July 16, 2008 - Cytomedix maintains an intellectual property portfolio of seven U.S. Patents, and comparable international patents, covering a range of advanced tissue regeneration technologies, including wound care, angiogenesis, hair growth and anti-inflammatory therapies.
Both Patents are IDENTICAL:
Method for promoting hair growth. US Patent 4,957,742 - 18.09.90
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=4,957,742.PN.&OS=PN/4,957,742&RS=PN/4,957,742
Method for promoting hair growth . US Patent 5,178,883 - 12.01.93.
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,178,883.PN.&OS=PN/5,178,883&RS=PN/5,178,883
Abstract
Platelet enriched plasma is produced from blood. The platelets are activated by thrombine which causes therelease of platelet-derived growth and angiogenesis factors. A carrier such as a microcrystalline collagen is added to produce a wound-treating salve. The composition is applied directly to wounds and initiates healing in nonhealing wounds as well as accelerating normal wound-healing by increasing vascularization, stimulating fibroblast mitrosis and migration, and increasing collagen synthesis by fibroblasts. The composition is also applied to tissue to facilitate the growth of hair.
Topical application of the compositions to areas of tissue containing hair follicles has also been found to promote hair growth where no growth or limited growth was previously observed.
EXAMPLE IV
A diabetic patient who had received a renal transplant and had had a below the knee amputation (“BKA”) was treated with a composition prepared as described above. The composition was applied to the patient’s stump, including a portion of tissue containing hair follicles, for a period of approximately 31/2 months. After treatment, significant hair growth was observed in the area of treatment with the composition where no hair had previously been observed.
EXAMPLE V
Four patients were treated with a composition prepared as described above, with the exception that the platelet buffer used did not contain human serum albumin.
In all four patients, after treatment, significant hair growth was observed in the area of treatment with the composition where NO hair had previously been observed.
Angiogenic peptides . US Patent 5,470,831 - 28.11.95
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,470,831.PN.&OS=PN/5,470,831&RS=PN/5,470,831
Selecting amounts of platelet releasate for efficacious treatment of tissue . US Patent 5,599,558 - 04.02.97
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,599,558.PN.&OS=PN/5,599,558&RS=PN/5,599,558
Anti-inflammatory peptides . US Patent 5,776,892 - 07.07.98
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,776,892.PN.&OS=PN/5,776,892&RS=PN/5,776,892
Enriched platelet wound healant . US Patent 6,303,112 - 16.10.01
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6,303,112.PN.&OS=PN/6,303,112&RS=PN/6,303,112
Enriched platelet wound healant . US Patent 6,524,568 - 25.02.03
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=6,524,568.PN.&OS=PN/6,524,568&RS=PN/6,524,568