I have been on Dutasteride since it first came out in December 2002 (from memory). I started at 0.5mg daily then tapered down to just 0.5mg on weekdays after about 3 years and I now take 0.5mg on Mon, Wed and Fri. No great results to speak of: has simply maintained what I had pretty well, no more, no less. I also use Minoxidil 5% once daily and have been for years.
My concern about Dutasteride is the long-term safety and I am now considering moving back to Finasteride (1.25mg per day) which is not only cheaper but a safer drug long-term in terms of what data we know of it anyway.
I am not saying Dutasteride isn’t safe, in fact the trials on rats showed very little effects. But I am concerned that we simply don’t know what the results will be in 20 years of long-term use and we are the “guinea pigs” right now.
Has anyone had any side-effects long-term of Dutasteride? I can’t say I have other than a flicky eyelid (which I have had for a while off and on) - but you never know.