Home | News | Find a Doctor | Ask a Question | Free

It\'s almost September (ICX)


#1

It’s almost September and I think most of us recall that Intercytex’s full data from the ICX-TRC trial is due sometime in September. Personally I expect either disappointing data or another extended release-date.

Anyone disagree?


#2

» It’s almost September and I think most of us recall that Intercytex’s full
» data from the ICX-TRC trial is due sometime in September. Personally I
» expect either disappointing data or another extended release-date.
»
» Anyone disagree?

Intercytex officialy Won’t be funding trials after phase-II. So it all depends on how good the phase-II went, and if they can find a partner to pursue phase-III trials & then commercialization. As of the moment, Bosley only has priority rights over TRC but that does Not mean that Bosley would be pursuing TRC.

Personally, I really wanted the TRC to just rejuvenate existing follicles, that way we could keep doing it over and over. But the way it looks now, even Dr. Kemp isn’t sure what causes rejuvenation and what causes neogenesis. On top of that the end result is less than acceptable.

Now, I just want someone on these forums to crack Follica procedure…so we can end this misery once and for all and move on with our lives. I’ve already wasted a good part of my life thinking about my NW6 dome…while the world has moved on so quickly.


#3

» Personally, I really wanted the TRC to just rejuvenate existing follicles,

me too, if it worked ant it just rejuvenates existing follicles then it would be perfect; that’s one of the issues I’ve got with follica, the fact that it creates new follicles ( if it really works ) brings to me some questions I can’t answer


#4

On a side note…Intercytex website now lists their Boston office on the contact page. Did they recently open up that office or has it been a while?


#5

» It’s almost September and I think most of us recall that Intercytex’s full
» data from the ICX-TRC trial is due sometime in September. Personally I
» expect either disappointing data or another extended release-date.
»
» Anyone disagree?

its not full data, its 6 months data afaik.


#6

According to some of their figures so far, simple dermabrasion seems to regrow half as much as their drugs. Whether that’s a statement about the weakness of TRC or about the strength of dermabrasion, I don’t know.

But does it really matter?

Either way, it occurs to me that just doing rounds of dermabrasion repeatedly would be lightyears simpler and cheaper than spending another “5-10 years” waiting and praying for ICX-TRC to get on the ball.

If Folica and Acell are both a bust, I might just start dermbrading my balding skin areas every 3-4 months for a couple years and see what I get from it.

It might not look like much at all per round. But unlike even the best Minox and Fin gains, this would probably be REPEATABLE to gradually accrue some real gains.


#7

» » It’s almost September and I think most of us recall that Intercytex’s
» full
» » data from the ICX-TRC trial is due sometime in September. Personally I
» » expect either disappointing data or another extended release-date.
» »
» » Anyone disagree?
»
» its not full data, its 6 months data afaik.

yeah, its not full data.
they will publish partial “results” for the 3 groups injected on Phase II.


#8

»
» If Folica and Acell are both a bust, I might just start dermbrading my
» balding skin areas every 3-4 months for a couple years and see what I get
» from it.
»
» It might not look like much at all per round. But unlike even the best
» Minox and Fin gains, this would probably be REPEATABLE to
» gradually accrue some real gains.

I seriously doubt so. You will not grow any useful hair from dermabrassion alone even if you did it zillion times imho. Especially if you are really bald and not just thin.


#9

» » » It’s almost September and I think most of us recall that Intercytex’s
» » full
» » » data from the ICX-TRC trial is due sometime in September. Personally
» I
» » » expect either disappointing data or another extended release-date.
» » »
» » » Anyone disagree?
» »
» » its not full data, its 6 months data afaik.
»
»
» yeah, its not full data.
» they will publish partial “results” for the 3 groups injected on Phase II.


#10

I seriously doubt so. You will not grow any useful hair from dermabrassion alone even if you did it zillion times imho. Especially if you are really bald and not just thin.

Well, so far two sessions of dermabrasion on the same spot have given me about as much additional hair back right there as the entire year on Fin did.


