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2007 TERMIS Anual meeting (was Sept. 4th- 7th) Interctex present

Dermal papilla cells of the adult hair follicle have the capacity to induce the formation of hair follicles when combined with keratinocytes in vivo. This remarkable regenerative ability forms the basis of a cell therapy, Follicular Cell Implantation (FCI), in which cells from a few dermal papillae are expanded in culture to produce cells from which many new follicles can form. Proof of principle for this therapy comes from research demonstating hair growth using culture dermal papilla cells combined with a variety of different keratinocyte sources to generate new follicles in different experimental models. A major challenge in the development of FCI is the ability to generate thousands of new follicles after a single therapy session. In order to accomplish this, the efficiency of hair growth must be high and the implants must be easy to perform. We have developed a method to generate immature hair-like structures or “proto-hairs” in culture. Proto-hairs form after the incubation of mixed aggregates, which consist of dermal papilla cells and keratinocytes that combine spontaneously under appropriate conditions. Initially, the mixed aggregrates have no structure and the dermal papilla cells and keratinocytes are randomly mixed within them. After 5-7 days in culture, proto-hairs form that have hair-like features including a dermal papilla, hair matrix, and a rudimentary hair shaft. When proto-hairs are implanted in an animal model, visible hairs emerge within 10-14 days. Proto-hairs represent a convenient form in which cultured follicular cells can be inplanted to produce new follicles with high efficiency.

On the Pdf. scroll to the bottom of page 33 and top corner of 34.

Thank you, Minitor. This is great, and you’re great for posting it.

See how much more advanced the Europeans (including the British) are than the US, in the field of cell therapy. They are leaving us IN THE DUST, because of the Luddites, naysayers, and greedheads in the US who can’t focus on anything except their immediate profits.


This is also why Detroit is tanking and the Japanese, Koreans, Germans, etc. make much better cars than we do. And why they’re all building hybrids, while the US is still stuck in the era of the gas-guzzling SUV.

America is no longer a land of innovators. We’re no longer the “land of the free and the home of the brave.” Now, we’re the land of the willingly-manipulated, and the home of the timid.



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