The reason for optimism that you guys seem to fabricate out of thin hair, is a product of overactive imaginations, and extreme hope and desperation to get something that works.
based on past predictions, and their failure to materialize, the 100 percent failure, as a matter of fact, and based on the fact that nothing currently being looked at even remotely is close to being cosmetically effective or acceptable or successful…
nothing is going to happen in 5 yrs. 20 yrs maybe
go on with your lives and stop dreaming