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How do we know acell will work on humans?


#1

it seems to me we really don’t know much about how acell works, even from a practical point of view… like, what exactly is it doing?

also, some have said acell was tested on human skin grafted onto dogs or mice - really? where is the photographic evidence that it worked? can we see some photos of this human hair growing, please???

another question that nobody’s brought up here - and before you all want to lynch me, just let me say it’s another PRACTICAL issue that may have eluded lots of people, even the experimenters:

what if acell is just stretching the skin on those dogs? what if it’s just encouraging the skin to stretch and close the wound, without really creating new skin or hair (fur)?

in other words, what if the results are just sort of a visual trick? we see wounds being closed with skin and fur, but how do we know the wound isn’t just shrinking and pulling the existing healthy skin around it, to close the wound?

have they actually confirmed that this is all BRAND NEW skin and fur? have they tagged some of the fur on the circumference of the fresh wound - maybe put a string or tape or clip around some of the hair - and then watch to see if the same hair isn’t just moving as the skin stretches over the wound?

seems to me that if new hair was actually being created, the fur on the edges of the wound would always look like small, new vellus hairs and then gradually mature into thicker terminal hairs.

but to me, it LOOKS like what we’re seeing is that the hairs on the edges of the wound always look the same - like long, thick, terminal hair or fur.

i admit i may be totally wrong or off base on this, maybe someone with more knowledge can shed some light on it, but it is a question worth asking…


#2

They are good questions. Why don’t you call the company and ask them those questions. Or you could try to contact Dr. Jones (he is the one doctor who has announced trials with Acell although I know of a few more) and see if they will discuss those issues with you. Otherwise, we will just have to wait to see what happens.


#3

» also, some have said acell was tested on human skin grafted onto dogs or
» mice

I think you meant follica


#4

I guess the answer is. We don’t.

I was fairly optimistic, now I start to see reasons (if the information is true in the other thread) that show it easily can fail to grow any hair in humans.


#5

» I guess the answer is. We don’t.
»
» I was fairly optimistic, now I start to see reasons (if the information is
» true in the other thread) that show it easily can fail to grow any hair in
» humans.

Hi, debris.

What other information are you talking about?

Which other thread?


#6

We shall know the answer soon from ACELL.


#7

» » I guess the answer is. We don’t.
» »
» » I was fairly optimistic, now I start to see reasons (if the information
» is
» » true in the other thread) that show it easily can fail to grow any hair
» in
» » humans.
»
» hi, debris.
»
» what other information are you talking about?
»
» which other thread?

The “troll” fckhrls found out on the net that:

a) regrowing fingertips is pretty common ability of humans. You dont need acell to be able to do that.

b) animal wounds heal with skin and fur … once again, no acell necessary.

I started a new thread and links to both are here now:

http://www.hairsite.com/hair-loss/board_entry-id-35592-page-0-order-last_answer-descasc-DESC-category-1.html


#8

» it seems to me we really don’t know much about how acell works, even from a
» practical point of view… like, what exactly is it doing?
»
» also, some have said acell was tested on human skin grafted onto dogs or
» mice - really? where is the photographic evidence that it worked? can we
» see some photos of this human hair growing, please???
»
» another question that nobody’s brought up here - and before you all want
» to lynch me, just let me say it’s another PRACTICAL issue that may have
» eluded lots of people, even the experimenters:
»
» what if acell is just stretching the skin on those dogs? what if it’s
» just encouraging the skin to stretch and close the wound, without really
» creating new skin or hair (fur)?
»
» in other words, what if the results are just sort of a visual trick? we
» see wounds being closed with skin and fur, but how do we know the wound
» isn’t just shrinking and pulling the existing healthy skin around it, to
» close the wound?
»
» have they actually confirmed that this is all BRAND NEW skin and fur? have
» they tagged some of the fur on the circumference of the fresh wound - maybe
» put a string or tape or clip around some of the hair - and then watch to
» see if the same hair isn’t just moving as the skin stretches over the
» wound?
»
» seems to me that if new hair was actually being created, the fur on the
» edges of the wound would always look like small, new vellus hairs and then
» gradually mature into thicker terminal hairs.
»
» but to me, it LOOKS like what we’re seeing is that the hairs on the edges
» of the wound always look the same - like long, thick, terminal hair or fur.
»
»
» i admit i may be totally wrong or off base on this, maybe someone with
» more knowledge can shed some light on it, but it is a question worth
» asking…

Just want to ask you a question: how are you going to fit a skin stretching contraption on the animal for 24x7 to stretch the 5x5 gaping wound?

Can you explain this problem about the dolphin too?


