» » ok but why there are people in their 50 and 60 that didn’t loss even
» one
» » hair (like my dad, im nw 5)and there hair will keep cycling and cycling
» » until they’ll die. ?
»
» No. Your genetic code, during replication, is unable to replicate a fair
» amount of information due to the fact that the replicating enzymes attached
» at the ends are too large to allow for complementary base pairing in this
» region. As a result, evolution has create things called “telomeres” at the
» end of each DNA strand. These telomeres are basically useless DNA
» information, which, even if lost doesn’t affect the genetic code. However,
» after a number of cycles/replications, you run out of telomeres. This is
» when your proteins malfunction due to loss of genetic code, and you reach
» senescence. This is why old people have weaker bones, get hurt easily, have
» wispy hair etc. And I think you guys are confusing this fact with lack of
» follicle cycling. It is possible that if the hair cells are mass replicated
» that they can start malfunctioning due to telomere loss. But this would
» require a crapload of replications. I think it would also depend on your
» age and current status in terms of telomere loss.
This is actually not true for stem cells where the telomerase enzyme compensates for the telomere loss by adding subsequent sequences to the end which are generated from the enzymes’ own RNA. And as new follicles would have to be created from the follicles’ stem cell, this would actually not pose a problem.
» » Thanks Ahab, for the detailed explanation.
» » Yes, now understand it perfectly.
» » According to your experience, and your comment on scarring alopecia,
» the
» » fixed number of cycles make sense.
» »
» » I then assume, when women repeatedly wax their legs, they will end up
» with
» » scarring alopecia too in their legs?
»
» It should, IF what I’ve read about scarring alopecia is true and if waxing
» is the same as plucking hair, which I believe it is.
Yes, it seems waxing eventually kills follicles.
Two possible reasons come to my mind: could be because increased cycling, or because the DP is damaged and cycling is distorted.
From a quick Google search:
Body Waxing. Beauty Therapy Guide, Holistic Therapy Review, Beauty … Prolonged waxing can kill the hair follicle thus reducing hair regrowth. Hair should be at least 1/2 of an inch long for successful waxing. … www.gelisy.com/waxing.htm - Cached - Similar
Bikini wax?
12 posts - 7 authors
Electrolysis is the only method that will kill the follicle. Bikini and underarm hair reduce friction in the area. By waxing the area you may increase the … www.cyclingforums.com › … › Bikes › Women’s Cycling - Cached - Similar
Get more discussion results
Kill Hair Follicles - Ask.com
Jump to Does waxing kill the hair follicle: Continuous waxing (years and years of it) can eventually kill the hair follicle. … www.ask.com/questions-about/Kill-Hair-Follicles - Cached - Similar
Laser Hair Removal: Does Laser Hair Removal Work?
Because lasers kill the follicle, hair won’t grow back causing in-grown hairs you get with waxing (waxing damages the follicle, it doesn’t always kill it … Exactly What to Expect When Undergoing Laser Hair Removal - Cached - Similar
» » » Thanks Ahab, for the detailed explanation.
» » » Yes, now understand it perfectly.
» » » According to your experience, and your comment on scarring alopecia,
» » the
» » » fixed number of cycles make sense.
» » »
» » » I then assume, when women repeatedly wax their legs, they will end up
» » with
» » » scarring alopecia too in their legs?
» »
» » It should, IF what I’ve read about scarring alopecia is true and if
» waxing
» » is the same as plucking hair, which I believe it is.
»
» Yes, it seems waxing eventually kills follicles.
» Two possible reasons come to my mind: could be because increased cycling,
» or because the DP is damaged and cycling is distorted.
» From a quick Google search:
»
» Google
»
» >>>>>>
» #
» Body Waxing. Beauty Therapy Guide, Holistic Therapy Review, Beauty …
» Prolonged waxing can kill the hair follicle thus reducing hair
» regrowth. Hair should be at least 1/2 of an inch long for successful
» waxing. …
» www.gelisy.com/waxing.htm - Cached - Similar
» #
» Bikini wax?
