Title: METHODS AND COMPOSITIONS FOR INCREASING TRICHOGENIC POTENCY OF DERMAL CELLS
B. Terminal hair induction
Another embodiment provides a method for inducing vellus hair to become terminal hair. Vellus hair is the fine, non-pigmented hair (peach fuzz) that covers the body of children and adults. Terminal hair is developed hair, which is generally longer, coarser, thicker and darker than the shorter and finer vellus hair. As described above there is a morphogenetic switch of terminal to vellus hair follicles in the manifestation of male pattern baldness. In one embodiment, dermal cells with increased trichogenic ability are injected into the skin as described above. The dermal cells are obtained as described above and are typically autologous cells. The cells are injected into or adjacent to vellus hair or vellus hair follicles. Multiple injections of dermal cells may be delivered to an area of skin containing vellus hair to induce as many vellus hair follicles as possible to become terminal hair follicles. It will be appreciated that the number of injections and volume of cells to be injected can be routinely developed by one of skill in the art. In another embodiment, dermal cells with increased trichogenic activity are injected into skin in an amount effective to induce formation of hair follicles and to induce vellus hair follicles to become terminal hair follicles.
Unless defined otherwise, all technical and scientific terms used herein have the same meanings as commonly understood by one of skill in the art to which the disclosed invention belongs. Publications cited herein and the materials for which they are cited are specifically incorporated by reference.
Hopefully ALL their ‘embodiments’ will work as described in their new patent …