You wrote this in the long argument thread below:
"Oh my dear lord!! Right, lets make this perfectly clear.
- THEORETICALLY, ECM PROMOTES TISSUE GROWTH.
- ACELL REPRESENTED THE MOST ADVANCED FORM OF THIS TECHNOLOGY AT THE TIME,
- THE IDEA THAT THIS WOULD WORK WAS A PERFECTLY REASONABLE ONE!!!
- SO THE IDEA OF INFORMING DOCTORS AND RAISING PUBLICITY WAS A GOOD ONE!"
Right. All of that would be true if there was any indication, or any scientific reason to believe, that ECM could promote NEW HAIR GROWTH (i.e., grow new follicles), in addition to promoting tissue growth at wound sites.
But there is/was ABSOLUTELY NO REASON TO ASSUME THIS, OR TO BELIEVE IT!!!
What ECM does is allows the cells involved in healing to coalesce better at the edge of the wound, where healing naturally occurs. These cells are of different types, but pretty generic, and they lay down a pretty generic type of new tissue… it’s just SKIN. The ECM provides a physical framework, like a lattice, so that it’s easier for these generic epithelial cells, or skin cells, to lay down together, line up, coalesce, and form healthy new tissue. THERE IS NO INDICATION THAT IT NEW FOLLICLES ARE PRODUCED!!!
Growing a new follicle is much different than just laying down the network to allow generic epithelial cells to grow together to form new healthy (as opposed to scarry) tissue.
Forming a new follicle is a MUCH DIFFERENT process, which involves very specialized types of cells, e.g., DP cells, keratinocytes, etc. which have to coalesce in a very specific way, and germinate into a hair follicle. This is a very complex, three-dimensional process which requires all the many multiple complicated factors to come together in perfect alignment, as during embryonic and fetal (foetal) development in the uterus.
In order for this to even have a remote chance of happening during wound healing, with the addition of ECM, you would have to actually add these cells by injection or some other way (as in HM or hair cloning), and then “pray”, because even then it may or may not happen, depending on whether the pre-follicular cells can coalesce together into a new follicle.
But the experiments Willy and Acell were talking about, going back to Dr. Jones experiments and then all the bogus hype from Drs. Cooley and Hitzig, didn’t even bother to use injected or implanted DP or any other kind of specialized follicular cells from a good donor area… they just relied on the ECM alone, as if that would miraculously produce not just new tissue at the wound site, but also somehow new hair follicles.
There is ABSOLUTELY NO SCIENTIFIC BASIS TO ASSUME THIS… sure, the experiment was worth it, but any good scientist with a knowledge of these areas, like a Dr. Washenik, Dr. Kemp, or some other scientist with knowledge would probably bet his own testicles that without adding the crux of the issue, i.e., donor cells from good follicles, THIS WON’T HAVE MUCH OF A CHANCE AT ALL OF PRODUCING NEW FOLLICLES.
But because Willy was just some random guy with a lot of enthusiasm, but no scientific knowledge (not even BASIC scientific knowlege about tissues, histology, etc.), he just jumped to a huge conclusion right away and set forth to promote this process like some kind of crazy street preacher on speed.
He jumped right into the fray and began promoting this sh*t to all kinds of doctors and to Acell, and guess what??? They bit at the bait because it was potentially very LUCRATIVE ($$$$) for both sides, never mind the fact that scientifically it rests on very rickety legs and doesn’t pan out when you do a real, level-headed scientific analysis of it.