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Stem Cell "Gun" Grows New Skin


#1

On National Geographic (WARNING: there is video of some skin burns, so if you’re squeamish, just know that in advance … though it isn’t too bad):

http://www.megaupload.com/?d=59SFGC5F (for those who can’t access the above clip).

For burn victims, scientists now have a “gun-like” device that sprays a stem cell solution onto burned skin and regenerates the skin.

Of course if it’s regenerating skin … I’d assume it’s probably also might be regenerating the hair follicles on the skin … (the regenerated skin looked pretty normal to me).

It’s still in the test phase but it has been used on actual humans with success (as you can see in the video), not just lab rats.


#2

Good find. A solution seems to coming closer and closer


#3

» On National Geographic (WARNING: there is video of some skin burns, so if
» you’re squeamish, just know that in advance … though it isn’t too bad):
»
» http://www.youtube.com/watch?v=eXO_ApjKPaI&feature=player_embedded
»
» http://www.megaupload.com/?d=59SFGC5F (for those who can’t access the above
» clip).
»
» For burn victims, scientists now have a “gun-like” device that sprays a
» stem cell solution onto burned skin and regenerates the skin.
»
» Of course if it’s regenerating skin … I’d assume it’s probably also might
» be regenerating the hair follicles on the skin … (the regenerated skin
» looked pretty normal to me).
»
» It’s still in the test phase but it has been used on actual humans with
» success (as you can see in the video), not just lab rats.

did the skin contain new hair follicles?


#4

What I don’t understand is that why is it so easy to identify the skin stem cells and so difficult for scientists to identify hair stem cells? I think right now the problem is that scientists are unable to find hair stem cells, otherwise Intercytex or even Gho would have been successful a long time ago already.


#5

» What I don’t understand is that why is it so easy to identify the skin stem
» cells and so difficult for scientists to identify hair stem cells? I think
» right now the problem is that scientists are unable to find hair stem
» cells, otherwise Intercytex or even Gho would have been successful a long
» time ago already.

WRONG - Dr. Gho found out that what Intercytex is doing (“dermal papilla cells crap” ) resp. what Intercytex’s “head consultant” is suggesting, can’t work! :smiley:

Unfortunately, that’s the truth - and lots of other researchers confirmed that in the meanwhile.


#6

» What I don’t understand is that why is it so easy to identify the skin stem
» cells and so difficult for scientists to identify hair stem cells? I think
» right now the problem is that scientists are unable to find hair stem
» cells, otherwise Intercytex or even Gho would have been successful a long
» time ago already.

There are a lot of stem cell procedures springing up but the science behind it regrowing hair is not established.

The doctor in the video appears to be injecting what’s supposedly stem cells derived from the patient.

But we have already seen the study recently that balding heads do not lack stem cells per say but rather hair progenitor cells.

I guess stem cells might be of use to hair follicles which are struggling to survive and on the verge of death. But we really need before-after pictures and a study of this whole stem cell injecting issue to determine fact from fiction.


#7

» » What I don’t understand is that why is it so easy to identify the skin
» stem
» » cells and so difficult for scientists to identify hair stem cells? I
» think
» » right now the problem is that scientists are unable to find hair stem
» » cells, otherwise Intercytex or even Gho would have been successful a
» long
» » time ago already.
»
» There are a lot of stem cell procedures springing up but the science behind
» it regrowing hair is not established.
»
» The doctor in the video appears to be injecting what’s supposedly stem
» cells derived from the patient.
»
» But we have already seen the study recently that balding heads do not lack
» stem cells per say but rather hair progenitor cells.
»
» http://www.youtube.com/watch?v=AinVWcvK0QM
»
» I guess stem cells might be of use to hair follicles which are struggling
» to survive and on the verge of death. But we really need before-after
» pictures and a study of this whole stem cell injecting issue to determine
» fact from fiction.

Another article on this procedure:

http://www.mirm.pitt.edu/news/article.asp?qEmpID=328

“What we’re doing is taking the cells, isolating them, and, in the same procedure on the same day, we’re putting the cells onto the wound,” Dr. Gerlach says. “The progenitor cells can act immediately. The most critical cells are present, and we are using those cells right away from the patient. We just need to take care that we are distributing the cells nicely over the wound.” Hence, the spray nozzle.

Hmmm. Sounds like he is using progenitor cells.

I could be wrong but doesn’t all skin contain some number of hair follicles? Even areas that appear hairless still are covered with fine hairs.


#8

» » What I don’t understand is that why is it so easy to identify the skin
» stem
» » cells and so difficult for scientists to identify hair stem cells? I
» think
» » right now the problem is that scientists are unable to find hair stem
» » cells, otherwise Intercytex or even Gho would have been successful
» a long
» » time ago already.
»
» WRONG - Dr. Gho found out that what Intercytex is doing (“dermal papilla
» cells crap” ) resp. what Intercytex’s “head consultant” is suggesting,
» can’t work! :smiley:
»
» Unfortunately, that’s the truth - and lots of other researchers confirmed
» that in the meanwhile.