» 12 posts - 7 authors
» Electrolysis is the only method that will kill the follicle. Bikini and
» underarm hair reduce friction in the area. By waxing the area you may
» increase the …
» www.cyclingforums.com › … › Bikes › Women’s Cycling - Cached - Similar
» Get more discussion results
» #
» Kill Hair Follicles - Ask.com
» Jump to Does waxing kill the hair follicle: Continuous waxing
» (years and years of it) can eventually kill the hair follicle. …
» www.ask.com/questions-about/Kill-Hair-Follicles - Cached - Similar
» #
» Back Waxing Vs. Laser Hair Removal | LIVESTRONG.COM
» 3 Jan 2010 … Waxing damages a hair follicle; the hair that regrows
» will generally be finer and thinner. Eventually waxing can kill hair
» follicles. …
» Does Hair Eventually Stop Growing With Waxing? | LEAFtv - Cached
» #
» Laser Hair Removal: Does Laser Hair Removal Work?
» Because lasers kill the follicle, hair won’t grow back causing in-grown
» hairs you get with waxing (waxing damages the follicle, it doesn’t
» always kill it …
» Exactly What to Expect When Undergoing Laser Hair Removal - Cached - Similar
»
» <<<<<<<
It sounds just like a form of trachea alopecia. The answer is stop plucking or waxing it! I think that if a hair is multiplied using hair from the donor area then it should be fine. No matter what the age men always keep a certain amount of hair in the donor area. For now my biggest concern is that they can actually multiply the hair and ge it to grow again properly, i’ll worry about other possible negatives after that!
» » one thing about this theory that makes absolutely no sense to me is that
» » if i were to clone a follicle ONCE it would have half the cycles and if
» i
» » clone it TWICE it would have one forth and so on. By cloning the cell i
» » shld receive an identical cell which has exactly the same properties as
» the
» » first… and not half of its properties. By definition the new cell
» should
» » have the exact dna as the first cell and be equivalent and not reduce
» the
» » first cells abilities.
»
»
» Admittedly, that is the weakest part of what I said.
»
» But I still believe there’s a good case for a limited number of cycles as
» the explanation for other things, like senescent allopecia, traction
» allopecia, and could also be the mechanism by which DHT causes mpb and
» other phenomena (see the reply I just made to Spanish Dude).
»
» Could be that when you try to make hair follicles, it is not as simple as
» cloning cells to reconsruct where such a cycle count is stored in the
» follicle.
For this reason the baldness “cure” will never be solved by rejuvenation… because what follicles are you actually rejuvenating but old “cycled” out hair follicles. The true cure will come, I believe, from the neogenesis process from the concepts of the likes of Histogen or Follica where you start the cycling process back to square one.
» » » Thanks Ahab, for the detailed explanation.
» » » Yes, now understand it perfectly.
» » » According to your experience, and your comment on scarring alopecia,
» » the
» » » fixed number of cycles make sense.
» » »
» » » I then assume, when women repeatedly wax their legs, they will end up
» » with
» » » scarring alopecia too in their legs?
» »
» » It should, IF what I’ve read about scarring alopecia is true and if
» waxing
» » is the same as plucking hair, which I believe it is.
»
» Yes, it seems waxing eventually kills follicles.
» Two possible reasons come to my mind: could be because increased cycling,
» or because the DP is damaged and cycling is distorted.
» From a quick Google search:
»
» Google
»
» >>>>>>
» #
» Body Waxing. Beauty Therapy Guide, Holistic Therapy Review, Beauty …
» Prolonged waxing can kill the hair follicle thus reducing hair
» regrowth. Hair should be at least 1/2 of an inch long for successful
» waxing. …
» www.gelisy.com/waxing.htm - Cached - Similar
» #
» Bikini wax?
» 12 posts - 7 authors
» Electrolysis is the only method that will kill the follicle. Bikini and
» underarm hair reduce friction in the area. By waxing the area you may
» increase the …
» www.cyclingforums.com › … › Bikes › Women’s Cycling - Cached - Similar
» Get more discussion results
» #
» Kill Hair Follicles - Ask.com
» Jump to Does waxing kill the hair follicle: Continuous waxing
» (years and years of it) can eventually kill the hair follicle. …
» www.ask.com/questions-about/Kill-Hair-Follicles - Cached - Similar
» #
» Back Waxing Vs. Laser Hair Removal | LIVESTRONG.COM
» 3 Jan 2010 … Waxing damages a hair follicle; the hair that regrows
» will generally be finer and thinner. Eventually waxing can kill hair
» follicles. …
» Does Hair Eventually Stop Growing With Waxing? | LEAFtv - Cached
» #
» Laser Hair Removal: Does Laser Hair Removal Work?
