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Lgr5 gene might help hair cloning become a reality


#1

Is Lgr5 Gene Discovery a Hair Cloning Breakthrough?
October 21st, 2009

Ok guys i found this, check it out

Q: I heard about the Lgr5 gene being a breakthrough in hair cloning. What’s the latest on that?

A: Many scientists feel that adult stem cells house the answer to cloning (regeneration) of hair follicles. One of the problems of hair cloning, however, is that the cells, once duplicated, “forget” that they are hair follicle cells.

It has recently been discovered that the Lgr5 gene, located in stem cells, appears to contain the “global marker” present in all adult hair follicles. If Lgr5 gene is the “calling card” of the cell, it may carry the cell lineage and shoulder the responsibility of signaling to surrounding stem cells what they are actually supposed to do as they multiply.

Recent experiments have shown that these Lgr5 cells maintain the cells ability to differentiate as hair follicles after many generations of being multiplied in the test tube and, therefore, have the potential of serving as the building blocks of entire new hair follicles. The successful exploitation of this gene would eliminate a major barrier to cloning hair.


#2

» Is Lgr5 Gene Discovery a Hair Cloning Breakthrough?
» October 21st, 2009
»
» Ok guys i found this, check it out
»
» Q: I heard about the Lgr5 gene being a breakthrough in hair cloning.
» What’s the latest on that?
»
» A: Many scientists feel that adult stem cells house the answer to cloning
» (regeneration) of hair follicles. One of the problems of hair cloning,
» however, is that the cells, once duplicated, “forget” that they are hair
» follicle cells.
»
» It has recently been discovered that the Lgr5 gene, located in stem cells,
» appears to contain the “global marker” present in all adult hair follicles.
» If Lgr5 gene is the “calling card” of the cell, it may carry the cell
» lineage and shoulder the responsibility of signaling to surrounding stem
» cells what they are actually supposed to do as they multiply.
»
» Recent experiments have shown that these Lgr5 cells maintain the cells
» ability to differentiate as hair follicles after many generations of being
» multiplied in the test tube and, therefore, have the potential of serving
» as the building blocks of entire new hair follicles. The successful
» exploitation of this gene would eliminate a major barrier to cloning hair.

Interesting find, what’s the source?


#3

» » Is Lgr5 Gene Discovery a Hair Cloning Breakthrough?
» » October 21st, 2009
» »
» » Ok guys i found this, check it out
» »
» » Q: I heard about the Lgr5 gene being a breakthrough in hair cloning.
» » What’s the latest on that?
» »
» » A: Many scientists feel that adult stem cells house the answer to
» cloning
» » (regeneration) of hair follicles. One of the problems of hair cloning,
» » however, is that the cells, once duplicated, “forget” that they are
» hair
» » follicle cells.
» »
» » It has recently been discovered that the Lgr5 gene, located in stem
» cells,
» » appears to contain the “global marker” present in all adult hair
» follicles.
» » If Lgr5 gene is the “calling card” of the cell, it may carry the cell
» » lineage and shoulder the responsibility of signaling to surrounding
» stem
» » cells what they are actually supposed to do as they multiply.
» »
» » Recent experiments have shown that these Lgr5 cells maintain the cells
» » ability to differentiate as hair follicles after many generations of
» being
» » multiplied in the test tube and, therefore, have the potential of
» serving
» » as the building blocks of entire new hair follicles. The successful
» » exploitation of this gene would eliminate a major barrier to cloning
» hair.
»
» Interesting find, what’s the source?

i dont know the source for the actual research but i saw it on bernsteins blog about hair cloning

link


#4

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665733/

it was written in March 2009

it’s only a matter of time before they figure this out…


#5

» http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2665733/
»

nice one vivace


#6

(bumping roger_that’s threads off the bottom of the page)