Hair health and wellness is the reflection of one’s social behaviour. The Cosmetic Industry and more specially - the field of hair cosmetics - is currently turning its attention to anti-hair loss products. Associated with the loss of physical force and power, hair loss starts at an early age and may very rapidly progress to total baldness.
SILAB, renowned for its expertise in the field of active ingredients from natural origin, has developed an anti-hair loss active ingredient extracted from white sweet lupine. ANAGELINE® rich in glutaminated peptides, trace elements and vitamins, has the power to revitalize hair growth.
To fight against alopecia, ANAGELINE®activates the anagen phase and acts simultaneously on the 3 principal factors controlling the hair cycle: hormone balance, vascular system and cell metabolism.
ANAGELINE® restores the hormonal balance. Tested at 0.25% on human fibroblasts ANAGELINE® shows a significant inhibiting effect (-18%) on the activity of 5α -reductase II, an enzyme responsible for the follicles miniaturization characteristic of androgenic alopecia.
ANAGELINE® improves the vascularization of the hair follicle. It stimulates the synthesis of a vascular growth factor, VEGF, that enables the vascular system development and favors the supply of nutrients. Tested at 0,5%, ANAGELINE®leads to a 30% increase of the synthesis of VEGF.
ANAGELINE® favors keratinization and hair growth. Tested at 1% on cultured keratinocytes, ANAGELINE® boosts the expression of mRNA coding for type 1 tranglutaminase (+44%), a marker of keratinocyte differentiation. By improving cell metabolism, ANAGELINE® stimulates hair growth.
Thanks to its simultaneous action on three essential factors of the hair cycle, ANAGELINE® favors hair growth. This effect has been proven in vivo after 12 weeks of treating balding subjects with ANAGELINE®. The study has shown a significant effect on hair density, shown by an increase in the number of hairs and an increase in the anagen/telogen ratio. ANAGELINE®, a genuine revitalizing cocktail to stimulate hair re-growth.
With its fully integrated R&D, Production and Marketing, SILAB is the perfect partner for the development of your next innovative, trend catching and effective active cosmetic products.