» Nizoral Cream - Nizoral Cream Side Effects - Nizoral Cream Information
» Pharmacology: In vitro studies suggest that the antifungal properties of
» ketoconazole may be related to its ability to impair the synthesis of
» ergosterol, a component of fungal and yeast cell membranes. Without the
» availability of this essential sterol, there are morphological alterations
» of the fungal and yeast cell membranes manifested as abnormal membranous
» inclusions between the cell wall and the plasma membrane. The inhibition
» of ergosterol synthesis has been attributed to interference with the
» reactions involved in the removal of the 14 a-methyl group of the
» precursor of ergosterol, lanosterol.
»
»
» Indications: For the topical treatment of tinea pedis, tinea corporis and
» tinea cruris caused by T. rubrum, T. mentagrophytes and E. floccosum ; and
» in the treatment of tinea versicolor (pityriasis) caused by M. furfur (P.
» orbiculare ); and in the treatment of seborrheic dermatitis caused by P.
» ovale ; and in the treatment of cutaneous candidiasis caused by C.
» albicans .
»
» Contraindications: In persons who have shown hypersensitivity to the
» active or excipient ingredients of this formulation.
»
»
» Warnings: Ketoconazole cream should never be employed for the treatment of
» infections of the eye.
»
» To prevent a rebound effect after stopping a prolonged treatment with
» topical corticosteroids, it is recommended to continue applying a mild
» topical corticosteroid in the morning and to apply ketoconazole cream in
» the evening, and to subsequently and gradually withdraw the steroid
» therapy over a period of 2 to 3 weeks.
»
» Precautions: If a reaction suggesting sensitivity or chemical irritation
» should occur, use of ketoconazole cream should be promptly discontinued.
»
» Pregnancy and Lactation: Limited short-term studies in animals and in
» human volunteers on whom limited quantities of ketoconazole cream were
» tested have failed to demonstrate absorption of ketoconazole in detectable
» amounts. Due to the teratogenic nature of the active ingredient,
» ketoconazole, caution should be exercised when ketoconazole cream is
» administered to pregnant or nursing women.
»
» Cross-sensitivity with miconazole and other imidazoles may exist and
» caution is suggested when ketoconazole cream is employed in patients with
» known sensitivities to imidazoles.
»
» Adverse Effects: Short-term studies indicate that ketoconazole cream is
» well tolerated by the skin. During clinical trials, 43 (5.0%) of 867
» patients treated with the cream and 3 (1.8%) of 167 patients treated with
» placebo reported side effects consisting mainly of severe irritation,
» pruritus and stinging. One of the patients treated with ketoconazole cream
» 2% developed a painful allergic reaction (swelling of the foot).
»
» In rare circumstances, allergic local skin phenomena such as contact
» dermatitis have been associated with ketoconazole cream or one of its
» components, namely sodium sulfite or propylene glycol.
»
» Overdose: Symptoms and Treatment: There has been no experience with
» overdosage of ketoconazole cream. Treatment should include general
» supportive measures.
»
»
» Dosage: When clinically warranted, therapy with ketoconazole cream may be
» initiated while results of culture and susceptibility tests are pending.
» Treatment should be adjusted according to the findings.
»
» Ketoconazole cream should be applied to the affected and immediate
» surrounding area in patients with the following conditions: (see Table
» I).
»
» More resistant cases may be treated twice daily depending on patient
» response.
»
» Seborrheic dermatitis: Use twice daily for 4 weeks.
»
» The full course of therapy should be followed to reduce the possibility of
» recurrence. If however, there is no response within the recommended
» treatment period, the diagnosis should be re-evaluated.
»
» The safety of ketoconazole cream has not been established with treatment
» periods exceeding those recommended; therefore, treatment must not exceed
» the recommended duration of therapy indicated above.
»
»
» Supplied: Each g of white, odorless cream contains: ketoconazole 20 mg
» (2%). Nonmedicinal ingredients: cetyl alcohol, isopropyl myristate,
» polysorbate 60, polysorbate 80, propylene glycol, purified water, sodium
» bisulfite, sorbitan monostearate and stearyl alcohol. Tubes of 30 g. Store
» at room temperature, below 25°C. Keep from freezing.
»
» IMPORTANT NOTE: THE FOLLOWING INFORMATION IS INTENDED TO SUPPLEMENT, NOT
» SUBSTITUTE FOR, THE EXPERTISE AND JUDGMENT OF YOUR PHYSICIAN, PHARMACIST
» OR OTHER HEALTHCARE PROFESSIONAL. IT SHOULD NOT BE CONSTRUED TO INDICATE
» THAT USE OF THE DRUG IS SAFE, APPROPRIATE, OR EFFECTIVE FOR YOU. CONSULT
» YOUR HEALTHCARE PROFESSIONAL BEFORE USING THIS DRUG.
Jacobs favorite thing in the world is side effects, he loves them
»
»
» » Nizoral Cream - Nizoral Cream Side Effects - Nizoral Cream Information
» » Pharmacology: In vitro studies suggest that the antifungal properties
» of
» » ketoconazole may be related to its ability to impair the synthesis of
» » ergosterol, a component of fungal and yeast cell membranes. Without the
» » availability of this essential sterol, there are morphological
» alterations
» » of the fungal and yeast cell membranes manifested as abnormal
» membranous
» » inclusions between the cell wall and the plasma membrane. The
» inhibition
» » of ergosterol synthesis has been attributed to interference with the
» » reactions involved in the removal of the 14 a-methyl group of the
» » precursor of ergosterol, lanosterol.
