Elastin (not dht) Causing hair loss - Interesting Find

Stem cell; cell based hair therapy
1

The following is not typed by me as I am only forwarding the information to you to get feedback.

I do nonetheless find it very interesting. There are some sites to back up the followin data but I don’t want to make this too long.

NOTE : This thread has turned into discussion of many things , especially low dose naltrexone, insulin resistance and other novel theories! It has gotten quite long!

Lets try to keep it on topic regarding LDN, insulin and elastase/elastin so it doesnt get to confusing. The original post below was just an obversation, but I was basically advocating the use of Low dose naltrexone to halt/fix MPB which it seems to have for me along with my Fibromyalgia pains.

Hello,

…I was using avodart with significant success, which was maintained. I stopped avodart due to cost in mid 2004.

My hair declined a little but not horribly.

Now this is very very interesting… I also suffer from fibromyalgia and CFS. I am seeing expert doctor etc etc and I am very up to date on the latest findings and research.

Many have found that elastase inhibitors seem to stop/remiss CFS and fibromyalgia , in short elastase has been found to cleave the antiviral system called RnaseL in these chronic diseases and elastase inhibitors can stop the cleavage and remiss the disease state.

I have been using the following for my illness, and in the process, my hair has grown incredibly! I didnt link anything up until i relalized some correlations!

  1. minoxidil is an elastase inhibitor if you didnt know
  2. elastin is involved in keeping the hair or loosing it
  3. elastase degrades elastin
  4. most of the effective topical remidies that are not DHT inhibitors are elastase inhibitors (ie: emu oil)

So my regimine for my illness, and hair loss / regrowth is this :
low dose naltrexone (www.lowdosenaltrexone.org) - this will take awile to explain but basically it boosts endorphins and the immune system and it frikin works and is cheap. Ask questions or goto the yahoo group. it STOPS multiple sclerosis and cancers etc. There was a worldwide conference in NYC eariler in the month and one of the presentors of the compuding pharmacies noted that several people are using it for “alopecia”. This is when i started researching.

So i use LDN, but i also am using several elastase inhibitors, such as rosemary extract, butchers broom, green tea, and beta lactum antibiotics, all proven elastase inhibiors, systmatically, and lo and behold no more androgentic alopecia!

I propose that the theory of DHT directly causing androgentic alopecia is false. DHT only comes in AFTER elastase degrades the hair connection/tip/follicle. Or alternatively, DHT is increased due to elastase. Stress will bring more elastase, and 5 alpha reductase. Remember that DHT, 5ALPHA is also related to modulation of GABA! So stress really does contribute to hair loss, as does DHT, but elastase is the key element that we are missing.

I suggest elastase inhibitors as a possible treatment for alopecia…

JL

2

Interesting, but… now?

3

Taking this in cojuction to those who want to or are wanting to take duatasteride or finasteride but are effected by the loss of libido. This improves libido, orgasms, and amount of semen by the tons.

Read…

Low dose naltrexone works , by taking a small dose 3.0/4.5mg at night between 9pm-3am when endorphins are produced. It tricks the body into producing more, and by morning you have a lot more. Trust me on this, i know a lot on the subject. MS patients notice it cause they dont have any more progression and it basically cures it. it boosts the immune system somehow in almost all autoimmune and cancer, aids etc.

so you dont use naltrexone or any opiate antagonist, during the day constantly, just the opposite.

libido is EXTREMELY HIGH from LDN. its quite disturbing lol. my orgams are so powerful… i swear… i love naltrexone for that . Its actually so scary im afraid of orgasm cause its so intense!

NF-Kappa-B you have a great point, naltrexone and cap are indeed inhibitors, i think it is def. interesting, cause all these NF Kappa B inhibitors do something that help so many diseases. Interesting thing is Capsacian is also an endorphin RELEASER.

Didnt realize the substance P thing. Neurontin is a substance P inhibitor also.