Can’t you read? I never said dermal papilla cells, where in my post did I mention dermal papilla?


#9

» » » What I don’t understand is that why is it so easy to identify the skin
» » stem
» » » cells and so difficult for scientists to identify hair stem cells? I
» » think
» » » right now the problem is that scientists are unable to find hair stem
» » » cells, otherwise Intercytex or even Gho would have been
» successful

» » a long
» » » time ago already.
» »
» » WRONG - Dr. Gho found out that what Intercytex is doing (“dermal papilla
» » cells crap” ) resp. what Intercytex’s “head consultant” is suggesting,
» » can’t work! :smiley:
» »
» » Unfortunately, that’s the truth - and lots of other researchers
» confirmed
» » that in the meanwhile.
»
» Can’t you read?

Yes, I can. And you?

» I never said dermal papilla cells,
» where in my post did I mention dermal papilla?

You didn’t mention it, right, but I mentioned it in brackets. And I mentioned it in brackets, because dermal papilla cells 1) aren’t hair-stem cells 2) nor could any researcher ever found any in a human DP. That’s the reason why DPC’s “lose their identity” and die soon once outside the body. Intercytex did never ever researched any stem cells (they are responsible for the reproduction for hair!) within a human hair follicle. That’s the reason why they failed in their trails.


#10

» On National Geographic (WARNING: there is video of some skin burns, so if
» you’re squeamish, just know that in advance … though it isn’t too bad):
»
» http://www.youtube.com/watch?v=eXO_ApjKPaI&feature=player_embedded
»
» http://www.megaupload.com/?d=59SFGC5F (for those who can’t access the above
» clip).
»
» For burn victims, scientists now have a “gun-like” device that sprays a
» stem cell solution onto burned skin and regenerates the skin.
»
» Of course if it’s regenerating skin … I’d assume it’s probably also might
» be regenerating the hair follicles on the skin … (the regenerated skin
» looked pretty normal to me).
»
» It’s still in the test phase but it has been used on actual humans with
» success (as you can see in the video), not just lab rats.

Thanks for also posting the megaupload link, NatGeo didn’t work for me. That was amazing and clearly this is the future for skin healing/regeneration for burn victims. 4 days, gets normal looking skin back-I didn’t notice any ugly scarring on that patient (as one often sees with burn victims). It really looks miraculous. Even if it can’t be applied to hair loss at least it’s a cure for burns and perhaps even cosmetic surgery/scar repair.

Personally I see no reason why this can’t also work for curing baldness. If they take a patch of skin from the region where permanent hair grows, culture it and spray it on the bald areas, it should grow new hair because it’ll have both the stem and progenitor cells.

Of course it’ll probably require extensive wounding or perhaps the dermabrasion of the top layer of skin for it to work. Not an inviting prospect but if it’s the cure, then I’d be willing to do whatever it takes.

Somebody should get in touch with this doctor and ask if it can be applied to our purposes (fixing hair loss). So often these researcher types are narrowly focused on their treatment, they don’t think about other potential applications.


#11

» » On National Geographic (WARNING: there is video of some skin burns, so
» if
» » you’re squeamish, just know that in advance … though it isn’t too
» bad):
» »
» » http://www.youtube.com/watch?v=eXO_ApjKPaI&feature=player_embedded
» »
» » http://www.megaupload.com/?d=59SFGC5F (for those who can’t access the
» above
» » clip).
» »
» » For burn victims, scientists now have a “gun-like” device that sprays a
» » stem cell solution onto burned skin and regenerates the skin.
» »
» » Of course if it’s regenerating skin … I’d assume it’s probably also
» might
» » be regenerating the hair follicles on the skin … (the regenerated skin
» » looked pretty normal to me).
» »
» » It’s still in the test phase but it has been used on actual humans with
» » success (as you can see in the video), not just lab rats.
»
» Thanks for also posting the megaupload link, NatGeo didn’t work for me.
» That was amazing and clearly this is the future for skin
» healing/regeneration for burn victims. 4 days, gets normal looking skin
» back-I didn’t notice any ugly scarring on that patient (as one often sees
» with burn victims). It really looks miraculous. Even if it can’t be applied
» to hair loss at least it’s a cure for burns and perhaps even cosmetic
» surgery/scar repair.
»
» Personally I see no reason why this can’t also work for curing baldness. If
» they take a patch of skin from the region where permanent hair grows,
» culture it and spray it on the bald areas, it should grow new hair because
» it’ll have both the stem and progenitor cells.
»
» Of course it’ll probably require extensive wounding or perhaps the
» dermabrasion of the top layer of skin for it to work. Not an inviting
» prospect but if it’s the cure, then I’d be willing to do whatever it
» takes.
»
» Somebody should get in touch with this doctor and ask if it can be applied
» to our purposes (fixing hair loss). So often these researcher types are
» narrowly focused on their treatment, they don’t think about other potential
» applications.

