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If you could only use ONE topical AA, which would it be?


#1

I am a seborhea (sp) eczema aggravated scalp hair loss person. So I have to use as few topicals and wash my hair twice per day, but it works (for keeping the flakes and aggravation down. But my question is, since I can’t have much buildup on my scalp, I already use minox foam, but what topical anti androgen should I use - spiro, azelaic acid, remox, flutamide - which is the best in your alls opinion - I may not be a frequent poster, but I was 5-6 years ago.
Thanks
louis


#2

» I am a seborhea (sp) eczema aggravated scalp hair loss person. So I have to
» use as few topicals and wash my hair twice per day, but it works (for
» keeping the flakes and aggravation down. But my question is, since I can’t
» have much buildup on my scalp, I already use minox foam, but what topical
» anti androgen should I use - spiro, azelaic acid, remox, flutamide - which
» is the best in your alls opinion - I may not be a frequent poster, but I
» was 5-6 years ago.
» Thanks
» louis

how about ketoconazole?


#3

yeah, i use keto, i wash with 2% nizoral.


#4

I feel 2% ketaconazole is the best option.

Zinc and piroctone added to it can improve the outcome ====

Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations.

Int J Cosmet Sci. 2002 Oct;24(5):249-56

Hair shedding and hair thinning have been reported to be affected by dandruff and seborrhoeic dermatitis.

The present study was conducted in 150 men presenting with telogen effluvium related to androgenic alopecia associated with dandruff. They were randomly allocated to three groups receiving each one of the three shampoos in the market containing either 1% ketoconazole (KTZ), 1% piroctone olamine (PTO) or 1% zinc pyrithione (ZPT).

Shampoos had to be used 2-3 times a week for 6 months. Hair shedding during shampoo was evaluated semiquantitatively. Hair density on the vertex was evaluated on photographs using a Dermaphot.

Trichograms were used for determining the anagen hair percentage and the mean proximal hair shaft diameter using computerized image analysis. The sebum excretion rate (SER, mug cm(-2) h(-1)) was also measured using a Sebumeter(®).

The three treatments cleared pruritus and dandruff rapidly. At end point, hair density was unchanged, although hair shedding was decreased (KTZ: -17.3%, PTO: -16.5%, ZPT: -10.1%) and the anagen hair percentage was increased (KTZ: 4.9%, PTO: 7.9%, ZPT: 6.8%). The effect on the mean hair shaft diameter was contrasted between the three groups of volunteers (KTZ: 5.4%, PTO: 7.7%, ZPT: -2.2%).

In conclusion, telogen effluvium was controlled by KTZ, PTO and ZPT shampoos at 1% concentration. In addition, KTZ and PTO increased the mean hair shaft thickness while discretely decreasing the sebum output at the skin surface.


#5

I found spiro to be DETRIMENTAL (=hairloss induceruntil I stopped it, 3months into the treatment).
Keto: ditto (in my case)
Azelaic:said to be weak.
flutamide: ?
remox= mainly minox, isn’t it?
I have modest results with revivogen.


#6

I have read that before hairsite, but do you think that the 2% keto shampoo isn’t enough, that i should use it as a topical instead of the shampoo??
louis