Interesting about the downregulation of androgen receptors. I wonder if that could be the key.(perhaps Nf-kappa-B controls the protease/antiprotease balance, and one of them is elastase…so if you inhibit NF KB, you inhibit elastase) Naltrexone (low dose) and endorphins are potent NF-kappa B inhibitors. There may be a link between endorphins and NF-kappa-B and protease balance such as elastin/elastase in hair follicles.

4

A couple people here said it increased their hairloss. Of course it may be due to other things. Just noting it.
http://ldn.proboards3.com/index.cgi?board=old&action=display&thread=905

5

These are all females who claim different causes of their hair loss, i.e. childbirth. I can’t speak for them.

But in general, men who suffer from baldness that use hair loss treatments usually experience a shed. Some get minor sheds some get major sheds. Nonetheless shedding is a good sign the user is a good responder.

» A couple people here said it increased their hairloss. Of course it may be
» due to other things. Just noting it.
» http://ldn.proboards3.com/index.cgi?board=old&action=display&thread=905

6

mj2003 Are you tacking it ? It came as 50mg per tab so is imposible to get 4,5mg cutting , may be disolving it ? Do you have a source for 4,5mg tabs ?
Thanks

7

I will be taking it but not now. I am experimenting with dutasteride at the moment in conjuction with minoxidil 5%.

I am looking forward to starting Revia in about 6-8 months.

As per the 50mg tabs, dissolve them in 50ML water so 1 50MG Revia in 50ML water, each ML is equal to 1 MG and use a ML dropper to take.

*Revia = Naltrexone

» mj2003 Are you tacking it ? It came as 50mg per tab so is imposible to get
» 4,5mg cutting , may be disolving it ? Do you have a source for 4,5mg tabs
» ?
» Thanks

8

Here is something related.

http://www.mtrxdsgn.com/haircare.php
http://www.dermalastyl.com/pages/purchase/

9

Will look into the Matrix a little more thoroughly, wonder if I can get my hands on their products.

» Here is something related.
»
» http://www.mtrxdsgn.com/haircare.php
» http://www.dermalastyl.com/pages/purchase/

10

» The following is not typed by me as I am only forwarding the information
» to you to get feedback.
»
» I do nonetheless find it very interesting. There are some sites to back
» up the followin data but I don’t want to make this too long.
»
» NOTE : This thread has turned into discussion of many things , especially
» low dose naltrexone, insulin resistance and other novel theories! It has
» gotten quite long!
»
» Lets try to keep it on topic regarding LDN, insulin and elastase/elastin
» so it doesnt get to confusing. The original post below was just an
» obversation, but I was basically advocating the use of Low dose naltrexone
» to halt/fix MPB which it seems to have for me along with my Fibromyalgia
» pains.
»
»
»
» Hello,
»
» …I was using avodart with significant success, which was maintained. I
» stopped avodart due to cost in mid 2004.
»
» My hair declined a little but not horribly.
»
» Now this is very very interesting… I also suffer from fibromyalgia and
» CFS. I am seeing expert doctor etc etc and I am very up to date on the
» latest findings and research.
»
» Many have found that elastase inhibitors seem to stop/remiss CFS and
» fibromyalgia , in short elastase has been found to cleave the antiviral
» system called RnaseL in these chronic diseases and elastase inhibitors can
» stop the cleavage and remiss the disease state.
»
» I have been using the following for my illness, and in the process, my
» hair has grown incredibly! I didnt link anything up until i relalized some
» correlations!
»
» 1) minoxidil is an elastase inhibitor if you didnt know
» 2) elastin is involved in keeping the hair or loosing it
» 3) elastase degrades elastin
» 4) most of the effective topical remidies that are not DHT inhibitors are
» elastase inhibitors (ie: emu oil)
»
» So my regimine for my illness, and hair loss / regrowth is this :
» low dose naltrexone (www.lowdosenaltrexone.org) - this will take awile to
» explain but basically it boosts endorphins and the immune system and it
» frikin works and is cheap. Ask questions or goto the yahoo group. it STOPS
» multiple sclerosis and cancers etc. There was a worldwide conference in NYC
» eariler in the month and one of the presentors of the compuding pharmacies
» noted that several people are using it for “alopecia”. This is when i
» started researching.
»
» So i use LDN, but i also am using several elastase inhibitors, such as
» rosemary extract, butchers broom, green tea, and beta lactum antibiotics,
» all proven elastase inhibiors, systmatically, and lo and behold no more
» androgentic alopecia!
»
» I propose that the theory of DHT directly causing androgentic alopecia is
» false. DHT only comes in AFTER elastase degrades the hair
» connection/tip/follicle. Or alternatively, DHT is increased due to
» elastase. Stress will bring more elastase, and 5 alpha reductase. Remember
» that DHT, 5ALPHA is also related to modulation of GABA! So stress really
» does contribute to hair loss, as does DHT, but elastase is the key element
» that we are missing.
»
» I suggest elastase inhibitors as a possible treatment for alopecia…
»
» JL

