» Hi hairtech,
» That would be very generous of you. I think many who follow HM would be
» interested in Washenik’s comments as in fact he is a genuine insider. In
» addition, his comments on the one-cell approach would be useful inasmuch
» this is the approach being undertaken by Intercytex.
» All the best,
» » Boston,
» » I tell you what, I am going to get his lecture and type it in when for
» » you.
Mention of the “one cell approach,” “two cell approach” etc. is a very abstract way of looking at a very technical subject. In truth, no HM protocol will work that uses only one or two types of cells. What is meant by this terminology is whether an epithelial cell based solution is used, a mesenchymal cell based solution is used, or a mixture of epithelial and mesencymal cells is used. IOW, the main type of cell is the base, but many other cell types need to be present in order to get the follicle to grow.
You need the mesencymal cells and the epithelial cells to communicate, so with the “one cell approach,” ICX injects a mesenchymal based solution into the skin and relies on the existing epithelial cells to complete the package. Gho does the opposite and injects epithelial cells and relies on the existing mesencymal cells. So far, I only know of animal experiments that use both types of cells together due to the problems this technique represents. Although using both kinds in culture keeps the cells extremely viable, other problems result, so it is not being used in humans yet.
But it gets even deeper than this, because technically, if you are stimuating as opposed to creating new follicles, you don’t really have to think about the other cell type. This is because you are targeting the follicle bases in an attempt to get them to uptake healthy cells that allow the follicle to begin signaling properly again. I’m speaking strictly of injecting dermal cells so that the follicles’ migration pathways uptake them into the papilla. Once present, the newly migrated cells can begin to communicate with the surrounding cells and get the follicle to grow normally again. The dermal cells orchestrate the entire process, but get whacked out when DHT loading occurs. So the goal is to simply replace them.
There are lots of ways to go about HM, and each way has its strengths and weaknesses.