» Because lasers kill the follicle, hair won’t grow back causing in-grown
» hairs you get with waxing (waxing damages the follicle, it doesn’t
» always kill it …
» Exactly What to Expect When Undergoing Laser Hair Removal - Cached - Similar
»
» <<<<<<<
I suspect that scientists simply assumed repeated plucking of hair somehow damages follicles–somehow scarring the follicles deep inside–and that sufficed in their minds to eplain why repeatedly plucked follicles stop growing hair.
Scientists probably didn’t bother to look harder for an explanation, because the hair being plucked was unwanted anyway, so who cares if plucked or waxed follicles eventually stop growing for good.
» » » Thanks Ahab, for the detailed explanation.
» » » Yes, now understand it perfectly.
» » » According to your experience, and your comment on scarring alopecia,
» » the
» » » fixed number of cycles make sense.
» » »
» » » I then assume, when women repeatedly wax their legs, they will end up
» » with
» » » scarring alopecia too in their legs?
» »
» » It should, IF what I’ve read about scarring alopecia is true and if
» waxing
» » is the same as plucking hair, which I believe it is.
»
» Yes, it seems waxing eventually kills follicles.
» Two possible reasons come to my mind: could be because increased cycling,
» or because the DP is damaged and cycling is distorted.
» From a quick Google search:
»
» Google
»
» >>>>>>
» #
» Body Waxing. Beauty Therapy Guide, Holistic Therapy Review, Beauty …
» Prolonged waxing can kill the hair follicle thus reducing hair
» regrowth. Hair should be at least 1/2 of an inch long for successful
» waxing. …
» www.gelisy.com/waxing.htm - Cached - Similar
» #
» Bikini wax?
» 12 posts - 7 authors
» Electrolysis is the only method that will kill the follicle. Bikini and
» underarm hair reduce friction in the area. By waxing the area you may
» increase the …
» www.cyclingforums.com › … › Bikes › Women’s Cycling - Cached - Similar
» Get more discussion results
» #
» Kill Hair Follicles - Ask.com
» Jump to Does waxing kill the hair follicle: Continuous waxing
» (years and years of it) can eventually kill the hair follicle. …
» www.ask.com/questions-about/Kill-Hair-Follicles - Cached - Similar
» #
» Back Waxing Vs. Laser Hair Removal | LIVESTRONG.COM
» 3 Jan 2010 … Waxing damages a hair follicle; the hair that regrows
» will generally be finer and thinner. Eventually waxing can kill hair
» follicles. …
» Does Hair Eventually Stop Growing With Waxing? | LEAFtv - Cached
» #
» Laser Hair Removal: Does Laser Hair Removal Work?
» Because lasers kill the follicle, hair won’t grow back causing in-grown
» hairs you get with waxing (waxing damages the follicle, it doesn’t
» always kill it …
» Exactly What to Expect When Undergoing Laser Hair Removal - Cached - Similar
»
» <<<<<<<
Even though my cycling hypothesis may be weakest when used as a possible reason HM is so hard to achieve, nonentheless I seem to remember–I could be wrong–but I seem to remember some years ago that hair production fades with each generation of multiplied cells.
Dude, am I remembering wrong?
If not, my cycle limit might explain why hair production fades with each generation of multiplied cells.
The issue of cloned tissue/creatures aging prematurely has always had my attention. I think the medical research community is prone to ignoring it because it’s just so godd*mn inconvenient in the face of all the possibilities that cloning holds.
» The issue of cloned tissue/creatures aging prematurely has always had my
» attention. I think the medical research community is prone to ignoring it
» because it’s just so godd*mn inconvenient in the face of all the
» possibilities that cloning holds.