» »
» »
» » Indications: For the topical treatment of tinea pedis, tinea corporis
» and
» » tinea cruris caused by T. rubrum, T. mentagrophytes and E. floccosum ;
» and
» » in the treatment of tinea versicolor (pityriasis) caused by M. furfur
» (P.
» » orbiculare ); and in the treatment of seborrheic dermatitis caused by
» P.
» » ovale ; and in the treatment of cutaneous candidiasis caused by C.
» » albicans .
» »
» » Contraindications: In persons who have shown hypersensitivity to the
» » active or excipient ingredients of this formulation.
» »
» »
» » Warnings: Ketoconazole cream should never be employed for the treatment
» of
» » infections of the eye.
» »
» » To prevent a rebound effect after stopping a prolonged treatment with
» » topical corticosteroids, it is recommended to continue applying a mild
» » topical corticosteroid in the morning and to apply ketoconazole cream
» in
» » the evening, and to subsequently and gradually withdraw the steroid
» » therapy over a period of 2 to 3 weeks.
» »
» » Precautions: If a reaction suggesting sensitivity or chemical
» irritation
» » should occur, use of ketoconazole cream should be promptly
» discontinued.
» »
» » Pregnancy and Lactation: Limited short-term studies in animals and in
» » human volunteers on whom limited quantities of ketoconazole cream were
» » tested have failed to demonstrate absorption of ketoconazole in
» detectable
» » amounts. Due to the teratogenic nature of the active ingredient,
» » ketoconazole, caution should be exercised when ketoconazole cream is
» » administered to pregnant or nursing women.
» »
» » Cross-sensitivity with miconazole and other imidazoles may exist and
» » caution is suggested when ketoconazole cream is employed in patients
» with
» » known sensitivities to imidazoles.
» »
» » Adverse Effects: Short-term studies indicate that ketoconazole cream is
» » well tolerated by the skin. During clinical trials, 43 (5.0%) of 867
» » patients treated with the cream and 3 (1.8%) of 167 patients treated
» with
» » placebo reported side effects consisting mainly of severe irritation,
» » pruritus and stinging. One of the patients treated with ketoconazole
» cream
» » 2% developed a painful allergic reaction (swelling of the foot).
» »
» » In rare circumstances, allergic local skin phenomena such as contact
» » dermatitis have been associated with ketoconazole cream or one of its
» » components, namely sodium sulfite or propylene glycol.
» »
» » Overdose: Symptoms and Treatment: There has been no experience with
» » overdosage of ketoconazole cream. Treatment should include general
» » supportive measures.
» »
» »
» » Dosage: When clinically warranted, therapy with ketoconazole cream may
» be
» » initiated while results of culture and susceptibility tests are
» pending.
» » Treatment should be adjusted according to the findings.
» »
» » Ketoconazole cream should be applied to the affected and immediate
» » surrounding area in patients with the following conditions: (see Table
» » I).
» »
» » More resistant cases may be treated twice daily depending on patient
» » response.
» »
» » Seborrheic dermatitis: Use twice daily for 4 weeks.
» »
» » The full course of therapy should be followed to reduce the possibility
» of
» » recurrence. If however, there is no response within the recommended
» » treatment period, the diagnosis should be re-evaluated.
» »
» » The safety of ketoconazole cream has not been established with
» treatment
» » periods exceeding those recommended; therefore, treatment must not
» exceed
» » the recommended duration of therapy indicated above.
» »
» »
» » Supplied: Each g of white, odorless cream contains: ketoconazole 20 mg
» » (2%). Nonmedicinal ingredients: cetyl alcohol, isopropyl myristate,
» » polysorbate 60, polysorbate 80, propylene glycol, purified water,
» sodium
» » bisulfite, sorbitan monostearate and stearyl alcohol. Tubes of 30 g.
» Store
» » at room temperature, below 25°C. Keep from freezing.
» »
» » IMPORTANT NOTE: THE FOLLOWING INFORMATION IS INTENDED TO SUPPLEMENT,
» NOT
» » SUBSTITUTE FOR, THE EXPERTISE AND JUDGMENT OF YOUR PHYSICIAN,
» PHARMACIST
» » OR OTHER HEALTHCARE PROFESSIONAL. IT SHOULD NOT BE CONSTRUED TO
» INDICATE
» » THAT USE OF THE DRUG IS SAFE, APPROPRIATE, OR EFFECTIVE FOR YOU.
» CONSULT
» » YOUR HEALTHCARE PROFESSIONAL BEFORE USING THIS DRUG.
I tried nizoral cream 2% for the first time last night. I think I used too much because I felt a bit seasick ths morning. However, I also drank a cup of watermelon seed tea which is good for cleaning out your kidneys last night. I’ll take a two day break and try just the nizoral cream in a smaller amount. Hopefully everything will be normal.
» I tried nizoral cream 2% for the first time last night. I think I used too
» much because I felt a bit seasick ths morning. However, I also drank a cup
» of watermelon seed tea which is good for cleaning out your kidneys last
» night. I’ll take a two day break and try just the nizoral cream in a
» smaller amount. Hopefully everything will be normal.
»
» Perry
When I first started my protocol, my head was numb for about 4 weeks; at the end of which new terminal hairs started sprouting.
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