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» I picked up some Fincar the other day to use in a topical. I noticed a
» study that showed good results in solution at .005%. That amounts to a
» very small amount of finasteride in the mix. I’m thinking of adding green
» tea extract and also using some emu oil I picked up a while back (as per
» Wasada). What is the best form and source of alcohol to use as a vehicle?
» What are your recommendations for mix ratios etc? Thanks!
Genhair, where Ive bought proscar in the past, has a topical formulation of topical finasteride at .25% and green tea extract at .2%, http://genhair.com/shop/product.php?product_id=10.
Perhaps you could buy one box of theirs and copy their ratios of alcohol and PPG.
The mixes Ive used in the past were adding Pure Grain Alcohol via the liquor store to the water/GTE mix I’d made. I simply addded GTE to what appeared to be the solubility limit to water, and then after added the PGA to it to about a 50/50 or 40/60 mix. Ive not tried finas topically, but I’d imagine what one might do is go ahead and buy a topical finas in a one month’s supply and just copy the ingredient forulation on the back of the box or whatever. I’d venture to guess that PPG and alcohol are used at about a 50/50 ratio with perhaps some denatured water.
Peppermint oil and purified water (its a mixture, so one has to shake it a bit) reduced my beard hair at three months profoundly on one side of my chin vs. the other side. The reason Im inclinded to think something in peppermint oil is quite the anti-androgen (besides the Japanese article claiming it reduced sebum and was an alpha five inhibitor) is that the stuff keeps showing up in so many hairloss products. Tricomin has menthol, Alpecin has menthol, American Crew Thickening shampoo has menthol, Tricomin shampoo has peppermint oil, Revivogen has menthol, Revivogen shampoo has menthol, one of the new Head and Shoulders shampoos has menthol, One formulation of a coal tar shampoo has menthol, Paul Mitchell’s lemon/sage “thickening” shampoo has peppermint in it, American Crew’s “Citrus Mint” has Balm mint, Hair Cycle shampoo has peppermint oil, Alpecin Shampoo has menthol, Revita’s newest shampoo formulation has both menthol and menthyl salyciate or something like that, some of the spiro formulations at genhair have menthol. Why would they all be putting peppermint in these things if its not anti-androgenic?? Peppermint oil is hyper cheap also—a few bucks a year. My advice to anyone considering it is to buy some peppermint oil and purified water, mix it at a 1/40-50 ratio (it burns at a one-to-thirty ratio and is painful) and put it on one side of their beard for three to four months and see for themselves how it can reduce beard hair under androgenic control
Here is the old sciencelinks article on “natural” antiandrogens (I cannot no longer find the link online, but its been posted online in various places):
Activity of herbal extracts on the control of sebum secretion.Accession number;04A0230063
Title;Activity of herbal extracts on the control of sebum secretion.
Author;UCHIUMI YOICHIRO(Maruzen Pharm. Co., Ltd., JPN) YAMAMOTO SUSUMU(Maruzen Pharm. Co., Ltd., JPN) MIZUTANI KENJI(Maruzen Pharm. Co., Ltd., JPN)
Journal Title;Fragr J
Abstract;Potential activity of herbal extracts on sebum secretion was studied. Among the herbal extracts tested, polyol-soluble licorice extract P-U (product name) derived from Glycyrrhiza inflata showed the most potent testosterone 5 .ALPHA.-reductase inhibition, androgen receptor binding inhibition and antimicrobial activities, which are closely related to sebum secretion. In addition to the findings on polyol-soluble licorice extract P-U, clove extract and peppermint extract showed testosterone 5 .ALPHA.-reductase inhibition, arnica extract and rose fruit extract showed androgen receptor binding inhibition, alpinia speciosa root extract and scutellaria root extract showed estrogen receptor agonists, and sophora root extract showed antimicrobial activity. (author abst.)
In case you wondering, you can find some licorice shampoos, as well as some shampoos with clove, arnica, peppermint and spearmint, and rose hips therein also. Why in the hell would a manufacturere bother to put this stuff in shampoos if they thought there was no positive effect is beyond me.
One more thingy on topical finasteride…Dave001, who used to post and was really smart about compounding topicals, used to put finas tablets and spiro tablets in a topical skin cream (Im guessing like Oil of Olay or cetaphil) and use it. He thought quite highly of it. That might be a very effective way to stop further loss also. I would guess he was aiming for about a 1% finas and 5% spiro formulation. Hairmedics, that this website advertises (Hairsite) used to sell a topical finasteride. They are pricey as hell, but again…you might be able to copy their formula if they print it on the package.
Im hoping ICX gets it in gear and gets a working procedure jammin’ so none of us have to concern ourselves with anti-androgens, but until then…back to the salt mines.