I remember reading many decades ago that the single-cell organism, paramecium, which ordinarily reproduces via cell division (mitosis, if I remember aright), when individually isolated and left to reproduce again and again (with “offspring” of each generation being isolated in-turn) was found to lose vitality after many divisions.
Then researchers then discovered that when each isolated paramecia were introduced to other paramecia, they enganged in a primitive form of sexual reproduction: they exchanged celluar material (I supposed genetic) with each other, which reivived them.
The conclusion drawn was that paramecia can only reproduce by division a limited number of times before failing unless they also periodically exchange celluar material with each other.
Now I did read this very long ago, so it’s possible the info may since have since been disproven–but I suspect it’s still valid.
» » The issue of cloned tissue/creatures aging prematurely has always had my
» » attention. I think the medical research community is prone to ignoring
» it
» » because it’s just so godd*mn inconvenient in the face of all the
» » possibilities that cloning holds.
»
» I remember reading many decades ago that the single-cell organism,
» paramecium, which ordinarily reproduces via cell division (mitosis, if I
» remember aright), when individually isolated and left to reproduce again
» and again (with “offspring” of each generation being isolated in-turn) was
» found to lose vitality after many divisions.
»
» Then researchers then discovered that when each isolated paramecia were
» introduced to other paramecia, they enganged in a primitive form of sexual
» reproduction: they exchanged celluar material (I supposed genetic) with
» each other, which reivived them.
»
» The conclusion drawn was that paramecia can only reproduce by division a
» limited number of times before failing unless they also periodically
» exchange celluar material with each other.
»
» Now I did read this very long ago, so it’s possible the info may since
» have since been disproven–but I suspect it’s still valid.
Actually I think you may have misunderstood the point of the article. Taking an educated guess, I would assume this study was done as a comparison between asexual reproduction vs sexual reproduction in the single-celled organism. Natural selection, in many organisms, favors sexual reproduction. This is study of natural selection in WHOLE organisms, and not just follicular units.
» Even though my cycling hypothesis may be weakest when used as a possible
» reason HM is so hard to achieve, nonentheless I seem to remember–I could
» be wrong–but I seem to remember some years ago that hair production fades
» with each generation of multiplied cells.
»
» Dude, am I remembering wrong?
»
» If not, my cycle limit might explain why hair production fades with each
» generation of multiplied cells.
I have always read that DP cells, when expanded in a petri dish, lose quickly their hair-inducing capabilities. Suppossedly, ICX was able to multiply DP cells in high numbers maintaining their hair inducing potential. But in spite of this, TRC failed.
I think, if the correct replication method is used, it will be possible to multiply all kind of cells without problems. But I am no expert.
» » » The issue of cloned tissue/creatures aging prematurely has always had
» my
» » » attention. I think the medical research community is prone to
» ignoring
» » it
» » » because it’s just so godd*mn inconvenient in the face of all the
» » » possibilities that cloning holds.
» »
» » I remember reading many decades ago that the single-cell organism,
» » paramecium, which ordinarily reproduces via cell division (mitosis, if
» I
» » remember aright), when individually isolated and left to reproduce
» again
» » and again (with “offspring” of each generation being isolated in-turn)
» was
» » found to lose vitality after many divisions.
» »
» » Then researchers then discovered that when each isolated paramecia were
» » introduced to other paramecia, they enganged in a primitive form of
» sexual
» » reproduction: they exchanged celluar material (I supposed genetic) with
» » each other, which reivived them.
» »
» » The conclusion drawn was that paramecia can only reproduce by division
» a
» » limited number of times before failing unless they also periodically
» » exchange celluar material with each other.
» »
» » Now I did read this very long ago, so it’s possible the info may since
» » have since been disproven–but I suspect it’s still valid.
»
» Actually I think you may have misunderstood the point of the article.
» Taking an educated guess, I would assume this study was done as a
» comparison between asexual reproduction vs sexual reproduction in the
» single-celled organism. Natural selection, in many organisms, favors sexual
» reproduction. This is study of natural selection in WHOLE organisms, and
» not just follicular units.
Paramecia are single-cell organisms. That is, their “WHOLE” organism is a single cell.
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