His research is funded by the US military for burn victims/US soldiers, so he’s likely 100% focused on burn victims.

Fixing baldness probably seems like trivial thing by comparison and I’m ok with that … people who are balding have it easy compared to people who have suffered serious burns to their body.

That said, Acell also started off as something intended to be used for military use/healing. Someone could always ask this doctor if the new skin generates hair follicles on it also.


#12

dp


#13

»
» His research is funded by the US military for burn victims/US soldiers, so
» he’s likely 100% focused on burn victims.
»
» Fixing baldness probably seems like trivial thing by comparison and I’m ok
» with that … people who are balding have it easy compared to people who
» have suffered serious burns to their body.
»
» That said, Acell also started off as something intended to be used for
» military use/healing. Someone could always ask this doctor if the new skin
» generates hair follicles on it also.

Exactly, even if it can’t be utilized for re-growing hair, I think it’s wonderful that it can help burn victims. I’ve experienced minor burns as a kid from doing dumb things/accidents and know how painful it can be and how long it takes to heal. So this therapy is a godsend in my opinion.

It’s not the first time I’ve heard of this type of treatment (using stem cells to heal burns), in fact I created a thread about something similar earlier-though the gun is new to me. In the past they indicated that the stem cells do regenerate the entire skin including hair follicles and hair growth.

This is why I think there’s a very good possibility that this doctor’s treatment does the same thing-why wouldn’t it? If it can regrow the skin, why not the hair as well? But yeah, someone would need to confirm this information by contacting the doctor. If he states that it does re-grow hair, then it just needs to be tested for our purposes. This really could be ‘the cure’ for us.


#14

why not someone email the researcher and ask him if it grows hair or if he might experiment to see if he can tweak it to grow hair.

i doubt it does. a hair follicle is like an organ like a heart or lung, skin is more like just a bunch of cells. Even though the skin is supposed to be your largest ‘organ’.

supposing it does grow hair, how would the hair follicle’s orientation be correct when its sprayed on? would not some follicles be facing down, others facing sideways into the scalp, others pointing at different angles upwards. the hair would emerge in all directions.

so ORENTATTION is something to be concerned about.

depth of the hair follicle is another issue. if just a thin sheet of stem cells is sprayed on even if it contains hair follicles, its depth in the skin would be very shallow. how would that work ?

lots of issues and questions.


#15

It seems that its easier for this thing to work when the body needs healing of some short. The stem cells treatments that currently work seems to do wonders for healing like a burn or a wound. There must be a reason for the cells to start working. In baldness there is no reason for them to start a reaction so that explains why they talk about wounding of the scalp and then using stemcells and they have observed hair growth.

It seems that our body doesnt recognize baldness as a reason to heal it self so injecting with the gun or i dont know what the stem cells will have little to no effect.

But to the gun issue at hand it seems that it does what Acell is supposed to do. So i wonder do we really need acell for wound healing or this gun is the future and our own stemcells are enough.

I bet the million dollar question is what happens when a hair transplant surgen will make a strip scar or FUE extractions and will use the gun for the first time. Will the FUE donts dissapear and hair start growing?Will the missing skin from a strip form again with hair? Thats the biggest short term benefit we can expect…

Acell seems not to be able to heal a wound from a strip scar with regeneration of hair…doctors tried or still try it with mixed results we havent seen something groundbreaking yet. will this do any better? It seems to be better funded and it does wonders for burn victims.

I think its difficult because strips and FUE’s go too deep in order to get the roots of the follicles out, we dont know how this works exactly and how deep its healing properties can reach


#16

» It seems that its easier for this thing to work when the body needs healing
» of some short. The stem cells treatments that currently work seems to do
» wonders for healing like a burn or a wound. There must be a reason for the
» cells to start working. In baldness there is no reason for them to start a
» reaction so that explains why they talk about wounding of the scalp and
» then using stemcells and they have observed hair growth.

Maybe we need to set our head on fire.


#17

I emailed Joerg Gerlac concerning hairloss and here is his reply:

“Thank you for your interest in our work.
I would like to comment that the patient was shown around a year after the injury. They say that the wound was healed after 4 days, which is true in the sense that the wound was already dry and the patient could go home without dressing or bandage, but it did not look like a year later in the video. I am very sorry to say that our work does relate only to acute burns. We can not offer treatments for a situation several month after the injury.
This technology is not able to address scars or other conditions like vitiligo, vascular conditions, hair loss or acne.
I am not aware of groups which could offer a solution.
2 papers on all cases are submitted but not yet published by the journals.
Thanks for your mail,
my best greetings, Jorg”


#18

What abour spraying the recipient right after a hair transplant for better healing? Maybe that could help.

We need a hair transplant doctor to call the inventor and give us feedback


#19

I’m sorry for not reading the entire thread. But here is what I’ve read:

Most animals regenerate new skin that includes new hair follicles.
Unfortunately it’s not the same for human skin.


#20

»
» Maybe we need to set our head on fire.
»

LOL, nice pic too. I’m a big fan of the first 2 Alien movies.