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Piroctone Olamine shampoo study


#1

Piroctone Olamine study :

http://pt.wkhealth.com/pt/re/ijco/abstract.00013257-200210000-00001.htm;jsessionid=JF6d22HnPhGH8HTf9xL4ND1Kx9JN1MGgsyYg03TL4Sv89211mzQH!944248918!181195629!8091!-1


#2

» Piroctone Olamine study :
»
»
»
» http://pt.wkhealth.com/pt/re/ijco/abstract.00013257-200210000-00001.htm;jsessionid=JF6d22HnPhGH8HTf9xL4ND1Kx9JN1MGgsyYg03TL4Sv89211mzQH!944248918!181195629!8091!-1

The above link seems to broken. Heres the gist of it:

October 2002, 24:5 > Nudging hair shedding by antidandruff… < Previous | Next >
ARTICLE LINKS:
Fulltext | PDF (197 K)
Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations.

Original Articles

International Journal of Cosmetic Science. 24(5):249-256, October 2002.
Pierard-Franchimont, C.; Goffin, V.; Henry, F.; Uhoda, I.; Braham, C.; Pierard, G. E.
Abstract:
Synopsis: Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis. The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT). Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot. Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, [mu]g cm-2 h-1) was also measured using a Sebumeter®.

The three treatments cleared pruritus and dandruff rapidly. At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%). In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPT shampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface.

© 2002 Blackwell Science Ltd.


#3

am I reading this right? It seems that 1% piroctone olamine is the most effective, even more effective than Keto.

What shampoos contain this ingredient?


#4

http://www.thebodyshop-usa.com/bodyshop/browse/product_detail.jsp?categoryId=cat5260011&productId=prod6270015


#5

» http://www.thebodyshop-usa.com/bodyshop/browse/product_detail.jsp?categoryId=cat5260011&productId=prod6270015

JT
Are you using any other shampoos besides the PTO shampoo?

Regards
Pete


#6

Yes, I rotate and try new things. Currently, I am using Body Shop, Ookisa (worthless) and Origenere (good shampoo). The Ookisa is supposed to be a thickening shampoo, but I see zero evidence of this. I tried the Alpecin recently, but cannot overcome the cheap, euro-cologne smell.


#7

» Yes, I rotate and try new things. Currently, I am using Body Shop, Ookisa
» (worthless) and Origenere (good shampoo). The Ookisa is supposed to be a
» thickening shampoo, but I see zero evidence of this. I tried the Alpecin
» recently, but cannot overcome the cheap, euro-cologne smell.

Aswell as the PTO shampoo.
You may want to try a tea tree shampoo which also contains menthol. This should help to keep your scalp healthy and boost bloodflow.

Regards
Pete


#8

I tend to shy away from mint or menthol-containing shampoos that have “cooling” effects because I read somewhere (I cannot remember where) that they increase TNF. I have found that shampoos containing these ingredients, including Tea Tree Oil, have negative effects on my hair/scalp.


#9

» I tend to shy away from mint or menthol-containing shampoos that have
» “cooling” effects because I read somewhere (I cannot remember where) that
» they increase TNF. I have found that shampoos containing these ingredients,
» including Tea Tree Oil, have negative effects on my hair/scalp.

See my post in the Topical forum ie Elsom Research.

Regards
Pete