#11

“Hairsite métete la censura por donde te quepa (nt)”

SD, when you signed up for the forum, you agreed to the forum etiquette set forth in the registration page. If you do not want your comments to be censored, then post responsibly and stop using defamtory comments and unsubstantiated allegations.


#12

» “Hairsite métete la censura por donde te quepa (nt)”
»
» SD, when you signed up for the forum, you agreed to the forum etiquette
» set forth in the registration page. If you do not want your comments to be
» censored, then post responsibly and stop using defamtory comments and
» unsubstantiated allegations.

Unsubstantiated allegations?? Oh, well.
If I say: ICX WILL CURE US!! would you censor my message? That is an unsubstantiated allegation, isn’t it? Then, you should delete this message too!! But how come only the negative allegations are deleted?

Hairsite, this is not a TV show on prime-time with millions of watchers.
This is not a diplomat’s forum.
At this point, to express disenchantment with ICX, using sarcasm, is a totally normal reaction. I don’t remember what I exactly posted, but nothing specially strong as to be censored in an internet forum.
As far as I know, this forum is not associated with ICX, so I don’t understand
why we have to be so nice with them.

I was positive with ICX, when I thought there were reasons to be positive, and now I am negative because I think there are reasons to be negative.
Not long ago, James Bond accused me of being biased in favour of ICX, and somehow having an agenda for them. And I told him: I have no agenda. I was nice with Gho and Bazan at the begining, until I found that they were manipulating us. And I will do the same with ICX.

Still, until September’s report, I don’t want to talk much about ICX. My post was just 2/3 lines long.


#13

» Still, until September’s report, I don’t want to talk much about ICX. My
» post was just 2/3 lines long.

By the way, correct me if I am wrong, Intercytex has never said they would release the full phase II trial data in September. The September timeline was quoted strictly in reference to the interim financial reporting requirement stipulated by the stock exchange in the UK. The most that they would disclose is probably a brief paragraph here or there about the trial results, much like what we have read back in March.

I hope I am wrong, but please don’t get your hopes high about a full disclosure for phase II trial data.


#14

ICX-TRC clinical and commercial development

Phase I clinical trials (safety) have been completed in seven volunteers at a single UK transplant centre. No safety issues have arisen and five out of seven patients have shown increased hair numbers.

The treatment phase of a Phase II trial, being conducted by Dr Bessam Farjo in Manchester, to optimise the delivery of the DP cells, has been completed.

In this study, hair counts were obtained by shaving and photographing a small section of scalp, injecting it and then applying a specialised image analysis system to provide a total hair count. All 19 subjects in the trial have now been treated using a range of injection and scalp pre-stimulation techniques; the first six subjects were injected without stimulation of the scalp. In the remaining 13 the resident hair producing (epithelial) cells were stimulated at the time of delivery of the DP cells.

11 subjects have now passed the 24-week time point since treatment and specialised image analysis at this time point showed:

· Of the group of six patients without stimulation of the scalp, three had an increased hair count and two had a reduced hair count; one has been lost to follow-up.

· Of the five subjects with pre-treatment scalp stimulation, all had increased hair count at 12 weeks and the three who were evaluable at 24 weeks all had an increased hair count at that time point.

These data are consistent with the earlier data reported last September and the hypothesis that new hair production is improved by pre-stimulation of the scalp, leading to an interaction between the injected cells and the resident hair producing cells.

24 week data on all subjects in the trial will be available in September 2008 and at the end of the trial, photographic data will be analysed from a much larger area of treated scalp on all subjects at 48 weeks.


#15

» 24 week data on all subjects in the trial will be available in
» September 2008 and at the end of the trial, photographic data will
» be analysed from a much larger area of treated scalp on all subjects at 48
» weeks.

It says it will be AVAILABLE but does it mean that they will actually release or disclose the data?

It’s one thing being AVAILABLE and a totally different thing whether the data will be DISCLOSED or RELEASED to the public.

