhancement of hair growth, cycling, and regeneration by regulating follicular cell activity [4,5];
• Modulation of melanocyte pigmentation, providing a path to address hyper- and hypopigmentation skin disorders [6]
4 months after Adipose Stem Cells and Amniotic Membrane
For more information about Exosomes therapy for hair loss and thinning hair or to book your appointment for this Saturday July 20th’s treatment session in New York City, contact 800-368-4247 or email consults@forhair.com