#9

» » it seems to me we really don’t know much about how acell works, even from
» a
» » practical point of view… like, what exactly is it doing?
» »
» » also, some have said acell was tested on human skin grafted onto dogs
» or
» » mice - really? where is the photographic evidence that it worked? can
» we
» » see some photos of this human hair growing, please???
» »
» » another question that nobody’s brought up here - and before you all
» want
» » to lynch me, just let me say it’s another PRACTICAL issue that may have
» » eluded lots of people, even the experimenters:
» »
» » what if acell is just stretching the skin on those dogs? what if
» it’s
» » just encouraging the skin to stretch and close the wound, without
» really
» » creating new skin or hair (fur)?
»
» » in other words, what if the results are just sort of a visual trick? we
» » see wounds being closed with skin and fur, but how do we know the wound
» » isn’t just shrinking and pulling the existing healthy skin around it,
» to
» » close the wound?
» »
» » have they actually confirmed that this is all BRAND NEW skin and fur?
» have
» » they tagged some of the fur on the circumference of the fresh wound -
» maybe
» » put a string or tape or clip around some of the hair - and then watch
» to
» » see if the same hair isn’t just moving as the skin stretches over the
» » wound?
» »
» » seems to me that if new hair was actually being created, the fur on the
» » edges of the wound would always look like small, new vellus hairs and
» then
» » gradually mature into thicker terminal hairs.
» »
» » but to me, it LOOKS like what we’re seeing is that the hairs on the
» edges
» » of the wound always look the same - like long, thick, terminal hair or
» fur.
» »
» »
» » i admit i may be totally wrong or off base on this, maybe someone with
» » more knowledge can shed some light on it, but it is a question worth
» » asking…
»
» Just want to ask you a question: how are you going to fit a skin
» stretching contraption on the animal for 24x7 to stretch the 5x5 gaping
» wound?
»
» Can you explain this problem about the dolphin too?

skin stretching contraption? who needs a skin stretching contraption?

i was speculating that the acell formulation ITSELF might cause the skin to stretch - not using any contraption at all.


#10

I think it takes a bigger leap of faith to believe that the skin stretches such large distances during healing by itself, than to just believe it’s regenerating.


#11

We don’t know but that’s why we r having trials.
Throughout history doctors have not known the outcome of their trials/ experiments yet some of these trials/experiments have gone on 2 advance the well being of mankind.

I look at it this way,surgery as a solution 2 my hair loss was a complete failure,in fact it made me look & feel even worse.As far as I am concerned, at this point in time there is no solution 2 my problem.If ACELL fails then I haven’t lost anything, my life will just continue 2 suck.
But if it works then I have so much 2 gain.
We wont know unless we try.Either we do nothing/we do something.
In time we will know all.


#12

» We don’t know but that’s why we r having trials.
» Throughout history doctors have not known the outcome of their trials/
» experiments yet some of these trials/experiments have gone on 2 advance the
» well being of mankind.
»
» I look at it this way,surgery as a solution 2 my hair loss was a complete
» failure,in fact it made me look & feel even worse.As far as I am concerned,
» at this point in time there is no solution 2 my problem.If ACELL fails then
» I haven’t lost anything, my life will just continue 2 suck.
» But if it works then I have so much 2 gain.
» We wont know unless we try.Either we do nothing/we do something.
» In time we will know all.

I Doubt even one doc will be willing to leave a big gaping wound upen on a hair transplant and sprinkle acell on there like pixie dust


#13

» » We don’t know but that’s why we r having trials.
» » Throughout history doctors have not known the outcome of their trials/
» » experiments yet some of these trials/experiments have gone on 2 advance
» the
» » well being of mankind.
» »
» » I look at it this way,surgery as a solution 2 my hair loss was a
» complete
» » failure,in fact it made me look & feel even worse.As far as I am
» concerned,
» » at this point in time there is no solution 2 my problem.If ACELL fails
» then
» » I haven’t lost anything, my life will just continue 2 suck.
» » But if it works then I have so much 2 gain.
» » We wont know unless we try.Either we do nothing/we do something.
» » In time we will know all.
»
»
» I Doubt even one doc will be willing to leave a big gaping wound upen on a
» hair transplant and sprinkle acell on there like pixie dust

if acell works like some ppl here say its gonna work, then theoretically a doctor could just cut a gigantic wound over the top of the scalp - cut out the entire balding area in one piece - and then sprinkle acell on the wound… and just watch the new hair grow in from the sides and back of the scalp.

somehow i just don’t think that’ll work, though…


#14

Aww, come on.

You guys know as well as I do that it’ll be very practical to use on FUE extraction wounds if it turns out to regrow hair.

