I think if you have fully inductive cells, it wouldn’t matter as much.
One thing I learned in biology is that on the cellular scale, which is incredibly small, but with incredibly large numbers of cells involved, is that you have to think of EVERYTHING that happens on a statistical basis. You have to think of tens of millions of cells moving into the skin, and a Bell-curve distribition of where they will go and what happens to them.
In any typical cell injection, you might be injecting tens of millions of cells, say 50 million. Let’s say 40 million drift away from the follicle so they’re essentially wasted and get flushed out by the blood and lymph. 10 million come very close to the “sweet spot” of the follicle (the bottom, near the dermal papilla), but only 2 million actually hit that part follicle and of those, only 1 million or less stick to it.
Now if the cells are poorly inductive, like Aderans’ and Intercytx’s cells, that means that say out of 10 million cells, maybe only 1 million are inductive and 9 million are waste.
But with Stemson’s cells, maybe out of 10 million, 8 or 9 million are inductive and 1-2 million are not.
Let’s say it takes at least 500,000 to 1 million inductive cells to hit and convert a follicle from miniature to terminal.
Because EVERYTHING in cell biology is based on statistics, and I mean everything.
So if you inject the poorly inductive cell culture from Aderans, 9/10 are waste from the get-go, so with the high attrition rate of injected cells tending not to hit and stick to their targets, as I mentioned above, and the poor fraction of inductive cells in the population, you will get an extremely low yield. You might grow 1 or 2 hairs after many injections and get really frustrated and just give up, which is what they did.
But with Stemson’s cells, they are not shooting duds, so despite the inherent very low rate of injected cells hitting and sticking to their targets, the fraction of inductive cells in the population is very high, so the ones that do hit and stick will almost certainly be inductive.
EVERYTHING in cell biology is about populations and statistics!