I just heard two interviews a certain radio show host had with Replicel and Histogen people.
Both interviews are very recent (one made just a couple days ago).
Based on those interviews, both replicel and histogen sound promising. Possibly replicel hoping to be approved for treatment and released in Japan possibly as soon as 3 years.
One of the reasons, or maybe the only reason, for a what seems a poor response to one injection, seems
to have to do with the injection coinciding with a given hair follicle being in
a certain stage of its growth cycle.
So, since only a percentage of follicles are in that stage at any given time, only those follicles would respond to an injection.
This means that repeated injections spaced weeks or month apart, should catch more follicles in the right stage, and so benefit those.
Seems the reason both repplicel and histogen went dark on us, was because of the lawsuit that histogen only won in erly 2014–no one would invest in funding them when there was uncertainty over whether or not they owned the patent. In the case of replicel, the culture medium they were using was discontinued by the manufacturer. It took some time for them to get the recipe from the company that discontinued it, and then they stil had to experiment with getting the medium custom made.
So both replicel and histogen are back on track, and they both sound like very promising treatments (not cures).
But I think it’s most likely to help people who still have at least vellus hairs. I’m not sure eithr treatment would resurrect totally dead follicles. But I am not certain about that.
Replicel, for example, would probably have to be injected every few years, as the bald area widens, to get those follicles that quit growing at the periphery of horseshoe bald area as the area expands. No big deal as far as I’m concerned.
Both sound great and might even be able to benefit me.
If the next trials go well, Replicel might be available in Japan in 2 or 3 years. I think it was Histogen that is also exploring release in Japan, Mexico, and Turkey, for medical tourism. This is because the USA takes longer because of regulations.
One picture of a guy in the trial under Histogen trials conducted in the USA under Ziering, showed pretty impressive results in an overhead before and after photo. The guy was still in the early stage of balding, but about a third of his scalp was visable through his hair. After the trial, maybe only 5 or 10% of his scalp was visible.
All exciting stuff.