And if it doesn’t regrow hair, it could still easily turn out to be a huge benefit to strip-scarring just in terms of improving (sutured) wounds.


#15

»
» I Doubt even one doc will be willing to leave a big gaping wound upen on a
» hair transplant and sprinkle acell on there like pixie dust

1st of all,Dr Jones is not testing this 4 a baldness cure or 4 a way 2 close strip wounds.He is testing this 2 see if he can repair pre existing scars.

Dr Jones is going to test a small area.If that works then he will probably progress 2 larger & larger wounds.4 guys like me who have massive strip scarring in the donor area,we can have multiple small procedures rather than having an entire strip scar wounded & repaired in 1 go.

Dr Jones is not the only person experimenting w/ pixie dust.There r other docs trying a range of different things so MAYBE someone will get it right? MAYBE.

Mike,If u didn’t try the naturals u wouldn’t have been able 2 hold onto ur hair,right ? What did u have 2 lose by trying? Nothing! What did u have 2 gain? PLENTY! U rolled the dice & won,Jones is merely rolling the dice as well.


#16

» Dr Jones is not the only person experimenting w/ pixie dust.There r other
» docs trying a range of different things so MAYBE someone will get it right?
» MAYBE.
»

Has anyone heard from any other dr. regarding ACELL? I thought only Dr. Jones, so far, has committed to testing ACELL.


#17

He is the only one on this board that is publicly testing it…others are trying it as well


#18

» »
» » I Doubt even one doc will be willing to leave a big gaping wound upen on
» a
» » hair transplant and sprinkle acell on there like pixie dust
»
» 1st of all,Dr Jones is not testing this 4 a baldness cure or 4 a way 2
» close strip wounds.He is testing this 2 see if he can repair pre existing
» scars.
»
» Dr Jones is going to test a small area.If that works then he will probably
» progress 2 larger & larger wounds.4 guys like me who have massive strip
» scarring in the donor area,we can have multiple small procedures rather
» than having an entire strip scar wounded & repaired in 1 go.
»
» Dr Jones is not the only person experimenting w/ pixie dust.There r other
» docs trying a range of different things so MAYBE someone will get it right?
» MAYBE.
»
» Mike,If u didn’t try the naturals u wouldn’t have been able 2 hold onto ur
» hair,right ? What did u have 2 lose by trying? Nothing! What did u have 2
» gain? PLENTY! U rolled the dice & won,Jones is merely rolling the dice as
» well.

i am not saying that the acell couldnt work or that we skeptics hope it does not

but what we are saying is , if its never even been tested in humans, why is it worth such hype?


#19

I dont think anybody is trying to hype up Acell…I guess some people are going to get extremely excited at the possibility of and form of HM …Which isnt a good idea…I certanly dont want anybody to get there hopes up to be let down again…although its hard not to to get excited about it at all…and I guess you could say they are doing the human testing now…Im excited that they are testing something now rather than the old…“keep your mouth shut…we arent gonna tell you anything…and wait 5 years”…we should know something in months


#20

» it seems to me we really don’t know much about how acell works, even from a
» practical point of view… like, what exactly is it doing?
»
» also, some have said acell was tested on human skin grafted onto dogs or
» mice - really? where is the photographic evidence that it worked? can we
» see some photos of this human hair growing, please???
»
» another question that nobody’s brought up here - and before you all want
» to lynch me, just let me say it’s another PRACTICAL issue that may have
» eluded lots of people, even the experimenters:
»
» what if acell is just stretching the skin on those dogs? what if it’s
» just encouraging the skin to stretch and close the wound, without really
» creating new skin or hair (fur)?
»
» in other words, what if the results are just sort of a visual trick? we
» see wounds being closed with skin and fur, but how do we know the wound
» isn’t just shrinking and pulling the existing healthy skin around it, to
» close the wound?
»
» have they actually confirmed that this is all BRAND NEW skin and fur? have
» they tagged some of the fur on the circumference of the fresh wound - maybe
» put a string or tape or clip around some of the hair - and then watch to
» see if the same hair isn’t just moving as the skin stretches over the
» wound?
»
» seems to me that if new hair was actually being created, the fur on the
» edges of the wound would always look like small, new vellus hairs and then
» gradually mature into thicker terminal hairs.
»
» but to me, it LOOKS like what we’re seeing is that the hairs on the edges
» of the wound always look the same - like long, thick, terminal hair or fur.
»
»
» i admit i may be totally wrong or off base on this, maybe someone with
» more knowledge can shed some light on it, but it is a question worth
» asking…

I raised the same questions too earlier in the forum, there is not a lot of information on human trials and roughly how many human patients have been treated with this Acell matrix. I couldn’t even find any FDA documentation about this product.