Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit “Shelves” As

Stem cell; cell based hair therapy
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Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit “Shelves” As Soon As 2013 - Dated 17th November

Changing the lives of hair loss sufferers forever: Histogen Inc. might be doing just that, and sooner than many in the hair loss industry thought.

Watch exclusive American Hair Loss Association Video Q&A of Dr. Gail Naughton, Ph.D. as she answers user questions concerning Histogen’s Hair Stimulating Complex’s availability, and how it might be used to effectively treat hair loss in the very near future.

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cool, hope for the best !

3

I’m confused. They did a very small cohort, and now they’re talking about a commercial product? They haven’t even really established efficacy, much less safety. And what about their legal troubles? Have those been quashed?

4

regulatory permissions in asia countries, for usa, one year later. She says that in some cases a patient will need a second injections, after 3 or 6 months, but she say the procedure will treat large alopecia areas.

She told something about 2010, in asia, but i haven’t understand what. Maybe the start of another phase of study before commercialize!

5

» I’m confused. They did a very small cohort, and now they’re talking about
» a commercial product? They haven’t even really established efficacy, much
» less safety. And what about their legal troubles? Have those been
» quashed?

She’s pretty much just assuming efficacy at this point. They are going to start larger scaled clinical trials in Singapore early 2010. I think that study will be determine the life and death of Histogen. But, if those results are favorable, then they’ll move on to pan-Asian phase III trials, and work to get a product out by 2013. So, basically, the 2013 is if EVERYTHING goes according to plan with no unseen circumstances to hinder progress.

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I dont trust this one at all…i dont know why.Just a feeling… i think its a fluke.

7

» I’m confused. They did a very small cohort, and now they’re talking about
» a commercial product? They haven’t even really established efficacy, much
» less safety. And what about their legal troubles? Have those been
» quashed?

I think in order to establish these things, Histogen would have to embark on FDA trails. It’s normally phase one that proves these things. As we all know it’s the gruelling FDA process that normally causes such a delay between establishing effeciency and commercialisation. Even though all their eggs are in one basket, if it works, it’ll be available quick, if it doesn’t we’ll know soon. Can’t really ask for much more than that.

8

» I dont trust this one at all…i dont know why.Just a feeling… i think
» its a fluke.

Maybe its their desperation and hyperbole, but I just get a funny feeling about all this.

9

Well those photos they provided definitely showed what appears to be thickening of hair and more hair overall.

I think the real question about Histogen is what happens with subsequent injections? Do you continue to grow more/thicker hair?

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»
» I think the real question about Histogen is what happens with subsequent
» injections? Do you continue to grow more/thicker hair?

My thoughts exactly.

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» » I’m confused. They did a very small cohort, and now they’re talking
» about
» » a commercial product? They haven’t even really established efficacy,
» much
» » less safety. And what about their legal troubles? Have those been
» » quashed?
»
» I think in order to establish these things, Histogen would have to embark
» on FDA trails. It’s normally phase one that proves these things. As we all
» know it’s the gruelling FDA process that normally causes such a delay
» between establishing effeciency and commercialisation. Even though all
» their eggs are in one basket, if it works, it’ll be available quick, if it
» doesn’t we’ll know soon. Can’t really ask for much more than that.

Exactly. I don’t think Histogen knows the answer to those questions. I’m also suspicious of their attempts to circumnavigate the FDA process - it feels desperate. Personally, I won’t touch anything that isn’t FDA approved - too much risk, especially with something that has the potential to grow tumors. I’d get an HT before I’d ever fly to Asia to have anything done.

12

I’m highly skeptical about this as well. But I think it’s good news anyway - it will put pressure on other companies - such as Aderans - to put a product on the market.

13

She is claiming victory even before the match has started.
Very irresponsable or a plain charlatan.
Lets wait for ARI’s phase II trial. Should be completed by the end of the year.
In the meantime, we will have fun with Dr. Naughton exagerations.

Oh, still waiting for the promised Q&A… … …

edit: I have just seen the video. Now I am even more pessimistic.

» Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit
» “Shelves” As Soon As 2013 - Dated 17th November
»
» Changing the lives of hair loss sufferers forever: Histogen Inc. might be
» doing just that, and sooner than many in the hair loss industry thought.
»
» Watch exclusive American Hair Loss Association Video Q&A of Dr. Gail
» Naughton, Ph.D. as she answers user questions concerning Histogen’s Hair
» Stimulating Complex’s availability, and how it might be used to effectively
» treat hair loss in the very near future.
»

14

I truly don’t understand your resentment towards Histogen. They’ve been upfront about everything thus far: from their lawsuit to how they’re bracing their company against it… from their financial woes to how they’ll raise funds to continue operations… from their trial commitments to how they’ll deal with the corrupt little entity we know as the fda.