…

11

hey mj2003,as u described that u take rosemary extract,buthers broom,green tea,and ldn…can u please tell me daily supplement value of these herbs…like how much mg rosemary extract to take daily and other herbs.

» The following is not typed by me as I am only forwarding the information
» to you to get feedback.
»
» I do nonetheless find it very interesting. There are some sites to back
» up the followin data but I don’t want to make this too long.
»
» NOTE : This thread has turned into discussion of many things , especially
» low dose naltrexone, insulin resistance and other novel theories! It has
» gotten quite long!
»
» Lets try to keep it on topic regarding LDN, insulin and elastase/elastin
» so it doesnt get to confusing. The original post below was just an
» obversation, but I was basically advocating the use of Low dose naltrexone
» to halt/fix MPB which it seems to have for me along with my Fibromyalgia
» pains.
»
»
»
» Hello,
»
» …I was using avodart with significant success, which was maintained. I
» stopped avodart due to cost in mid 2004.
»
» My hair declined a little but not horribly.
»
» Now this is very very interesting… I also suffer from fibromyalgia and
» CFS. I am seeing expert doctor etc etc and I am very up to date on the
» latest findings and research.
»
» Many have found that elastase inhibitors seem to stop/remiss CFS and
» fibromyalgia , in short elastase has been found to cleave the antiviral
» system called RnaseL in these chronic diseases and elastase inhibitors can
» stop the cleavage and remiss the disease state.
»
» I have been using the following for my illness, and in the process, my
» hair has grown incredibly! I didnt link anything up until i relalized some
» correlations!
»
» 1) minoxidil is an elastase inhibitor if you didnt know
» 2) elastin is involved in keeping the hair or loosing it
» 3) elastase degrades elastin
» 4) most of the effective topical remidies that are not DHT inhibitors are
» elastase inhibitors (ie: emu oil)
»
» So my regimine for my illness, and hair loss / regrowth is this :
» low dose naltrexone (www.lowdosenaltrexone.org) - this will take awile to
» explain but basically it boosts endorphins and the immune system and it
» frikin works and is cheap. Ask questions or goto the yahoo group. it STOPS
» multiple sclerosis and cancers etc. There was a worldwide conference in NYC
» eariler in the month and one of the presentors of the compuding pharmacies
» noted that several people are using it for “alopecia”. This is when i
» started researching.
»
» So i use LDN, but i also am using several elastase inhibitors, such as
» rosemary extract, butchers broom, green tea, and beta lactum antibiotics,
» all proven elastase inhibiors, systmatically, and lo and behold no more
» androgentic alopecia!
»
» I propose that the theory of DHT directly causing androgentic alopecia is
» false. DHT only comes in AFTER elastase degrades the hair
» connection/tip/follicle. Or alternatively, DHT is increased due to
» elastase. Stress will bring more elastase, and 5 alpha reductase. Remember
» that DHT, 5ALPHA is also related to modulation of GABA! So stress really
» does contribute to hair loss, as does DHT, but elastase is the key element
» that we are missing.
»
» I suggest elastase inhibitors as a possible treatment for alopecia…
»
» JL