» you are wasting your money. even if it works (a big if) there is little
» chance that it is going to make it to market before they run out of money.
» histogens product uses embryonic stem cells which have yet to approved by
» the fda. you have to believe that if histogen is going to be the first
» embryonic stem cell therapy the fda is going to require them to present a
» TON of data with LARGE, LONG safety trials.
» Also a kid in isreal used embryonic stem cells to treat some disease and
» now he has cancer. So this is going to get a TON of scrutiny.
» I wouldn’t use it and wouldn’t want to rub it on my head.
From Histogens site,
Histogen, launched in 2007, seeks to redefine regenerative medicine by developing a series of high value products that do not contain embryonic stem cells or animal components. Through Histogen’s proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the Company has developed its rich product portfolio. Histogen has two product families - ExceltrixTM, Histogen’s human Extracellular Matrix (ECM) and ReGenica, Histogen’s proprietary liquid formula.
The actual first embryonic stem cell trial is being held by a company called Geron who are looking for a treatment for spinal injury.
You are right about fetal (Not embryonic) stem cells causing cancerous tumors in some cases, this is because the injected cells grow out of control.
Here is an article about the case you are talking about
"Then he was diagnosed with a brain tumor in 2005. That tumor, it turns out, grew out of the stem cells, obtained from at least two aborted fetuses, used in his brain.
The tumor was benign, doctors safely removed it, and it has gradually been growing back since the surgery. But this is the first-known case of a brain tumor caused by a brain stem cell therapy, according to the report—a phenomenon scientists have predicted in the pages of Scientific American and elsewhere. The theory is that because these stem cells are fetal cells, they are designed to proliferate and give rise to new tissue, which means they have the potential to produce tumors. The case, write the authors of this week’s case study, should serve as a warning that more research is needed to gauge the safety of these novel therapies.
Other stem cell experts echo their concerns and worry that scientists don’t yet understand exactly how stem cells used in such treatments behave once inside the body. Treating neurological disorders with stem cells from fetal brains is a “great scientific goal to pursue,” but there is simply not enough evidence from animal studies, let alone human studies, to prove it is safe or effective for treating these diseases in children, says Sean Savitz, a neurologist at the University of Texas Medical School at Houston.
Savitz has just begun enrolling patients in a study on treating adult stroke victims with their own—adult—stem cells. The intent of the boy’s treatment must have been to use these fetal stem cells to regenerate tissue lost in certain areas of the brain, Savitz speculates, but he adds, “we don’t have a full understanding of how [brainlike] stem cells can generate different cells in the brain.”
Savitz says that the stem cells used in his trial are not likely to cause cancer because they are adult cells taken from bone marrow that die once they have accomplished their mission of repairing brain tissue.
Again, it was FETAL stem cells NOT EMBRYONIC that caused the tumor, it is still unknown if embryonic stem cells can cause cancer but they have been shown to KILL cancer cells.
Here is an interesting recent article on stem cells and cancer,