» I am not as confident in the posted results for the same reasons that I
» have been skeptical about its near term release. First, the lack of
» consistency of regrowth is concerning to me, if one part of your head
» responds as they wish, but another does not, then you might have alfala
» sprouts arising without any level of consistency. that would look really
» weird and in my mind, athough the hairs that actually grew back would be
» cosmetically acceptable, the overall solution would not be as you would
» now have a balding pattern that is atypical of MPB. I am particularly
» interested in the pattern of hairs regrown, rather than the number that
» actually regrew hair. even the 103%er could have a really weird pattern of
» regrowth, so more is needed to truly understand.
I also seriously doubt the 2008 commercial release will come to pass–any chance of that ever happening was just an optimistic best-case-scenario, IMHO. I don’t see sectionalized “clumping” of growth as an issue though. If I had to guess, based on everything I’ve read by the more knowledgeable posters here, the areas that are less likely to respond are the areas that have been bald the longest, so you’d still have a pattern of loss in the areas that didn’t respond.
Which leads to another point. These interim results are based on just one session. It’s been suggested by a number of posters (including, but not limited to TheGame) that repeat procedures would likely be necessary, depending on how long a person has been bald. If, worst case scenario, one session yields 13% regrowth, and you go back 3-4 more times, you’ll have enough for a cosmetically acceptable appearing full head of hair (yeah, I know–it’ll cost more). This supposes that repeat procedures will produce additional growth at the same rate as the first time.
If I had to guess (which is all I am, or pretty much anyone here is doing right now), I’d say the 105%-er was the youngest guy in the batch.
» secondly, the second cohort had addtional substances injected in order to
» achieve better results. if ICX determines that anything other than one’s
» own cells are necessary to achieve success, then they are back to Phase I
» because foreign substances were not part of that evaluation and it would
» need to be reevaluated for safety.
Good point. I mentioned they added epithelial cells–they actually stimulated them (no idea how) in the second cohort, but probably by adding something to the solution. I was under the impression, however, that they had to test something other than one’s own cells in Phase I. I thought this was the whole point of why having a propriety step in the process required them to go through this testing, which would not have been necessary but for the fact that the proprietary step in the process involved a foreign substance. So as long as they didn’t introduce any new foreign substances into the procedure, they would be fine testing out whatever kind of autologous cells they needed to.
» one more thing, as far as the term “commercialization”, I believe they are
» really talking about a large scale Phase III and not openly available to
» the public.
» HM is proven as science, but many of its detractors properly point out
» that noone really knows who it will work on, how effective it will be and
» cannot guarantee a “cosmetically acceptable solution”
I agree to an extent, but I think the fact that a relatively small sampling pool has been used by ICX inidicates that there is a very high level of predictability among human beings with respect to consistency of cellular properties.
» all and all, I still have hope, but I must say that these results cannot
» be viewed as positive and at the very least, the timeline has taken a
» pretty big hit
I don’t think the results are bad at all. Remember, the second cohort figures are based on a twelve-week interval, which was a vast improvement over the first cohort. Guys who have entire follicles transplanted need up to 12 months to fully appreciate their results. The fact that timeline got pushed back again is annoying, but who is really surprised about that? We’re all on notice about delays–it’d be a huge miscalculation not to expect them at this point…