Like I said, I hope I am wrong.


#16

indeed, the September report is just another update, but it will include data of the full set of trialists (3 groups). The final results will have to be analyzed and then they will publish results next year. And we don’t know what will they publish.

I am just hoping that the September report is not like the previous ones, i.e, something obscure and evasive.
If the results are bad, I would like to know them as they are.


#17

» » 24 week data on all subjects in the trial will be available
» in
» » September 2008 and at the end of the trial, photographic data
» will
» » be analysed from a much larger area of treated scalp on all subjects at
» 48
» » weeks.
»
» It says it will be AVAILABLE but does it mean that they will
» actually release or disclose the data?
»
» It’s one thing being AVAILABLE and a totally different thing
» whether the data will be DISCLOSED or RELEASED to the public.
»
»
» Like I said, I hope I am wrong.

Yes, the September is just another report, and they will post something, as usual, just a few lines in the report. I hope they mention the 3rd group of trialists, to see if the 3rd formulation is better than the others.


#18

» indeed, the September report is just another update, but it will include
» data of the full set of trialists (3 groups). The final results will have
» to be analyzed and then they will publish results next year. And we don’t
» know what will they publish.

Where did they say they would disclose “data of the full set of trialists (3 groups)” in September?

»
» I am just hoping that the September report is not like the previous ones,
» i.e, something obscure and evasive.
» If the results are bad, I would like to know them as they are.

I speculate that it will be very much like the March report unless they have officially signed up a partner for the phase III trial.


#19

By the September report, they will have data of the full set of trialists.
How much of it will be mentioned in the report is another matter.
In the past reports, they always provided basic information on all the available trialists.

So I expect this time to be the same.
They will mention something, but I am not sure if they will provide numbers.
At the beginning, they provided numbers. Then percentages. And in the last report, not even numbers, if I recall.

If they don’t provide numbers in this September report, then I think we can forget about TRC.

»
» Where did they say they would disclose “data of the full set of
» trialists (3 groups)”
in September?
»
» »
» » I am just hoping that the September report is not like the previous
» ones,
» » i.e, something obscure and evasive.
» » If the results are bad, I would like to know them as they are.
»
» I speculate that it will be very much like the March report unless they
» have officially signed up a partner for the phase III trial.


#20

» » “Hairsite métete la censura por donde te quepa (nt)”
» »
» » SD, when you signed up for the forum, you agreed to the forum etiquette
» » set forth in the registration page. If you do not want your comments to
» be
» » censored, then post responsibly and stop using defamtory comments and
» » unsubstantiated allegations.
»
» Unsubstantiated allegations?? Oh, well.
» If I say: ICX WILL CURE US!! would you censor my message? That is an
» unsubstantiated allegation, isn’t it? Then, you should delete this message
» too!! But how come only the negative allegations are deleted?
»
» Hairsite, this is not a TV show on prime-time with millions of watchers.
» This is not a diplomat’s forum.
» At this point, to express disenchantment with ICX, using sarcasm, is a
» totally normal reaction. I don’t remember what I exactly posted, but
» nothing specially strong as to be censored in an internet forum.
» As far as I know, this forum is not associated with ICX, so I don’t
» understand
» why we have to be so nice with them.
»
» I was positive with ICX, when I thought there were reasons to be positive,
» and now I am negative because I think there are reasons to be negative.
» Not long ago, James Bond accused me of being biased in favour of ICX, and
» somehow having an agenda for them. And I told him: I have no agenda. I was
» nice with Gho and Bazan at the begining, until I found that they were
» manipulating us. And I will do the same with ICX.
»
» Still, until September’s report, I don’t want to talk much about ICX. My
» post was just 2/3 lines long.

Back when ICX released “data” and claimed that they were looking for a partner, I called a spade a spade in saying it was obvious that their protocol had failed. Hairsite deleted all my comments, then started saying I was slandering ICX. It was laughable.

Why can we say whatever we want about Acell or Follica, but ICX gets special protection? Hairsite must own some stock.