They based HSC on a 7 year timeline, and there’s a slight chance we might see this product slightly sooner. They even braced the public that HSC won’t be a “DHT resistenant, one injection will give you a full head of hair overnight” silver bullet. All-in-all, I like histogen because - unlike aderans and follica - they’ve been transparent with their operations and realistic with their goals.

You keep cheering for Aderans, but what have they done for you lately… except, that is, inundate us with a series of Washenik’s interviews where he claimed their product is “less than 5 years away”. Don’t get me wrong, I want Aderans to succeed as much as Histogen, but at this point I’m putting more stock in the later.

» She is claiming victory even before the match has started.
» Very irresponsable or a plain charlatan.
» Lets wait for ARI’s phase II trial. Should be completed by the end of the
» year.
» In the meantime, we will have fun with Dr. Naughton exagerations.
»
» Oh, still waiting for the promised Q&A… … …
»
»
» edit: I have just seen the video. Now I am even more pessimistic.
»
»
» » Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit
» » “Shelves” As Soon As 2013 - Dated 17th November
» »
» » Changing the lives of hair loss sufferers forever: Histogen Inc. might
» be
» » doing just that, and sooner than many in the hair loss industry
» thought.
» »
» » Watch exclusive American Hair Loss Association Video Q&A of Dr. Gail
» » Naughton, Ph.D. as she answers user questions concerning Histogen’s
» Hair
» » Stimulating Complex’s availability, and how it might be used to
» effectively
» » treat hair loss in the very near future.
» »

15

» I truly don’t understand your resentment towards Histogen. They’ve been
» upfront about everything thus far: from their lawsuit to how they’re
» bracing their company against it… from their financial woes to how
» they’ll raise funds to continue operations… from their trial commitments
» to how they’ll deal with the corrupt little entity we know as the fda.
»
» They based HSC on a 7 year timeline, and there’s a slight chance we might
» see this product slightly sooner. They even braced the public that HSC
» won’t be a “DHT resistenant, one injection will give you a full head of
» hair overnight” silver bullet. All-in-all, I like histogen because - unlike
» aderans and follica - they’ve been transparent with their operations and
» realistic with their goals.
»
» You keep cheering for Aderans, but what have they done for you lately…
» except, that is, inundate us with a series of Washenik’s interviews where
» he claimed their product is “less than 5 years away”. Don’t get me wrong, I
» want Aderans to succeed as much as Histogen, but at this point I’m putting
» more stock in the later.
»
»
» » She is claiming victory even before the match has started.
» » Very irresponsable or a plain charlatan.
» » Lets wait for ARI’s phase II trial. Should be completed by the end of
» the
» » year.
» » In the meantime, we will have fun with Dr. Naughton exagerations.
» »
» » Oh, still waiting for the promised Q&A… … …
» »
» »
» » edit: I have just seen the video. Now I am even more pessimistic.
» »
» »
» » » Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit
» » » “Shelves” As Soon As 2013 - Dated 17th November
» » »
» » » Changing the lives of hair loss sufferers forever: Histogen Inc.
» might
» » be
» » » doing just that, and sooner than many in the hair loss industry
» » thought.
» » »
» » » Watch exclusive American Hair Loss Association Video Q&A of Dr. Gail
» » » Naughton, Ph.D. as she answers user questions concerning Histogen’s
» » Hair
» » » Stimulating Complex’s availability, and how it might be used to
» » effectively
» » » treat hair loss in the very near future.
» » »
» » » See Link
» » »
» » »

It’s not histogen’s fault why most of us are overrating their results thus far. They put the pics on a plate, it’s for us to determine what we think of it. The results were so bad in my opinion that some said yes to regrowth, some said no regrowth, some said some thickening only. Are those results really worth looking forward to as much as we are? You can get better results with a simple minoxidil solution. If they on the other hand showed an obvious miraculous-like significant change from nothing to something, then I can understand.

Hopefully their end results will be 500x better. Hopefully. Beyond my control, I personally can’t wait and look forward for it to become commercially available. But I don’t expect better results than ordinary hair loss treatments or even hair transplants for that matter.

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COMPOUNDABLE RESULTS!

Minox does not offer that. It demands continued use but it only gives the initial improvement.

It is an open question of whether this stuff might be compoundable. If it actually is compoundable, then we’re set. In that case it doesn’t matter whether the first pass results are good or just mediocre as long as they do something at all.

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» -----
»
»
» COMPOUNDABLE RESULTS!
»
»
»
» Minox does not offer that. It demands continued use but it only gives the
» initial improvement.
»
»
» It is an open question of whether this stuff might be compoundable. If it
» actually is compoundable, then we’re set. In that case it doesn’t matter
» whether the first pass results are good or just mediocre as long as they do
» something at all.

Why would you scream “COMPOUNDABE RESULTS?” with such confidence as if it were a fact, and then question or not it’s compundable? lol
If they were compoundable, wouldn’t they have shown pictures of patients as a result of multiple sessions/injections over time? Or if they couldn’t, then atleast mention “these results are from one session, in more sessions the results will improve”. If they have said it, then I missed it.

