[quote][postedby]Originally Posted by jarjarbinx[/postedby]
A Two-Stepped Culture Method for Efficient Production of Trichogenic Keratinocytes - PubMed
Is this the same technology as SB?
What exactly does this mean?
[postedby]Originally Posted by needhairasap[/postedby]
its just another method to get trichogenic DPs
there is more than 1 way to skin a horse
[postedby]Originally Posted by roger_that[/postedby]
This is not what SB did because first, they’re not converting pluripotent stem cells into anything here.
Second, I don’t exactly agree with Needhairasap, this is not just another way to get trichogenic DP cells. I think it’s more of a way to get trichogenic keratinocytes. They took “high passage” keratinocytes (which would be poorly inductive) and mixed them with inductive DP cells (the inductive DP cells would have to be low-passage or no-passage because high-passage ones would not be inductive). The resulting keratinocytes did not product hair follicles.
But when the same type of keratinocytes were mixed with “follicle DP cells” (which would be low-passage or no-passage, taken straight from the follicle, and thus highly inductive) for 4 days, the resulting keratinocytes regained trichogenic activity.
I think this could be a way of enhancing SB’s work by adding inductive keratinocytes to the mix. Remember hair follicles are really a structure of mixed cell source, and higher quality follicles could probably be created by using several different types of cells, not just DP cells.
Just an idea, but this study may have been “inspired” by SB’s work. Meaning that now more researchers are starting to see that a real cell-based procedure is possible, built on SB’s development, and they want to be part of it in some way, so they’re looking for ways to enhance it.
[postedby]Originally Posted by jarjarbinx[/postedby]
So then this work would still require SB’s technology and of course SB is on indefinite hold.
Well these new keratinocyte technology sounds like it would enhance Sb’s technology and together they would probably be excellent but you’re looking at 5 years minimum until SB gets to market with or without this enhancement. So we still have to look for other ways to regrow hair.[/quote]
even 5 years sounds ridiculously optimistic. have trials even started yet?