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Remember that the trialists in the preclinical trials were ONLY THINNING. No bald scalps were treated as far as I can remember, and the results were just Minoxidil-Class.
But Naughton, in the 2nd video, is boldly talking about timelines “to get a full head of hair”, no less.
Also, she seems satisfied with the efficacy observed in the preclinical trials and speculates using new sessions to add density, but at this point it is pure fantasy to speculate about this, because she doesn’t know if the results will be additive (most probably they won’t, as it happened with ICX-TRC).
She seems satisfied with the efficacy in the preclinical trials, and she doesn’t talk about improving the efficacy per injection.

She has not said anything about higher doses or improved formulations. Just repeated sessions. This seems to mean that the results we have seen so far can’t be improved rising the dose or improving the formulation, and its necessary to wait 3 months and inject again, and hopefully, see new hairs.
It seems that she aims to reproduce full heads of hair with the current level of efficacy. I think this is impossible.

As you see, everything is unknown, but Dr. Naughton is wet-dreaming about people flying to Asia in 2013 to get “full heads of hair”.

@Rev:
It is true that Histogen has done some good things. They have published pictures, which are top-notch, and they are proceeding quite fast, doing trials in foreign countries to cut-down costs, and speed everything up…
also, they are going to test HSC on 50 trialists in Asia, in Phase I-II, so these are important trials.
But the results are soso, and lately, I have seen a manipulative trend that reminds me of past charlatans. And I don’t like it.

Regarding Washenik, I was very hard against him in the past, when he was constantly advertising HTs for Bosley, promising HM-timelines that never materialized.
I said that “Washwenik was pathetic” after that sad interview when he dedicated most of the time to say how good were Propecia and Minoxidil.
But now things have changed. ARI is doing multicentre Phase II trials in USA, ON VERY BALD PEOPLE, MEN AND WOMEN!!! It seems its 100 trialists.
And Washenik is not giving interviews anymore (afaik). This means no propaganda, but real progress.

» I truly don’t understand your resentment towards Histogen. They’ve been
» upfront about everything thus far: from their lawsuit to how they’re
» bracing their company against it… from their financial woes to how
» they’ll raise funds to continue operations… from their trial commitments
» to how they’ll deal with the corrupt little entity we know as the fda.
»
» They based HSC on a 7 year timeline, and there’s a slight chance we might
» see this product slightly sooner. They even braced the public that HSC
» won’t be a “DHT resistenant, one injection will give you a full head of
» hair overnight” silver bullet. All-in-all, I like histogen because - unlike
» aderans and follica - they’ve been transparent with their operations and
» realistic with their goals.
»
» You keep cheering for Aderans, but what have they done for you lately…
» except, that is, inundate us with a series of Washenik’s interviews where
» he claimed their product is “less than 5 years away”. Don’t get me wrong, I
» want Aderans to succeed as much as Histogen, but at this point I’m putting
» more stock in the later.
»
»
» » She is claiming victory even before the match has started.
» » Very irresponsable or a plain charlatan.
» » Lets wait for ARI’s phase II trial. Should be completed by the end of
» the
» » year.
» » In the meantime, we will have fun with Dr. Naughton exagerations.
» »
» » Oh, still waiting for the promised Q&A… … …
» »
» »
» » edit: I have just seen the video. Now I am even more pessimistic.
» »
» »
» » » Histogen’s HSC - Highly Anticipated Hair loss Treatment Due to Hit
» » » “Shelves” As Soon As 2013 - Dated 17th November
» » »
» » » Changing the lives of hair loss sufferers forever: Histogen Inc.
» might
» » be
» » » doing just that, and sooner than many in the hair loss industry
» » thought.
» » »
» » » Watch exclusive American Hair Loss Association Video Q&A of Dr. Gail
» » » Naughton, Ph.D. as she answers user questions concerning Histogen’s
» » Hair
» » » Stimulating Complex’s availability, and how it might be used to
» » effectively
» » » treat hair loss in the very near future.
» » »

19

mj2003 you missed my point.

I was never arguing that we have valid evidence to get excited about Histogen yet. We don’t.

But I was responding to the comments that the pics show it’s no better than the existing treatments of minox or HTs. It’s not valid to declare Histogen “no better than minox or HTs” before we have an answer on that extremely important detail I was yelling about.

20

cal, don’t hold your breath for the “compounding effect”.

btw, you responded in the wrong place of the thread.

» mj2003 you missed my point.
»
» I was never arguing that we have valid evidence to get excited about
» Histogen yet. We don’t.
»
»
»
» But I was responding to the comments that the pics show it’s no better
» than the existing treatments of minox or HTs. It’s not valid to declare
» Histogen “no better than minox or HTs” before we have an answer on that
» extremely important detail I was yelling about.